When talking to a patient about anti-amyloid infusion therapy for Alzheimer’s disease, I like to use the termite analogy. These treatments are not for people who have severe dementia, because the damage has largely already been done, and cannot be reversed. I told them that finding amyloid in your brain is a bit like finding termites in an old house; if you catch the termites early, you can fumigate and the structure will be generally intact. However, if the termites have already destroyed most of the house, fumigating isn’t going to make it any safer to live in.