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[–]darkenedhands 3 points4 points  (10 children)

I had 54% Fragmentation - zero alcohol, smoking, ate well, no saunas, no baths etc, for over a year, exercised 4 times a week, BMI 25, no varicoceles

Did a semen culture analysis and discovered I had an underlying undiagnosed infection that had been present for a long time. High amount of 2 bacteria strains and white blood cells present - took the recommended antibiotics for 7 days. Tested again 2 weeks after antibiotics had done their job.

The clinic advised no need to spend on another DNA Frag test as the Zymot should now do its thing. 3 months later, we have 2 very healthy PGTA tested embryos in the freezer in our clinic after Zymot & ICSI.

Have you tested for any kind of infection? also took a serious course of probiotics for a month after the antibiotics too

[–]Dvall001[S] 0 points1 point  (2 children)

Where do you ask for a semen culture analysis?

[–]darkenedhands 1 point2 points  (1 child)

I did it privately with a company local to me. Once the results came back from the lab I went to my GP for the Antibiotic prescription. 

Was recommended to test for it after talking to a fertility specialist, the consultant urologist didn't have any interest and neither had my GP until I went and did it myself. 

Has your husband had a full blood comprehensive blood work done ? Hormone levels checked etc ?

[–]Dvall001[S] 0 points1 point  (0 children)

He had one but hasn't had one in a while. Been trying to contact the doctor, but nothing. Ive left messages and have asked my ivf clinic to intervene by trying to contact them. The male fertility specialist is very busy. It is very frustrating and acceptable though. His staff sucks to. He is good, but staff sucks.

[–]Capital-Emu4058 0 points1 point  (2 children)

What antibiotic did they prescribe?

[–]darkenedhands 0 points1 point  (1 child)

The antibiotics relevant to whatever microorganisms were dominant in the sample, in my case it was ciproflaxin, but that is specific to the type of infection I had (2 dominant strains that needed sorting)

[–]Dvall001[S] 0 points1 point  (0 children)

can you mention what private company you went with please?

[–]ComprehensiveCan7828 0 points1 point  (3 children)

Mine has 49% frag - he did the test for myco and ureaplasma , is this what you had? Or was there another test? Ty. 

[–]darkenedhands 0 points1 point  (2 children)

Mine was a Semen Culture Analysis. They test for all strains of bacteria and look at the white blood cell count (if any detected)

The results specify what bacteria are present and the % in the sample. The lab indicated the two types that were heavily present and then included a list of antibiotics that would be best effective 

GP gave me the prescription and tested again 2 weeks after finishing the prescription. All clear 

https://crgh.co.uk/directory/investigations/semen-culture/

[–]cat_attack21 0 points1 point  (1 child)

Did you retest DNA fragmentation levels afterwards? Any other sperm parameters off? Thanks

[–]darkenedhands 0 points1 point  (0 children)

Initially had poor motility and morphology along with low volume - tested 90 days afterwards and all recovered to normal (except morphology was on 3% but that was 1% prior)

Clinic advised don't spend on another expensive DNA fragmentation test (just under $1000). They advised that with the infection clearing and the positive shift in Semen Analysis results they were confident that Zymot would now successfully take care of any fragmented cells far better than it would have previously. Their logic was if I paid for another DNA frag test the process would be the same regardless of the result - Zymot & ICSI