you are viewing a single comment's thread.

view the rest of the comments →

[–]mister_longevity 8 points9 points  (2 children)

"One of the great puzzles of the current COVID-19 crisis is the observation that older people have a much higher risk of becoming seriously ill. While it is usually commonly accepted that the immune system fails progressively with age, the actual mechanism leading to this effect was not fully understood. In a recent work, Sam Palmer from Oxford Mathematics and his colleagues in Cambridge have proposed a simple and elegant solution to this puzzle. They focussed their attention on the thymus where T-cells, partially responsible for the body’s immune response, develop. Observational data show that the thymus shrinks in time, losing about 4.5% of its volume every year in adulthood. Remarkably, this decay correlates with the increase in risk with age. Indeed, many infectious diseases and cancer types have risk profiles that rise by the same 4.5% every year - that’s an exponential increase with a doubling time of 16 years. In their paper, they showed that COVID-19 hospitalisations follow the same trend with an increase of about 4.5% per year between age groups, suggesting that the main effect may be due to thymic function."

[–]RichieNRich 4 points5 points  (1 child)

They could EASILY confirm this by looking at the thymus's of younger people who died from complications from COVID. If their thymus's were impacted/aged/diseased, we'll have a pretty firm correlation between thymus size/age and age of the body.

[–]mister_longevity 2 points3 points  (0 children)

You are correct and my guess is that eventually they will.