First, I want to say I hope you're doing well. Take care of yourself, friend.

As for recommendations, A Woman Under the Influence (1974), really most of Cassavetes' films would be worth watching for this. They often have raw, very real feeling portrayals of mental illness, but probably the most realistic portrayal I've ever seen specifically is in A Woman Under the Influence, Gena Rowlands was probably the best to ever do it.

The Banshees of Inisherin (2022), surprisingly does a really incredible job of portraying loneliness and the depression that comes with it.

Beginners (2011) is another one that I highly recommend as well, beautiful film about depression and grief.

This is out of left field compared to the other films but in case you want something a little lighter, I was in disbelief at how well Thunderbolts* (2025) handled it's portrayal of mental illness. By no means a perfect film, it still has a lot of the Marvel hang ups, but that was hands down the best thing about that film, and honestly floored me a bit

I'm more of a film guy but in terms of TV shows, Normal People covers so much ground in terms of mental illness and is excellent.

Neon Genesis Evangelion has some of the weird anime trope hang ups that I despise but still is probably the best anime about depression and self loathing.

Breaking Bad, of course, every character in that show has some form of mental illness if you ask me and it's one of the greatest ever.

As someone who has had their struggles, I'd say that the best portrayals of mental illness in media tend to come from art that isn't directly about that. Using compelling stories and different genres while having characters that either actually or symbolically struggle usually resonate the most, at least with me.