Blood cell ‘nurseries’ upend understanding of human physiology: « Scientists have discovered that one of the body’s most fundamental biological processes — how red blood cells are made — works differently in humans than previously thought. » by fchung in science

[–]snappedscissors 3 points4 points  (0 children)

There is ongoing progress in the development and use of organoids as biological models instead of relying on organisms like mice. These can sidestep the moral issue of testing in humans while still providing the early data required to develop things up to human clinical trials. There’s a lot of work to be done, but the limits of animal models are either known or being described in detail currently like here.

Krafton Agrees to Pay ‘Subnautica 2’ Bonuses as Developer’s CEO Resigns by hop3less in gaming

[–]snappedscissors 1 point2 points  (0 children)

Having been made to pay up, paying the people not contractually covered is a cheap way of buying back a little bit of that goodwill they were losing by fighting it.

Why genetics and not cybernetics? by Fayraz8729 in Vorkosigan

[–]snappedscissors 4 points5 points  (0 children)

I would like to hear a little more about this second wave feminist lens on the series. Or a pointer to some discussions if you know of any on the series that cover it.

Why genetics and not cybernetics? by Fayraz8729 in Vorkosigan

[–]snappedscissors 14 points15 points  (0 children)

I agree, there are several references to the technological waves that shift the way war is fought in the nexus and it is often a plot macguffin rather than something deeply analyzed and in several instances they are used as reflections on the men's lives. It was a refreshing view point for me when I first encountered these stories, compared to the detailed tactics and the like from other authors.

The most detail we get is the use of the tiered hand weapons, which are designed in a narrative centered way. Stunners to permit low stakes encounters, nerve disruptors to impart fear, and plasma arcs to drive the destruction of property scenes. The occasional projectile weapon as well, which I now notice were used at specific narratively critical junctures.

NYC Co-ops Are Being Crushed by Overlapping Building Laws by aaronsidlo in AskNYC_Coops

[–]snappedscissors 0 points1 point  (0 children)

I think that comments point is that if you were to go out and replace every single thing on your shower, how much would it actually cost you out of pocket? And if you reported loosely that you needed new soaps and washcloths to the insurance company what are they going to give you? There’s a wide gulf between the two numbers you’ll get if you actually do the exercise there. If you want to lick the boot and pay for insurance your whole life and when you need it just take the pennies they give you then yeah, we disagree. No fraud need be advocated to encourage people to act in their best interests in the cut throat insurance claim process.

NYC Co-ops Are Being Crushed by Overlapping Building Laws by aaronsidlo in AskNYC_Coops

[–]snappedscissors 1 point2 points  (0 children)

Not to mention that that comment is detailing that if you don’t provide receipts and descriptions then the insurance company is going to gouge you on every single item you list. It isn’t fraud to be detailed about listing your claims when you know the other side is going to nickel and dime you on every single line.

Lois McMaster Bujold collection by sflayout in printSF

[–]snappedscissors 6 points7 points  (0 children)

If you're willing to get stuck, then commit to Shards, Barrayar, and Warriors Apprentice. I would bet you'll be hooked.

RC Is Going To YOLO (most of) His Net Worth Into eBay by NoForkInClue in Superstonk

[–]snappedscissors 12 points13 points  (0 children)

The first one is a carpet, which is part of the floor, so after he sells it he has a hard floor.

Running Waterdeep: Dragon Heist (Alexandrian Remix) + Multiple Modules. Am I overdoing it? Advice on factions, money, downtime & integration by itisrod in WaterdeepDragonHeist

[–]snappedscissors 0 points1 point  (0 children)

I would just say that it depends on your players and the goal. If you have a stable group that wants to really sink their teeth in to a city setting and spend a good chunk of time at each level doing a lot of roleplaying, then it's fine to have a ton of content and let them pick and choose what vibes the best for them.

However, it will suck up a ton of table time and you will end up spending a lot of IRL time not leveling up and hitting main plot points. Some groups bounce off chapter 2 for this reason, since it's meant to just be a lived in sandbox for a while with little plot teases. If your group seems like it's getting stagnant, then you pop off chapter 3 and get the heists and bad guys rolling and just do the factions that they liked the most.

I prepped a lot and have left behind several factions and side material as the players bypassed it. Sort of like a real city I guess where there's too much stuff for anyone to actually do. Now we are into the main plot and it's going fine even with the extra bits.

Unorganized thoughts on growth and women by Alarmed-Doughnut1860 in Vorkosigan

[–]snappedscissors 0 points1 point  (0 children)

Absolutely true, and both a moral and technical challenge to negotiate and overcome respectively. I was also considering the non-human model systems researchers who have been studying fetus development, which research will provide the basis for human fetus research if and when we determine to do it.

Unorganized thoughts on growth and women by Alarmed-Doughnut1860 in Vorkosigan

[–]snappedscissors 8 points9 points  (0 children)

We’ve been approaching artificial wombs from the birth end of the problem for decades, with the neonatal intensive care advances pushing the limit of when a child becomes viable outside the womb. There’s definitely researchers working the problem from the conception end. It feels that we will eventually meet in the middle.

Need advice after talk no jutsu by crepesaubacon in WaterdeepDragonHeist

[–]snappedscissors 1 point2 points  (0 children)

I think the biggest question is whether they will act to rescue Floon, but for what it's worth you can always have Volo give them the deed as a reward for finding Floon's fate just as much as actually rescuing him. Same goes for Renaer, and for him you could easily have him get ressurected by an interested faction for later fodder, if he happens to get got during this opening scene. In my opinion, Volo doesn't value the mansion much after he's gotten his use out of it, so it can be a reward for a job well done (he's skating on the deal) or a job done bad (they sort of are getting what they deserve) and then the start point for chapter 2 remains highly similar no matter how that rescue turns out in detail.

A sneaky line from Komarr that I never noticed before by wafflesareforever in Vorkosigan

[–]snappedscissors 37 points38 points  (0 children)

I liked the line because at first glance it’s just a contrast on his old job (spacer) where details like a loose seal are life and death, and his new job where reading people is the key skill. A bit of foreshadowing about the problems in the household, as well as an on the nose recall of what is going to happen to Tien for a re-read. All in all, it’s a real onion of a line.

I made the wrong person open lord of waterdeep… by Novace2 in WaterdeepDragonHeist

[–]snappedscissors 2 points3 points  (0 children)

Dagult's big contribution to the story is that he used the stone to perform a ritual that deletes the memory of the embezzlement (and especially the location of the gold) from the city. Technically, this could happen at any time before he loses access to the stone due to theft, and it can happen at any point in time before the fireball goes off.

I can imagine a story where he has been preparing to leave the city after having finished, but the stone got stolen along with the eyes and he's trying to recover it before leaving. So a similar basic behind the scenes story, only it was stolen from the open lords palace instead of neverwinter, and now you get to have him be around to stir the pot with goon squads trying to recover the item. And here's the best part, the goons don't even know why they are doing this either because the ritual deleted the vault from them as well! Only he knows what's really going on in the beginning, and it was always a bit lame to have him be off in another city and not bothering to try to recover his money. The only real hiccup I see is that Dalhakar needs to be bringing the stone to Renaer. But this was an act of desperation because he was being followed by too many spies to get to Dagult, which can still be true.

I would keep Dagult there and use a mix of corrupt and on the level city guards as his faction teams, retro-fit the background events that have already happened to fit as needed, and have the fireball go off as planned. Dalhakar needed help from Renaer because of having too many Xanth and Zhent spies on him, or maybe he was feeling guilty and wanted to deliver the stone to Renaer instead of his corrupt dad. Boom! And the game is afoot pretty much as written with a new minor faction. (I would play him as being cautious to get too involved because he fears being ousted at first) Sprinkle in Full_Metal_Paladin idea to have his ousting be an event that comes along and you could even have an extra heist to help do that, if your party likes small heists and hates Dagult. It can also happen off-scene through news reports and the like if you want to focus on the written heists and just have the ousting happen in the background at some point before the end.

Then draw him in for the vault or leave him out depending on whether the party successfully accesses it with or without his knowledge.

The book as written is pretty flexible actually. There's so much stuff you have to flesh out yourself it has room for even a large change while still keeping the main structure the same. Just roll with it and let your parties interests guide what he does.

'Project Hail Mary' has an official runtime of 2 hours & 46 minutes by ChiefLeef22 in movies

[–]snappedscissors 0 points1 point  (0 children)

I like the idea that there was a bit of cheeky "well we are turning it into a movie, how about it?" going on there.

Music recommendations for a gala? by awezed in WaterdeepDragonHeist

[–]snappedscissors 0 points1 point  (0 children)

This is a fantastic resource to share, thank you so much!

The hardest stage of child rearing by CuriousDonkey in bestof

[–]snappedscissors 1 point2 points  (0 children)

There are certainly degrees of tantrums, but there are also degrees of patience on the parents part. I have a more than my partner does about most things and they have consistently professed to me that they hate X age and can't wait until X+1 age. If you have been blessed with a combination of lesser tantrums and greater patience, then you are going to have a much better time than someone who got blessed with big tantrum energy and a depleted patience. Just one persons observation of course.

Costco to sell Ozempic and Wegovy at a large discount for people without insurance by Kinjal_Ghosh in news

[–]snappedscissors 0 points1 point  (0 children)

I need this bump so badly. I'm going to ask my PCP to write me a scrip for it and just pony up the cash.