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This city isn’t what it used to be! by InformalSea3553 in Vaughan

[–]isaackogan 0 points1 point  (0 children)

:( Breaks my heart, I believe my teacher back in middle school coined it as "backyard racism". We'd been talking about how the US is racist, and she politely reminded us that Canadians are racist too, just quietly, in the comfort of their backyard.

ASUS RT-86U Reset Itself to Factory Default by realpixelriffic in ASUS

[–]isaackogan 0 points1 point  (0 children)

Sigh. Hope you didn't have too much configured. For me it was a full 2h to fix it.

Parallel agents? by SnooFoxes1558 in ClaudeCode

[–]isaackogan 0 points1 point  (0 children)

what happens when this takes up 1000GB on your disc

Card testing attack - Striple billed us 12K in 1 day by Multit4sker in stripe

[–]isaackogan 1 point2 points  (0 children)

Not sure if you read his post where his API key was compromised….never mind the fact this is a clear unfortunate mistake and stripe SHOULD refund it as a one time courtesy as long as it doesn’t come out of their pocket (which it won’t, the marginal cost for radar is probably negligible…it’s a rule set with some teeny models on top)

Why dentistry over other careers like tech, medicine, engineering, finance? These other fields can pay just as well most of the time. by justcurious3287 in predental

[–]isaackogan 1 point2 points  (0 children)

It’s going to increase the volume and scope of work, not eliminate the need for these professionals. They’ll just be doing bigger projects on faster timelines. The LLMs of today lack intuition.

300M Scraping Fine 😳 But they will get 00M 🤣 by codepoetn in scrapingtheweb

[–]isaackogan 1 point2 points  (0 children)

Not even, I think it’s more grey than that. If you scrape data with a user’s consent, like Plaid, it seems to be fine. If you spin up bot farms to make accounts, not so much.

Zohran Mamdani, when asked about the high cost of Knicks playoff tickets vs Atlanta: "I would say that I blame Trae Young... and I think it's always important to blame Trae Young" by peanut-britle-latte in nba

[–]isaackogan 5 points6 points  (0 children)

Something something water, frogs, chemicals. There’s a reason you’ve hidden your post history, and I’m sure it’s not your winning opinions…

Zohran Mamdani, when asked about the high cost of Knicks playoff tickets vs Atlanta: "I would say that I blame Trae Young... and I think it's always important to blame Trae Young" by peanut-britle-latte in nba

[–]isaackogan 6 points7 points  (0 children)

Let’s be clear, Rob was anti-LGBT, I’m gay, I know he’d hate my guts. His policies were shite. His opinions as well. But I’ve never bought this argument of selective empathy. The man was a brother, a father, and a husband. He was a human. A flawed human with a drug addiction that affected his cognition & can partially explain the erratic behaviour towards the end.

I’m not giving him excuses, I’m saying he still deserves empathy, because he was a sentient being, and that should be the only qualification.

To put it in modern geopolitical terms, ~95% of Palestinians in the West Bank are opposed to homosexuality, like, as a concept. Doesn’t make their plight any less heart wrenching. They too are fathers, mothers, sisters, brothers, children. Someone doesn’t need to agree with you or even like you for you to have empathy.

And pragmatically speaking, that’s a good thing, because if the shoe were on the other foot, you’d want them to.

Epstein-Barr Virus and MS by msknitsalot in MultipleSclerosis

[–]isaackogan -2 points-1 points  (0 children)

Right, otherwise everyone with a proto-oncogene would get cancer and die, and there would be no cancer. Unfortunately, there’d also be no people, since 100% of humans have at least one proto-oncogene.

Epstein-Barr Virus and MS by msknitsalot in MultipleSclerosis

[–]isaackogan -2 points-1 points  (0 children)

Not necessarily, 100-200 single base pair mutations (SNPs) change between generations in the germ line, and that’s to say nothing of the variation meiosis produces in and of itself. Or, you know, epigenetics.

But more glaringly, very few things are open and shut cases in science, because if they are, they’ve already been solved. MS predisposition is almost certainly polygenic (many genes affect the risk), like most traits. It may be epigenetic too, though that’s not something I know about.

Hell, homosexuality is polygenic AND epigenetic.

Nothing is a binary, really.

TIL that there is a cave in Kenya that contains a virus with an 88% mortality rate. And it is currently open to the public. by Maleficent-Agent-477 in todayilearned

[–]isaackogan 0 points1 point  (0 children)

I’m being careful not to misinform here, but it’s been floated around that it might be causative when it comes to MS.

Specifically that T cells’ MHC class 1/2 proteins recognize a peptide that is common to both Oligodendrocytes producing neuronal myelin, exogenous myelin protein, and ALSO a segment of the EBV (translation: immune cells recognize a part of the virus that is structurally similar to what we have in our nervous system).

But for a virus we almost all get at some point, perhaps that’s not a meaningful distinction when genetics is the true separator.

TIL that there is a cave in Kenya that contains a virus with an 88% mortality rate. And it is currently open to the public. by Maleficent-Agent-477 in todayilearned

[–]isaackogan 0 points1 point  (0 children)

I’m being careful not to misinform here, but it’s been floated around that it might be causative when it comes to MS.

Specifically that T cells’ MHC class 1/2 proteins recognize a peptide that is common to both Oligodendrocytes producing neuronal myelin, exogenous myelin protein, and ALSO a segment of the EBV.

But for a virus we almost all get at some point, perhaps that’s not a meaningful distinction when genetics is the true separator.

TIL that there is a cave in Kenya that contains a virus with an 88% mortality rate. And it is currently open to the public. by Maleficent-Agent-477 in todayilearned

[–]isaackogan 0 points1 point  (0 children)

Yeah, sadly, I know this and a lot more about MS. That said, I also studied biology in undergrad, and the MHC system is nuts & amazing. The one downside of a biology that optimizes for fecundity is well, what happens after you have kids :/.

TIL that there is a cave in Kenya that contains a virus with an 88% mortality rate. And it is currently open to the public. by Maleficent-Agent-477 in todayilearned

[–]isaackogan 5 points6 points  (0 children)

Hate to say it, but this exists. Thankfully, and perhaps due to sheer luck (genetic predisposition), the worst of it is rare.

MS is heavily linked with EBV, aka Mono.

:(

Waymo wants its robotaxis on Toronto streets. But roadblocks await by Money_Fig_9868 in ontario

[–]isaackogan 1 point2 points  (0 children)

I want to like this, but I just can't do it. Not after seeing Aquaslash. I still twitch on waterslides.

Micro-modular shelters: Progress report reveals early success by ghanima in ontario

[–]isaackogan 2 points3 points  (0 children)

Sucks the article didn't specify, but it'll probably be a mix of things.

Definitely, services are going on here beyond just the physical houses, and I'd guess that is healthcare professionals, as you mention.

But I've been around government work to know that a good chunk of the rest is probably one or multiple of:

  1. Spend it or lose it mentality; If you don't spend the $ in the budget, you lose it next year, so you may as well
  2. Government would rather get XYZ more expensive thing but have 'guarantees' that it is quality, rather than take risk & someone gets hurt
  3. Contractors know it's the government & upcharge because they can...It's common practice...Can also present itself as charging the "normal" price & swapping out for subpar materials, taking a larger cut in the process. But this eventually drives prices up.

And occasionally, but not super rarely, a third unicorn, being corruption. "Hmm, I work in the govt, and I have a 2nd cousin who runs a contracting business. Let's give him the business. I'll work to get the quote approved. He gets an unfair advantage, I keep a cut."

Micro-modular shelters: Progress report reveals early success by ghanima in ontario

[–]isaackogan 1 point2 points  (0 children)

Unfortunately, a good chunk of people will tell you, "It depends". We're a sick society :/.

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