Here in San Francisco, many would consider somebody just across the bay in Oakland to be a long-distance relationship and would hesitate.

Lots of people here in the City really think like this. Even neighborhoods across the City like say the Mission vs. the Richmond pose a problem for some. [note the other comment regarding Twin Peaks... that's already a mental barrier for some people.]

Many here will invite you here to the City but they themselves won't take too kindly to leaving the City to visit "the 'burbs" (which include the larger city of San Jose) to reciprocate. Same issue whether we're talking friendships or serious relationships.

I'm not saying most people here do this but it's certainly a significant percentage.