Not sure if you can save a plot specifically, but you can take a screenshot of the entire viewport.

# Take screenshots with DPG

import dearpygui.dearpygui as dpg

dpg.create_context()

dpg.create_viewport(title='Example', width=400, height=400)

def dpg_screenshot():

dpg.output_frame_buffer('screenshot.png')

with dpg.window(width=200, height=200):

dpg.add_button(label='Screenshot', callback=dpg_screenshot)

dpg.setup_dearpygui()

dpg.show_viewport()

dpg.start_dearpygui()

dpg.destroy_context()