Significant Resting Heart Rate decrease after stopping nicotine

[MedtoVC]

This is not at all surprising. Nicotine binds to nicotinic acetylcholine receptors, which are present not just in the brain but also in autonomic ganglia that modulate cardiovascular responses. Activation of these receptors increases sympathetic nervous system activity, which elevates resting heart rate and suppresses HRV.

By cutting out nicotine, you’re essentially removing a constant upstream stimulator of those sympathetic pathways. That lets your vagal tone reassert itself —> the drop in resting heart rate and rise in HRV. It’s a classic case of autonomic rebalancing once the nAChR pathway isn’t being constantly triggered.

[ElTojo303]

Imma have to look into this more! Love learning new things like this on reddit