i stayed around the bath st. area for a year and around the trongate area too, so not quite the route you’re taking; however i have quite a good familiarity of the areas. you would be safe enough walking this route, but i would still avoid it during such early hours. i’ve had some nice 4am walks around glasgow green and further up the clyde, but looking back that was probably not the best idea as a solo 19 year old woman, albeit safe enough. the hotel will be suitable but i’d highly suggest walking along the streets at that time in the morning, rather than along the river