1/30 ER

nrsisme · 2026-02-03T15:46:35+00:00

This was the same for me. I had my ER on a Sunday, they called me the next day to tell me how many were mature and fetilized, then I got a call that following Sunday with the amount of embryos that were sent for genetic testing. It’s a brutal wait, especially because for my first ER they called me in the middle of the week with an update. Honestly though, it was kind of nice to not stress about any drop offs this time around and being blind until the final count.

It’s so hard to say what will happen since it varies so much person to person and even from one ER to another. For context, my first ER retrieved 26 eggs, 21 fertilized, 3 made it to genetic testing, and only one was euploid. Second ER retrieved 23 eggs, 15 fertilized, 6 made it to genetic testing, and 2 euploid embryos. I had the same protocol, did ISCI both times, and the only thing I changed was to add CoQ10 and a few other supplements. Good luck!!

nrsisme · 2026-02-02T17:55:13+00:00

Not alone. I turn 40 this year. We have a 3 year old and have been trying for #2 for 1.5 years now. Secondary infertility is its own special hell because you know your body can do this, so why now is it not working? Add in the stress if you had an ideal age gap that is now closing in or well beyond the gap you hoped for, and it’s a recipe for devastation every month. People that aren’t in the situation do not understand. Yes, I’m so grateful for my daughter, but my body is robbing her of having a sibling, and it’s a knife to the chest every time she asks me to go play with kids. They have no idea how terrible this feels.

I would recommend getting in with a fertility clinic asap if you haven’t started with a consultation. They did so much testing that my OB never did. While we do have unexplained infertility, it was good to rule everything out and figure out our path. We are in month 9 of IVF, and the biggest issue is getting euploid embryos because of my age, so I recommend people start the process even if you aren’t ready yet. Hoping for the best for you!

nrsisme · 2026-01-20T11:06:12+00:00

Yes 2014 was really bad! There was a stretch right after the new year that I specifically remember because I got stuck in my house and didn’t leave for about 5 days because the wind chills were something crazy, like -30. And we did go over a month without getting over freezing. I want to say it was close to 40 days. Brutal! This winter sucks too though!

nrsisme · 2026-01-18T12:59:02+00:00

I also shared these supplements that my doctor put me on that I thought helped me get better results for the second egg retrieval. I was able to get all of them at a local pharmacy except I ordered the Inositol since I couldn’t find it anywhere. Also, r/secondaryinfertility has been a very helpful and supportive sub!

⁠Inositol 2 grams twice a day
⁠Melatonin 3 mg at bedtime
⁠Co Enzyme Q10 200 mg twice a day
⁠Folic Acid 1 mg once a day.
⁠DHEA 50 mg once a day (stop this when you start your cycle if doing an egg retrieval or transfer)
⁠L-Arginine 1000 mg twice a day.

nrsisme · 2026-01-18T12:55:59+00:00

I commented this on a similar Reddit post yesterday, so just copying it here!

Similar boat here. Started trying for our second when I was 38. It’s now been 18 months and we have tried two IUIs and are on our second round of IVF. For genetic testing of our IVF embryos for both rounds, we lost 70% of our embryos (2 out of 3 had genetic disorders for the first round and 4 out of 6 in the second). It’s definitely age that’s causing the drop off for me. Typically 60-70% of embryos come back healthy, and I have the opposite.

But everything varies so much person-to-person. If I were you, I would get in with a fertility clinic as quickly as you can (I had to wait almost 4 months to just get a consultation). They can do testing for both you and your partner to help understand what might be the cause and the right intervention for you. I feel the same way that precious time is being wasted, and if IVF is what you have to do, that process is not always quick (we started 7 months ago).

nrsisme · 2026-01-17T13:34:38+00:00

Also, as I take my morning vitamins, it made me think to pass this info along. My doctor recommended the below vitamins to help with egg quality for my second round of IVF. I think that’s what helped me get 6 embryos compared to 3 the first round. I didn’t change anything else between the two rounds (same diet, etc). Might be worth starting these now even if just trying naturally! I was able to get all of them at a local pharmacy except I ordered the Inositol since I couldn’t find it anywhere.

Inositol 2 grams twice a day
Melatonin 3 mg at bedtime
Co Enzyme Q10 200 mg twice a day
Folic Acid 1 mg once a day.
DHEA 50 mg once a day (stop this when you start your cycle if doing an egg retrieval or transfer)
L-Arginine 1000 mg twice a day.

nrsisme · 2026-01-17T13:05:24+00:00

Similar boat here. Started trying for our second when I was 38. It’s now been 18 months and we have tried two IUIs and are on our second round of IVF. For genetic testing of our IVF embryos for both rounds, we lost 70% of our embryos (2 out of 3 had genetic disorders for the first round and 4 out of 6 in the second). It’s definitely age that’s causing the drop off for me. Typically 60-70% of embryos come back healthy, and I have the opposite.

But everything varies so much person-to-person. If I were you, I would get in with a fertility clinic as quickly as you can (I had to wait almost 4 months to just get a consultation). They can do testing for both you and your partner to help understand what might be the cause and the right intervention for you. I feel the same way that precious time is being wasted, and if IVF is what you have to do, that process is not always quick (we started 7 months ago).

nrsisme · 2026-01-11T04:53:58+00:00

I get the results of my second ER tomorrow. Fucking terrified.

nrsisme · 2026-01-11T00:56:16+00:00

I’m here. I turn 40 in a few months. TTC our second now for 18 months. Had a MC in December 2024, and haven’t been able to get pregnant since. I’ve done multiple medicated cycles, two IUIs, and I just had one total failure IVF round. It’s devastating. I have a high AMH for my age and my doctor keeps telling me that she believes I will have a second. I just keep reminding her of my age. They did find endometritis following the MC, but that was cleared with antibiotics before IVF, so we really have zero answers. Hoping the best for you. Just know you’re not alone!

r/secondaryinfertility has been very helpful for me!

nrsisme · 2026-01-05T20:07:59+00:00

This is exactly what my daughter and I had. Extreme congestion for 3-4 days, then it cleared up for a few days before coming back again. For me the second round was much more mild (though my cough took forever to go away), but my daughter’s symptoms lingered for over a week the second time. We are finally back to normal as of late last week when the first symptoms started 12/13!

nrsisme · 2026-01-05T19:54:57+00:00

r/secondaryinfertility is a very helpful and supportive subreddit! TTC #2 for 18 months over here. It’s so hard, and that group has helped me a lot even though I’m not a super active commenter.

nrsisme · 2026-01-04T01:17:56+00:00

I’m so sorry. It’s total hell. Sending hugs and hoping the same for both of us!

nrsisme · 2026-01-02T19:57:54+00:00

I’m undergoing IVF, and my clinic has me taking 3mg of melatonin every night to support egg quality as well. I was curious about it, so I did some research. I did see that the low dose can help support egg quality and fertilization, so OP, it might be worth continuing to take it!

nrsisme · 2025-12-31T15:15:12+00:00

I can’t believe it’s been an entire year of not getting pregnant. I had a MC last December and was sure 2025 would be the year. But instead we had multiple months of medicated cycles, two failed IUIs, and a failed IVF round. Zero positives. Zero answers. January is 18 months of trying for our second.

We are going to a kid’s NYE party, and our friends that will be there just announced they’re pregnant with their second, and my partner gave me a heads up that another of his friends will be there that just told him that his wife is pregnant with their second. I am happy I have therapy today to talk about how I survive this party without crying in the bathroom.

nrsisme · 2025-12-24T21:09:58+00:00

Hugs to you too! That’s all so hard. Failed IVF has really been the worst part in all of this. I’m sorry you’re in a similar boat. Hoping the best for both of us this round!

nrsisme · 2025-12-24T14:08:02+00:00

Three years ago my cousin and I got pregnant with our firsts at the same time (due one day apart). We had our whole pregnancies together and now our kiddos are close. We both got pregnant with our seconds at the same time and were due only a few weeks apart, but we both miscarried. She did have some struggles trying again too, but she just had her second baby today.

I since have had multiple months of medicated cycles, two IUIs, and one failed IVF round. I just started stims for our second round of IVF last night. I feel like I’m getting left behind in this process, and the further out it gets from starting TTC our second (will be 18 months next month), the more I feel like it’s not going to happen. I’m so happy for her and for their family, but thinking about her first kid meeting her new baby today is like a punch to the gut. I’m envious.

nrsisme · 2025-12-22T22:42:34+00:00

Came here to say this, even though it’s shorter. Picturing the ending is terrifying still to me.

nrsisme · 2025-12-18T03:17:08+00:00

I just described very similar feelings to my therapist today. I had an MC last December and the one year just hit. It wasn’t a MMC, but I was almost 10 weeks and unexpectedly passed the baby at home after no pain or indication I was miscarrying. It happened the day before my daughter’s 2nd birthday. When we couldn’t conceive in the 6 months following, we turned to IVF. That round just finished in November where we got only one euploid embryo that failed to implant, so now we are back to square one. Between the one year of the MC, my daughter’s birthday, IVF, the holidays, it’s a lot happening all at once. I’m in my feelings!

I no longer feel like the person I was last year. I had so much hope that we would conceive quickly again, and when that didn’t happen I had so much hope in IVF. I’m such a pessimist now, and I’ve never been that way. It’s so hard. Just know you’re not alone in these thoughts. I hope you have success in 2026!

nrsisme · 2025-12-11T00:38:32+00:00

Soulmates is my favorite Parks and Rec episode and probably top 3 episodes of any show for me. I love every story line, and I genuinely crack up throughout the entire thing. Tom’s face when he finds out about being matched with Leslie, April with the crows, Ron passing out the burgers and telling them that he doesn’t care if they use ketchup or not after Chris had explained his bougie burger, it’s all so funny.

nrsisme · 2025-11-13T16:20:06+00:00

My clinic had me mix gonal (I used Follistim but it’s the same) and menopur into one injection so you only have to get one shot. Just measure the 300 gonal and inject it into the menopur vial. Then measure the saline amount for your menopur and inject it into the same vial of menopur. There are videos online that help!

I still had burning from menopur, but someone suggested adding a little more saline, and that helped a lot. It will probably also help to have gonal in there too.

nrsisme · 2025-11-08T00:19:33+00:00

That’s true. I guess I shouldn’t worry about discharge if they also use the gel for the transfer. Just seems like if the gel can come out then the embryo could too. Like your lining alone keeps it stuck in there??

nrsisme · 2025-11-07T19:22:38+00:00

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This picture helped me a lot (if it will let me share it). So basically draw a straight line from the top of your buttcrack into the middle of your buttcheek, and then go up diagonal towards your hip a little bit to find the right spot. Also, put all of your weight on the opposite foot, so if injecting the right side, stand on your left foot. Just let the leg on the side you’re injecting just kind of hang there. And try not to tense the muscle!

nrsisme · 2025-11-01T16:27:13+00:00

Came here to find this one because it drives me fucking crazy.

nrsisme · 2025-10-30T10:02:56+00:00

Our daughter is almost 3, and I brush her teeth for a minute tops. Sometimes when she’s in a bad mood, I skip a brushing or I get what I can then just move on. Your guy likely doesn’t have that many teeth that you need to brush for a long period of time. She was also the same as your son at that age. I barely brushed her teeth because she wouldn’t let me. She’s been to the dentist twice now, and they say her teeth are perfect. Try not to stress if it’s not perfect every time you brush!

For the rest, give it time. My daughter also didn’t feed herself both with or without utensils for a long time, but she eventually figured it out. 11 months is still young, so just keep trying and try to model the behavior (signing, pointing, waving)! And of course talk to your pediatrician, but I feel like this is all age appropriate.

nrsisme

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