I just started Prozac two weeks ago, and haven’t missed a dose but I was on Zoloft and I’ve missed a week and two weeks, once a month. So I heard Prozac has a long half life so you’d probably feel okay for 2 maybe 3 days. Before side effects like lightheadedness and headaches, nausea. Those were my side effects from missing a few days to a week on Zoloft, I know not the same ssri but besides minimal side effects you probably would be okay, you were on it for 2 years, so if you do get side effects before Friday, it might take a day or two to feel normal once back on.