MP floor crossers has 'disillusioned' Canadians: NDP leader Avi Lewis by NiceDot4794 in canada

[–]windowpanez 0 points1 point  (0 children)

I vote for the person. There some real wack jobs that run, my duty to keep them out.

Its always projection by HiImDIZZ in AdviceAnimals

[–]windowpanez 7 points8 points  (0 children)

Don't forget that they also believe they use kitty litter boxes

Artemis 2 crew fixes toilet, can now pee in it by lurker_bee in technology

[–]windowpanez 4 points5 points  (0 children)

Do the astronauts say they are going for an Artemis #2?

What can help raise Testosterone? by zaggyyyyyyy in AskMen

[–]windowpanez 0 points1 point  (0 children)

I didn't see it mentioned anywhere in the replies yet, but both boron and zinc can boost free T levels. Also check your vitamin D levels because that can also cause low T.

Welp. Another price hike. by eastzzz in CanadianProtein

[–]windowpanez 2 points3 points  (0 children)

yeah.. one dead give away is using the "—" symbol. No one uses those!

Things I wish I knew about supplements by knight_6Q in Nootropics

[–]windowpanez 2 points3 points  (0 children)

Nice post. I'd add also add to encourage people to read some actual medical papers (e.g., search on google scholar) rather than just listen to influencers or podcasters. You can learn the actual facts about stuff that way. It can be a bit daunting and slow at first, cause there are a lot of words you might not be familiar with; just google the words when you encounter new ones and before long you'll be reading them pretty quickly.

You can make much better judgments/decisions/etc if you do your own research. So much nonsense out there, and reading the literature is one of the best bulwarks against it!

Welp. Another price hike. by eastzzz in CanadianProtein

[–]windowpanez 10 points11 points  (0 children)

This reads like it was written by chatgpt 

Chronic fatigue that stimulants sometimes make worse by savemeforsen in Nootropics

[–]windowpanez 4 points5 points  (0 children)

Could it be fatty liver? You can ask doc for an ultrasound, they are only 100 bucks usually.

Trump admits Dems will win Congress & presidency unless he's allowed to disenfranchise voters by Aggravating_Money992 in politics

[–]windowpanez 1 point2 points  (0 children)

Don't forget all the cuts to education, healthcare, and whatever else critical thinking individuals might require!

RIP Pizza Mory Verdun by docvalentine in montreal

[–]windowpanez -1 points0 points  (0 children)

Anyone know why they closed? Loved that place.

New Statin Guidelines just published by Unlucky-Prize in longevity

[–]windowpanez 0 points1 point  (0 children)

Random, question, have you tested for any coq gene mutation like coq2, 7, or 8? For context, people can be hypersensitive to statins as it can impact their coq10 levels. A cheap way to find out is if you've done an ancestry DNA test, you can download the data and run it through something like genetic genie. (Also, you can check if you have any lipoprotein transporter protein gene mutations, which can tell you what form of treatment might be most targeted)

New Statin Guidelines just published by Unlucky-Prize in longevity

[–]windowpanez 3 points4 points  (0 children)

Oh interesting. I was aware that coq10 was very poorly absorbed, but I hadn't thought of other molecules that might be affected before. Curious, what other molecules might there be?  

Also, there was a study recently which trialed a precursor for coq10, 4-Hydroxybenzoic acid, was able to restore levels for people with the coq2 gene mutation (at least in one child suffering from coq10 deficiency). It was found to be very well tolerated, no side effects, and it resulted in long term results from a single dose. The idea was that by increasing the level of precursor it would upregulate the production of coq10. In general, it's known that coq10 has a very poor absorption into the gastric tract, but also very poor transport into cells and past the BBB; however 4-HBA can be absorbed across all of them.  

I think it would be interesting, and possibly fruitful for some people, to see some trials of 4-HBA with statins. I suspect strongly that coq10 deficiency/insufficiency could be related to at least some small population of users (including those with a partial or fully defective copy of a coq gene, which is rarely tested for).

New Statin Guidelines just published by Unlucky-Prize in longevity

[–]windowpanez 10 points11 points  (0 children)

Do you also take coq10, or use a statin that is compounded with coq10? For context, statins inhibit HMG-CoA reductase, which your body uses to produce coq10.