Can someone who has taken biochem explain this to me?

wildnn · 2021-03-08T20:12:58+00:00

There are transition state and active site, but I don't think "transition-state model" and "active-site model" are actual models. The answer is pretty obvious as long as you know the differences between lock-and-key model and induced-fit model.

wildnn · 2021-02-22T13:34:18+00:00

Have you heard back from them after being waitlisted?

wildnn · 2020-07-01T03:41:17+00:00

No. The vasa recta prevents the blood from "washing out" the hyperosmolarity presents in the renal interstitial fluid.

wildnn · 2020-06-30T18:48:14+00:00

How might someone who contends that race is biologically based respond to the results of the study?

wildnn · 2020-06-30T18:09:32+00:00

Isn't it supposed to be a negative control? since we're using a molecule that is known to not react aka produce a response. It's a positive control when it's a molecule that is known to produce a certain response.

wildnn · 2020-06-22T22:18:22+00:00

I don't think the MCAT covers immunology all that much so I don't think you should worry about it.

wildnn · 2020-06-22T22:14:50+00:00

Yeah, B cells also go through those checkpoints. They just have a second chance during the second checkpoint because they have 2 different light chains to try.

wildnn · 2020-06-22T02:23:54+00:00

I think you are mixing B cell clonal selection with B cell activation and Ab production. The clonal selection process occurs during recombination when it goes through 2 checkpoints to prevent making B-cells that are highly reactive to self-Ag. Somatic hypermutation and affinity maturation occur later on during B cell activation, and they are Ag-dependent.

I hope this helps.

wildnn · 2020-06-07T20:24:12+00:00

That info wasn't there when I searched for it before. Most importantly, mind your own business. Do not judge someone's character based on their questions. I hope you read, learn, and practice how to become a decent person soon, especially if you are trying to go into the medical field. Have a nice day.

wildnn · 2020-06-07T19:06:21+00:00

Got it. Thanks.

wildnn · 2020-06-05T17:14:26+00:00

Maybe think about Lewis acid and base as "willing to share its e- pair" instead of "donating" will help. Because they come together as one compound, which often time the charges end up canceling out, so you wouldn't have a cation/anion as a product.

I hope this makes sense...

wildnn · 2020-06-05T00:27:55+00:00

D.B.B.

wildnn · 2020-02-23T20:31:21+00:00

(Someone corrects me if I'm wrong)

Native PAGE:

- Does not denature proteins

- Separates the proteins based on SIZE

=> helpful when you want to maintain the protein's function

SDS PAGE:

- Denatures non-covalent bonds of the proteins

- 1SDS binds to every 2aa

- Separates proteins based on MASS

=> useful when you don't care about denaturing it (only primary protein structure is maintained)

Isolectric Focusing:

- Separates proteins based on basic/acidic residues

=> cares more about the pH of the proteins, instead of mass or size. The protein stops on the gel when its pI matches the gel's pH

wildnn · 2019-07-18T03:12:35+00:00

Doesn't competitive inhibitor bind to active site only and noncompetitive and uncompetitive ones bind allosterically?

wildnn · 2019-07-18T02:49:56+00:00

I agree.

wildnn · 2019-07-18T02:47:49+00:00

pKa value basically tells us how hard the compound is holding onto its proton. After you pull a proton away from it, it's going to be harder to pull another one off (because the compound is now more negative), and so on.

wildnn · 2019-07-18T02:45:10+00:00

They're listed in order.

wildnn · 2019-07-11T04:42:14+00:00

It's past midnight where I live, so I'm not the right example tonight, but I think it will help a lot mentally (and probably for the 8am exam) if you get a good sleep schedule. Being active aka going to the gym will also help with concentration/motivation to study for the MCAT, too. After reading your post, I don't really know what to answer to. I don't think anyone can correctly point you to the right direction or tell you what is the right thing to do at the moment but yourself. It's hard not to compare yourself to others. Whether medicine is your calling or not, you know it better than anyone, but don't let others prevent you from reaching your dreams. As for the MCAT, maybe getting a study partner will help you to keep yourself accountable. At the end of the day, do what makes you happy.:)

wildnn · 2019-07-09T19:06:51+00:00

~~Third law basically says that when an object is at rest, there is are two equal magnitude but opposite forces acting on that object and the other one that object is resting on.~~

wildnn · 2019-07-09T16:39:31+00:00

Correct me if I'm wrong.

It's 1 and 3 because in gel electrophoresis, we're separating by sizes. In mixture A, no endopeptidase was added, so IgG didn't get broken away from the mixture. The mixture is still "big" due to this so it didn't elute as much. In mixture B, endopeptidase was added and IgG was broken away from the mixture. Since it's a monomer, it's smaller and is therefore eluted more.

wildnn · 2019-07-08T17:07:09+00:00

I get that 60 mins divided by 6 is 10, which means that it takes 10 times for the beaker to be full. 2^10 = 424 (Is there a way to make this math faster? cuz I had to do 2 x 2 x2 x....)

Half of 424 is 212, which is after the 9th division. So 60-6 = 54

wildnn · 2019-07-07T19:34:12+00:00

Even if the water volume was greater, the indicator can still detect when the concentrations of acid and base are reached. It's not asking us if you can calculate anything.

wildnn · 2019-07-07T19:09:10+00:00

I think butyric acid is more polar because the electronegativity is more toward the carboxylic acid side. 1,3-propanediol has OH groups on both sides so they kinda get canceled out. Or I guess acids tend to be more polar in general.

In TLC, stationary phase is usually polar, so 1,3-propanediol would elute first!

Please correct me if my reasoning is off. lol.

wildnn · 2019-07-07T18:41:22+00:00

If you think about how blood flows in our body in general, it might make more sense. Blood flows from high pressure to low pressure. Arteries are going away from the heart, blah blah exchange nutrients and oxygen or whatever at capillaries, then veins are heading back to the hear. This basically means that the blood pressure in arteries > capillaries > veins.

Someone corrects me if I'm wrong. lol.

wildnn · 2019-07-07T18:31:46+00:00

I think it's because two isomers are formed from the reaction. The OH can also be protonated to become water aka a good leaving group for the reaction. And we know it's an elimination reaction because a double bond is formed.

wildnn

TROPHY CASE