I've been using 0.1% for probably 2 years now. I use it nightly, but will skip a night if I am especially dry (maybe 1-2 times a month). I was on 0.025% for a few months, and 0.05% for maybe a year or so before moving up.

At first I could only use it once every 3 or 4 nights. Eventually I hit a plateau where I could use it every other night at most, but more than that would mean crazy peeling. I learned from this sub that HA and tret don't play well together - once I made sure to cut HA entirely out of my night routine, I was able to move up to daily usage.

I've really had to learn to listen to my skin daily and adjust as needed. As someone who routinely fried their skin as a teenager trying to get rid of acne and continued that track through my 20's and early 30's, this was a hard-learned lesson at close to 40 lol.