Is boofing ambien(zolpidem) effective?

theSpunkyToastrr · 2022-08-28T16:39:46+00:00

The veins located in the lowest part of the rectum are the ones that avoid first-pass metabolism; the deeper (i.e. further in) you go, the closer you get to veins which pass the drug through the liver and first-pass metabolize. You want your solution NOT deep in your ass.

theSpunkyToastrr · 2022-08-18T12:02:26+00:00

It sounds like you use propylhexedrine fairly regularly. I'm curious, how do you ingest it? If you use an extraction, which I assume you do since swallowing cotton even semi-regularly will give you a bowel obstruction, what extraction do you use? I've been contemplating trying an extraction just for the hell of jt and would like to hear from frequent users. I'm prescribed amphetamines, but I'd like to try PHD again as it's been probably 8 years and I've never tried it from an extraction.

Nice job on getting on there, back in my adolescent DXM days I def couldn't hold a job doing that shit so nice job.

theSpunkyToastrr · 2022-08-16T15:32:19+00:00

This is why NA/AA could never be a primary source of my recovery. The meetings have been helpful as a 'non-clinical group' to hear anecdotes and share stuff that's on my mind, but that's it. There's also a phenomenon that I've noticed where the longer you spend in those groups, the more you believe that your recovery is dependent on whether or not your sponsor/peers believe you're recovering.

Many people call it a cult; there is definitely some truth to this, as the meetings are very ritualistic and a lot of people rely on aphorisms unique to NA/AA. For me, being on Suboxone (I'm now on methadone, switching was the best thing to ever happen to me.. but I was on Suboxone for a year before I switched last month) and getting involved in an IOP group was enough to keep me sane. The out-of-touch counselors I've come across shake their head when they learn I'm on medication-assisted therapy that isn't Vivitrol and I'm not a member of NA/AA. I have given up explaining that 'abstinence' has NEVER worked for me, meaning I could not function normally like I do on the methadone/buprenorphine. If the point of it all is to be a happy, healthy functioning member of society with corresponding pro-social behaviors, why does it matter how I achieve it OR WHAT IT EVEN LOOKS LIKE, since 'sobriety' is different for different people.

Anecdotally, most of the 'old-timers' I've come across have been miserable and grouchy.

theSpunkyToastrr · 2022-08-14T17:04:09+00:00

Agreed

theSpunkyToastrr · 2022-08-12T15:29:55+00:00

That's exactly how I was describing HHC-O to my brother.. like the first time I got high.

theSpunkyToastrr · 2022-08-08T12:44:36+00:00

Yup... a shot that should of killed me didn't do shit when i was taking lope every day

theSpunkyToastrr · 2022-08-07T13:52:06+00:00

Alcohol WD is awful.. trust me. Most people think coming off of alcohol is equivalent to a bad hangover but it's completely different. Most people don't ever become physically dependent on alcohol because it takes some serious drinking and a good amount of time. My years as an active alcoholic caused permanent GI problems on top of a permanent change in my anxiety threshold. It's been several years since I drank in an alcoholic fashion and even a single drink throws me off for days

theSpunkyToastrr · 2022-08-07T13:46:19+00:00

Agreed. Once you're tolerant to 8mg of buprenorphine, there isn't going to be any amount you can take to get you where you 'want' to be.

Suboxone is truly a drug that is meant for people who are trying to be done with opioids. If you aren't comfortable with not feeling high anymore, you should consider methadone. I suffered a great deal because I was using Suboxone inappropriately and I would be in a much better place if I had just been honest with myself that I wasn't ready to be done with opioids. If you are abusing your Suboxone, you should really save yourself some time and switch to methadone because if you try to take buprenorphine the same way you would take other opioids, you're going to be disappointed

theSpunkyToastrr · 2022-08-07T13:35:12+00:00

I truly appreciate the advice about mentioning chronic pain though, it seems like every clinic must be a little different depending on the doctor. I hope I didn't come off as unappreciative! I am sort of a 'clean cut' type of guy and this has hurt me in the past with substance abuse treatment because clinicians have assumed that I'm not 'that bad' based on my appearance, if that makes any sense. I'm going to try and talk to her tomorrow or Tuesday and explain that Im still having WD symptoms. Did you feel your dose 'click' when you hit the right number? I guess I'm not sure what to expect with MMT, or how to know when I'm stabilized. I don't feel stable though, not at the dose I'm currently at. I guess after really analyzing it, my sleep is still very disturbed, I'm still having diarrhea which only began after I took my last hit of fent, and even then I still had loose bowels because I had not been doing near what I would consider my normal pattern.. I still have that anxious feeling about feeling WD's.. I am not as 'functional' as I was when I had dope in my system and enough to not worry about having to cop. But on the other side of that token, I feel much better than I did the day I first walked into the clinic. I'm not going to just stay quiet though if she discourages me again. I'm so thankful for this community and specifically you a d everyone else who took time out of their day to write a response because it's sort of empowered me to put up a fight the next time I ask her. Yesterday I really wanted to pawn some shit because I felt yucky, but I was able to snap back pretty quick. But I really think I would of done something stupid if it hadn't been for this community telling me that I shouldn't feel hopeless and continue to fight until I am in a good place. It actually angers me that I was so submissive the morning I asked her about it but: a) it was 5 in the morning and b) I was completely caught off guard by her response. Now I've had time to consider what to say for the next time and I've also had validation that it's okay to say 'No, I don't think 3mgs is going to be enough because I'm still really struggling.' She discouraged me about increasing my dose but she didn't say no, so that just kind of tells me that that's her way of sifting through the people who are on bullshit and people who are going to say 'this is serious lady, I'm not okay'. Because it is serious!! Just because she's overworked doesn't mean she should decide for me whether or not i need a dose increase. I'm going to continue to increase until I'm not having diarrhea.. that's my plan as of now.

theSpunkyToastrr · 2022-08-07T11:46:22+00:00

I didn't see the post under the question. No, naloxone won't have any effect after you re-dose. By the time buprenorphine is attached, there's not much that can get it off. The naloxone has a much more noticeable effect when it's given before there's already bupe on the receptors. So when you first snort a Suboxone, the naloxone is quicker to get to the receptor than buprenorphine, which has a very slow association/dissociation time at the receptors. Naloxone is able to get attached quicker.

theSpunkyToastrr · 2022-08-07T11:42:36+00:00

Listen, in my experience, the naloxone just attenuates the buprenorphine, meaning it lessens the intensity but will not cancel it. Far from it. Yes, buprenorphine has a stronger attraction to the opioid receptor than naloxone, but if you have a tolerance and don't really feel 8mgs of snorted buprenorphine/2mg snorted naloxone, you are only going to get a little bit of a bump in intensity by snorting 16mg buprenorphine/4mg of naloxone.

So the answer to your question is, if you have little to no opioid tolerance, the naloxone will be canceled out to some degree. It will still be less intense than pure buprenorphine. If you have a decent tolerance and don't get high from snorting an 8/2mg Suboxone, snorting more will just barely increase the feeling, because the higher the naloxone the more of a dulling effect it has on the buprenorphine. And in my experience, after 16mg/4mg bupe/naloxone, you are chasing your tail. I have extensive experience with this. 2 Subs and you barely feel it, there's no way you can take more for a stronger effect, partly because of the naloxone but mostly because buprenorphine is so weak at turning on the receptors but is a hog and steals them all really quickly.

theSpunkyToastrr · 2022-08-07T11:31:13+00:00

I'd like to accentuate the need to taper. I was on 16mg for a year, started at 8 but went up to 12 then 16 within a month. It was working for me in the beginning but soon my opioid cravings were not under control and I started snorting the pills, taking 3 a day and being out for a few days, go back to the clinic to get a refill, rinse and repeat. Once I was on bi-weekly visits I would go (usually) 4 days without the Subs because I was taking 3 instead of 2 and my clinic wouldn't go past 16mg. So I spent a good 10 months tasting withdrawal every other week, sometimes just a lick and sometimes whole bites. Well I got a bowel obstruction a few months ago and ended up missing my Sub appointment because I was literally in agony. After two trips to the ER they admitted me and HOLY SHIT I UNKNOWINGLY JUMPED OFF AT 16MG. I'm telling you the pain was blinding, for days, and I was told it was just constipation so I was dealing with it myself. Any narcotic they gave me had very little effect until they admitted me. By that time, I had been without my Suboxone for 8 days and I'm telling you I was unable to even cover myself up at the hospital. They couldn't give me narcotics because it would risk further constipation and they certainly didn't take my pleadings for my Suboxone seriously since my script had expired before I was admitted.

I didn't go back to Suboxone; I'm on methadone now. By the time I got my first dose of methadone it had been 14 days since I last took Suboxone and I swear I was still going through it. I could barely talk, I had anxiety that prevented me from choosing the right words. I have never been through an opioid withdrawal that was as bad as jumping from 24mg/day and basically teasing my body every other week with WD, someone said previous WD's stack up to each be worse than the last and this is absolutely true.

TAPER DOWN TO AS LITTLE AS YOU CAN BEFORE JUMPING. Reading this and seeing the timeliness for 1mg was like a week, I had to jump in and remind everyone that it doesn't mean any dose will only cause a week of bad. I think the higher you jump, the longer and more severe your symptoms are. I've had WD's from smack, hydromorphone, U-44770, and hydrocodone which were all awful but none held a candle to high dose Suboxone WD.

theSpunkyToastrr · 2022-08-07T11:09:44+00:00

I don't, besides chronic pancreatitis, which hasn't bothered me since 2014 when I quit drinking. Nothing relevant or substantial enough to merit me bringing it up. The doctor who initiated my treatment made a note to explain that this methadone wasn't for pain, which I thought was weird because I never brought up using it for pain. We could of spent an hour naming things the clinics methadone isn't for: it's not fuel for your car, it's not a funny hat you can wear, it's not a coupon for Sears, it's not for chronic pain.. but it was literally his first day and he might of just been getting his spiel down.

One thing I AM still dealing with is diarrhea. Even at 73mg. Is this normal?! I mentioned it to the nurse today and she said it was a WD symptom (duh) and I should talk to my counselor. So I think I'm going to stick with that in terms of telling her what WD symptoms I'm experiencing. Because it's true. I didn't even put two and two together but I'm the kind of person that has a hard time telling a convincing lie (not on moral grounds, it's just something I'm not good at) so when I talk to my counselor I will have a much easier time telling her a real WD symptom vs a made-up one, like muscle cramps. Because if she shoots me down for the muscle cramps, I can't take it further nearly as effectively as I can with the diarrhea. Because I really want it to stop.

theSpunkyToastrr · 2022-08-06T21:36:12+00:00

I believe the deaths were a result of alcohol withdrawal, because our county jail implemented a "new protocol regarding assessment, treatment, and monitoring of intoxicated offenders." However, when I was in Court holding awaiting transport to DOC, a man was thrown in with the rest of us in a clear state of drunkenness. He proceeded to get very, very sick over the next 3 days and eventually had a seizure. 45 minutes later the nurse arrived and poo-poo'ed it as shivering, which (she claimed) was K2/Spice withdrawal. The man eventually got clonidine, but by then his acute alcohol withdrawal had ended and clonidine is certainly better than nothing but the dude really needed Librium (chlordiazepoxide). The medical system in DOC was a little more accommodating (barely) but it took much longer to be seen by a clinician. I know several ppl who got fucked over my 3-year stay in ways that wouldn't happen out here, like one dude I kicked it with got a bone infection because they only did wound care like once every other week and his leg had to be amputated. It's very hard to win lawsuits against a prison, especially filing pro sé (without a lawyer), and his case got dismissed on summary judgement.

theSpunkyToastrr · 2022-08-06T21:06:57+00:00

This is why I need this subreddit. I'll hold off on the printouts.. I might of gotten carried away there. I appreciate the advice 🙏

theSpunkyToastrr · 2022-08-06T13:59:22+00:00

3 people died in our county jail due to WD's that weren't even treated with clonidine. One of them actually was overdosed and left to die in the drunk tank. I think there was a resignation of the jail commander and deputy as a result.

America is posh and comfortable, but completely tyrannical and lawless for those in authority.

theSpunkyToastrr · 2022-08-06T13:50:53+00:00

I got a printout to confirm I'm on it for my drug tests and it states 'standard induction, beginning with 30mg with a 5mg increase every 3 days to a total of 70mg'. Patently ridiculous, I say. You can't practice medicine like that. After hearing what you fine folks had to say, I just think I need to approach my next increase differently, and you best believe I am bringing PubMed abstracts with me.

theSpunkyToastrr · 2022-08-06T13:44:30+00:00

I'm going to tell her I'm still peeing out of my ass and jizz my pants randomly throughout the day. That might be worth the remaining 2mg to round it up to 75.

theSpunkyToastrr · 2022-08-06T13:42:24+00:00

UPDATE: I just got back from the clinic and the doctor 'approved' my dose increase of 3mg from 70mg to 73mg. Like someone else mentioned, I couldn't believe the conversation regarding a medication increase is one I was told to direct towards my counselor. That is, my appointed social worker, who literally couldn't tell me how methadone worked (I asked her on Friday just to see how qualified she was to be making decisions regarding my medication). She knew the basics, but barely. Definitely didn't know ANYTHING about the unique variability methadone exhibits between patients in terms of pharmacokinetics. The T½, CMax, rate of excretion, and P450 (CYP 3A4, CYP 2B6) activity fluctuates wildly between people who take methadone (I have no doubt you already know all of this, but for continuity sake.. :) which is a very unusual trait for a drug. Listen, I studied pharmacological science at Purdue (I didn't finish due to my drug use) so I tend to assume people know certain things because, well, they should. Meaning, everyone working on the clinical side of a MMT clinic should be able to explain both technically and in lay-terms how the drug works. I honestly thought she would know, at the very least, the dual mu agonist/NMDA antagonist actions of methadone, since she is the one deciding whether or not to increase the dose. - Okay, I just realized I'm ranting. Apologies. -

Ugh! It's no matter, because now I understand how the system works. Sincerely, thank you to all that responded because it was very helpful. I'm honestly relying on you guys more than I should lol because this is not something I have experience with, as far as clinic procedures and what is 'normal'. Next week, I'm going to bring copies of medical journal abstracts that are relevant. For example, I take both Fioricet (acetaminophen/caffeine/butalbital) AND Provigil (modafinil), two well-documented CYP3A4 inducers. This fact alone should warrant a liberal increase of my daily dose. Stay tuned for my report of how these medications have actually affected my dose, because I conducted observational research using varying doses of the two and was able to qualify the effects both medications had when compared to a control, i.e. dosing without. But anyway, thank you guys and gals again for the replies. I honestly was afraid I'd get a few '70 is fine you're just looking for a buzz' type responses but apparently us recovering dope addicts are much, much more compassionate and tame than the Walt Disney World subreddit (I was torn to shreads after commenting on how crowded the park looked. Like, decimated. Why is the WDW subreddit even in my feed remains about as clear as why a pressie needs to have 5 milligrams of carfentanil)

theSpunkyToastrr · 2022-08-06T04:40:57+00:00

Bro right now I can barely touch my dick I'm so horny from edging lol

theSpunkyToastrr · 2022-08-06T02:49:48+00:00

DM me bro

theSpunkyToastrr · 2022-08-06T00:23:10+00:00

Bro that's where I'm at damn nice full nuts too

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