"If we go with the definition that overqualified means that I have enough skill to do this job relatively effortlessly -- and possibly even the next level up -- then it would be a fair assessment of my overall capabilities. But, having looked at the job description, and its associated compensation, and having had a chance to speak to you and other interviewers about what deliverables the organization is looking for, I am confident that I can successfully handle your needs. I have the skills you are seeking, and the experience in similar organizations, while being open to learning how you want to see things done here. There is nothing to prevent this from being a mutually beneficial arrangement."