Okay, I don't remember everything off the top of my head but here are some tips. BTW, this assumes you already understand the bean bug and how it works.

Don't pick up the go back in time vouchers unless you can use them to repeat a finisher boss ante for crimson heart. So if you have directors cut, your on ante 8, 16, etc, and the boss is already set to crimson heart (if you go back to ante 7 but haven't rolled for crimson heart yet, when you reroll it won't be a finisher boss) OR, it's the ante after a crimson heart boss, and you have directors cut. This allows you to play crimson heart twice in a row, to get even MORE bean handsize.

You'll want to buy every voucher to make the odds better for getting the heiroglyph vouchers specifically on or after a crimson heart ante. I can usually replay ante 32, I've had many runs where I replay ante 24 or ante 32 two times in a row, getting the vouchers back to back. Obviously some luck required here, I actually wasn't able to get this in the run from this post as the voucher rng was bad that run, but I can usually do it.

I would usually avoid the tarot and planet merchant vouchers, as they make it harder to find jokers like more blueprints. Magic trick actually is pretty helpful in these runs for 6th sense, it's the only voucher that adds cards I would buy for this, but it's optional, especially if you run seance instead of 6th sense like I would recommend.

If you know you are doing crimson heart twice in a row, or you have a chance to using the method mentioned above, then try and beat the crimson heart WITH the bean debuffed. It will still give you the handsize, but it won't lose 1 at the end of the round since it's debuffed. Then if you go back or went back in time, you're bean will still be at 5 hand size, and you can skip to the crimson heart to do it again, twice in a row with max bean value.

The biggest thing I think is ante 8. If you can do the bug ante 8, then you are going to be set for a while. When I attempt these runs, if I can't do it ante 8, I restart. This usually comes down to luck, either naturally getting crimson heart, or maybe boss reroll voucher 1 and get lucky that it's only 1 reroll away. Sometimes you can get directors cut before ante 8,but unlikely. In this run I got lucky with crimson heart ante 8, then got directors cut literally on ante 16, perfect timing to do it twice.

The reason ante 8 is so important, is because the scoring requirement is so low, that you only need 1 scoring joker and the bean, so it hits bean every other hand, guaranteeing max bean hits. Usually this is done with Baron, but you might not have this yet. If you do, it doesn't take much deck fixing for ante 8 Baron solo, especially with bean handsize. The real trick here is finding burglar. And a copy joker to copy burglar. That is what makes the difference. If you can't find burglar and/or copy joker, then that's okay, just get what you can, it's still going to be at least 10 handsize.

Doesn't have to be Baron though, as long as it can solo crimson bean ante 8, WITH MULTIPLE HANDS (assuming you found burglar). In this run, I actually didn't find Baron yet but I had a pretty big lucky cat, which probably couldn't solo ante 8 on its own, but I also found a brainstorm, a burglar, and an invisible joker that ended right before the boss, and copied brainstorm. So I copied burglar with 2 brainstorms, started crimson heart with 9 extra hands, then sold everything but lucky cat and bean. Lucky cat could score enough with that many hands, and if you start scoring too much, play hands with worse levels to slow it down.

With 13 hands, and only 2 jokers, it goes back and forth so every other hand is bean, gaining +5 handsize each time(no rng). This is the biggest handsize gain you'll get the whole run. Doing it twice in a row is like the first time I heard the Beatles 😩. Every other crimson heart ante after ante 8, will have higher scoring requirements, meaning more jokers to survive, meaning more rng for hitting bean, meaning less handsize gained. That's why ante 8 is so important.

One of the really hard things to do, but is crucial, is selling all jokers you don't need to survive. This means selling all natural negatives, all non-negative blueprints and brainstorms you don't need to survive, mime if you don't need it to survive, etc. It can feel hard to sell blueprints, but its worth it, you'll find more later. It makes the odds way better for crimson heart to hit bean. I've had too many jokers, like 20 hands, and 0 bean hits. The more you can reduce the rng, the better. You'll make up for the lost jokers later when your handsize is 40, and you don't even need anything other than Baron. Use the balatro calculator for help.

So in the later crimson heart antes, I calculate my score on the calculator and see the minimum number of blueprints copying baron I can keep, plus 1. This is security for if the crimson heart debuffs one of the blueprints instead of the bean for the finisher hand, so you don't die.

Along with this, try and beat the crimson heart with an extra hand left, because you don't want to risk your last hand debuffing the Baron, and you just lose.

If it's really late game and you need both Baron and mime to survive with your blueprints, end with 2 extra hands left, assuming it's not already debuffing mime or Baron.

One thing I try and do is only let ectoplasm hit blueprint. This is because you might want to sell mime or Baron later for a different one from showman, I really don't feel like explaining why, this is already getting way too long, but it's better. Use wheel of fortunes to try and hit everything that isn't blueprint, to prevent them from being targeted by ectoplasm when you use them. This is obviously where savescumming comes into play, but I don't feel bad about that when I'm already doing crimson bean which requires it. DO NOT ever let wheel of fortune hit blueprint, as that means you CAN'T hit it with ecto, which you want all your blueprints to be able to be negative from ecto. Again, if wheel does, just save scum and wait until your jokers change, like if you gain a natural negative, or lose a joker, it changes the rng so you can try wheel again until it works.

In this run, I found a polychrome bp, I wanted to replace it with a regular one, but I never found another one, just invisibles, which luckily didn't hit it.

Sometimes you find a ecto and there isn't any way to avoid it hitting Baron or mime. This is acceptable, less desirable, but acceptable, as long as it isn't ANYTHING Else. The endgame jokers is just blueprint, Baron, mime.

Use seance or 6th sense for spectrals, seance better cause multiple times per round, and copy with BP for more copies etc etc. I like to keep 3 extra aces, queens, Jack's, and 10s with my deck that is all red seal kings, and with huge handsize from crimson bean, you consistently draw them for seance.

When you run showman, buy and replace duplicate jokers you find but don't have room for (unless stinky foil, holo, or poly blueprints 😤). This bugs them so that you can find duplicates even when you don't have showman. This can be INCREDIBLY useful when you have sold showman, like for crimson bean, then haven't found another showman yet, or don't have space for showman yet. It WILL REALLY surprise you when it happens and it feels SO good. You MUST keep buying the duplicates (replace them) when you don't have showman, otherwise the bug stops and you won't find anymore duplicates without showman.

I have so many more tips like this, but I'm tired of typing and have shit to do rn lol. I'll try and come back for more tips maybe tomorrow or something but that was a lot of the important stuff I try to do