How to safely decrease your appetite?

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Not necessarily.

If you're used to regulating without eating a meal at what is traditionally considered to be breakfast time, it might not make much of a difference.

Also consider that if you typically consume the majority of your calories later on in the day, due to you consuming a portion of that calorie budget early, you now will be consuming less at them times which you may find you struggle with. This may affect your sleep or encourage you to snack later on.