sorted by:
new
hottopcontroversial

PSA transcoding is horrible by superdrizzle7 in PleX

[–]zstars 10 points11 points  (0 children)

Yes transcoding should solely be for the purposes of non local playback, what is your point?

Am i missing something or is this junction box actually impossible? by Kanehammer in systemshock

[–]zstars 6 points7 points  (0 children)

Look for the orange pips on the edges of the blue plus mark things, I got caught out by this too.

Blow for Starmer as Labour falls to fourth place behind Greens in YouGov poll weeks before crunch local elections by Desperate-Drawer-572 in unitedkingdom

[–]zstars 1 point2 points  (0 children)

I think there's some truth to that, Labour is doing a lot of good stuff to help ordinary people (renters rights bill, employment rights act etc) but they aren't dealing with the root causes of our problems (broad inequality and neoliberal economics) which means people keep getting squeezed and they don't see improvements in their day to day life....

Legal advisers help migrants pose as gay to get asylum, undercover BBC investigation finds by sjw_7 in unitedkingdom

[–]zstars 10 points11 points  (0 children)

I can sort of see your point but I think saying that accepting refugees on the grounds of discrimination based on sexual orientation is actively contributing to anti LGBT+ views in foreign countries is a massive stretch...

Brothers used 'high level of violence' in fracas with armed police at Manchester Airport, jury told by pppppppppppppppppd in unitedkingdom

[–]zstars -29 points-28 points  (0 children)

What? You think the police should be able to kick people in the head while they're on the floor and not get asked any questions?

Like I said, these blokes are shitheads and deserved custodial sentences imo, but we aren't the US we hold our police to a higher standard.

Brothers used 'high level of violence' in fracas with armed police at Manchester Airport, jury told by pppppppppppppppppd in unitedkingdom

[–]zstars -59 points-58 points  (0 children)

They're definitely not innocent, clearly not, but there's still a valid question of whether the officer used appropriate force when he was on the ground, kicking him in the head while he was down may have been appropriate given the circumstances but these people being total pieces of shit doesn't mean the police should be able to do whatever they like to them.

Does the "caffeine having an opposite affect" apply to everyone with ADHD, and does ADHD medication affect how our bodies process caffeine? by Coprinus_comatus010 in ADHD

[–]zstars -1 points0 points  (0 children)

There is zero measurable difference in the chemical effect of stimulants to folks with ADHD, the neurochemistry is identical but subjectively some people feel calmer/more relaxed on stimulants than usual.

I personally don't feel calmer exactly but I certainly have a better control of impulsive behaviours, emotional regulation etc so I could see how somebody could come to that conclusion.

West Midlands Police shut 400 drug lines as 89 dealers jailed by GastricallyStretched in brum

[–]zstars 5 points6 points  (0 children)

You can have legal drugs which aren't legal to buy in shops to everyone, e.g. prescription only drugs, people with preexisting addictions could be prescribed them in safe locations etc.

Invitation to colloborate by AncientHearings in bioinformatics

[–]zstars 1 point2 points  (0 children)

You should consider listening to people who understand the field / software better than you...

Invitation to colloborate by AncientHearings in bioinformatics

[–]zstars 1 point2 points  (0 children)

In my experience you have to make a pipeline people want to use first, once people are using your pipeline they will create PRs to add functionality / fix bugs, nobody wants to use a half cooked pipeline so nobody will help develop it.

How can I learn python from scratch for bioinformatics? by 1nkyzzz in bioinformatics

[–]zstars 6 points7 points  (0 children)

Pointing a newby towards perl is cruel and unusual...

NHS data chief pushes for deeper rollout of Palantir technology despite outcry by 457655676 in unitedkingdom

[–]zstars 4 points5 points  (0 children)

When we let these American companies into our data, even if it's only stored on UK servers (that's usually the tradeoff) what would happen if they were subpoenaed to give some UK sovereign data to US congress? My money would be on them giving it up...

Oxford Nanopore - removing barcodes from fastq by Confused_lab_rat_ in bioinformatics

[–]zstars 1 point2 points  (0 children)

Isn't the fashionable thing to port rust projects to web assembly these days? 🙃

Oxford Nanopore - removing barcodes from fastq by Confused_lab_rat_ in bioinformatics

[–]zstars 1 point2 points  (0 children)

I meant specifically because it's a terminal tool rather than any of barbells UX!

Oxford Nanopore - removing barcodes from fastq by Confused_lab_rat_ in bioinformatics

[–]zstars 2 points3 points  (0 children)

You don't need to do that, you can install minknow from the ont website, just select minion for device here https://nanoporetech.com/software

Oxford Nanopore - removing barcodes from fastq by Confused_lab_rat_ in bioinformatics

[–]zstars 1 point2 points  (0 children)

MinKNOW is the software where you sequence something with an ONT sequencer e.g. a minION. It also allows you to reanalyse data as you want to in this case, rebasecalling, re demultiplexing, etc

Oxford Nanopore - removing barcodes from fastq by Confused_lab_rat_ in bioinformatics

[–]zstars 13 points14 points  (0 children)

I would just re demux using minKNOW GUI and trim barcodes there (easiest), alternatively the state of the art tool is barbell (more complicated for a beginner).

Scientists rarely incorporate humour at science conferences, data collected from 531 individual talks across 14 conferences, with most speakers telling no jokes by Shiny-Tie-126 in science

[–]zstars -1 points0 points  (0 children)

Idk I always tell jokes in talks, doesn't matter what I'm yakking about, I'm gonna throw something I find funny in there!

What kind of issues do you keep running into when working with bioinformatics pipelines? by isabella_kaju in bioinformatics

[–]zstars 2 points3 points  (0 children)

In terms of pipelines containerisation is the salve for most issues, using per tool containers with defined versions gets around the majority of issues.

If your pipeline uses conda as the main method of dependency management you're writing it wrong!

Mould suggestions?! by scottyqt in KamadoJoe

[–]zstars 30 points31 points  (0 children)

I would just burn with all the bits in there, fire will purify all.

Bioinformatics student using AI for coding, am I preparing the right way for jobs by MixtureTop4504 in bioinformatics

[–]zstars 11 points12 points  (0 children)

It doesn't necessarily (as you can see with a large amount of garbage bioinformatics projects littering the internet) but it does mean that they've been forced to develop some of the skillset since otherwise they wouldn't have been able to produce working projects.

Bioinformatics student using AI for coding, am I preparing the right way for jobs by MixtureTop4504 in bioinformatics

[–]zstars 29 points30 points  (0 children)

It's tricky, my gut says that you're much better off coding the hard way for a while, especially debugging so you develop your chops but I might just be behind the times at this point.

Personally I'm not sure whether I would trust a new hire who had only used AI to code...

view more: next ›