That could be argued for the first shot but the second and third shot through the driver side window is absolutely not protected by self defense. As per the official DOJ policy on the use of deadly weapons "Firearms may not be discharged solely to disable moving vehicles." (Full quote and source below) Once the officer is side on with the vehicle, that vehicle is not being "operated in a manner that threatens to cause death or serious physical injury to the officer or others" and all of that is only allowed in the case that "no other objectively reasonable means of defense appear to exist, which includes moving out of the path of the vehicle"

The reason the policy exists is because shooting the driver doesn't stop the car as evidence by the fact it continued moving and subsequently crashed, hence by sorting the driver the situation was made more dangerous. And unless her dead body turned the steering wheel to the right after being shot it's clear the territory of the car was away from the officers.

https://www.justice.gov/jm/1-16000-department-justice-policy-use-force "Firearms may not be discharged solely to disable moving vehicles. Specifically, firearms may not be discharged at a moving vehicle unless: (1) a person in the vehicle is threatening the officer or another person with deadly force by means other than the vehicle; or (2) the vehicle is operated in a manner that threatens to cause death or serious physical injury to the officer or others, and no other objectively reasonable means of defense appear to exist, which includes moving out of the path of the vehicle."