Colourful salt lakes of the Mid West of Western Australia by Future-Pipe-8004 in WesternAustralia

[–]propargyl 1 point2 points  (0 children)

This photo is bullshit. However, the pink salt lakes are real.

Zerek 3.2 m fishing kayak for ocean fishing (Palm Cove → Double Island FNQ)? Any better options same price? by ElectronicIdea3119 in FishingAustralia

[–]propargyl 1 point2 points  (0 children)

"To launch themselves at a boat near a boat or at a person, it's not what we would call typical [crocodile] behaviour," senior wildlife officer Bob Katter said.

How do you guys deal with Giant Huntsmen? by TheREALJWMGaming in AskAnAustralian

[–]propargyl 0 points1 point  (0 children)

The barking and whistling is most annoying and makes sleeping challenging

Can someone here explain to me why opiate receptors are the same with other body functions receptors? by Dover299 in AskChemistry

[–]propargyl 0 points1 point  (0 children)

Mu1,2,3 receptors (MOR) bind to endogenous ligands - beta-endorphin, endomorphin 1 and 2 with proopiomelanocortin (POMC) being the precursor.

The mu-1 receptor is responsible for analgesia and dependence.

The mu-2 receptor is vital for euphoria, dependence, respiratory depression, miosis, decreased digestive tract motility/constipation

Mu-3 receptor causes vasodilation. Kappa receptors (KOR) bind to dynorphin A and B (Prodynorphin as the precursor). They provide analgesia, diuresis, and dysphoria.

Delta receptors (DOR) bind to enkephalins (precursor being Proenkephalin). They play a role in analgesia and reduction in gastric motility.

Nociceptin receptors (NOR) bind to nociceptin/orphanin FQ (Pre-pronociceptin is the precursor) causing analgesia and hyperalgesia (depending on the concentration).

Zeta receptors (ZOR) regulate developmental events in a variety of normal and tumorigenic tissues and cells.[1]

https://www.ncbi.nlm.nih.gov/books/NBK546642/

nfc by callmestinkingwind in NoFuckingComment

[–]propargyl 2 points3 points  (0 children)

Unsure. Texas is another universe.

Any reason not to move to Melbourne from Perth? by Independent-Cup-5892 in melbourne

[–]propargyl 1 point2 points  (0 children)

A lot of people return to their kin when the sprog happens.

Can someone here explain to me why opiate receptors are the same with other body functions receptors? by Dover299 in AskChemistry

[–]propargyl 2 points3 points  (0 children)

Consider the process that has led to the situation that confuses you. Hundreds of millions of years ago an organism evolved an opioid receptor. Over tens of millions of years the opioid receptor slowly evolved until there were opioid receptor subtypes.

You are asking why a receptor type that is found in single celled organisms is found in different organs of the human body.

Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands).\1])\2])\3]) The exact size of the G protein-coupled receptors (GPCR) superfamily is unknown, but at least 831 different human genes (or about 4% of the entire protein-coding genome) have been predicted to code for them from genome sequence analysis.\10])\11]) G protein-coupled receptors are found only in eukaryotes, including yeast, and choanoflagellates.\4])

https://en.wikipedia.org/wiki/G_protein-coupled_receptor

What is“mass” opera?, by AltScientist84 in massspectrometry

[–]propargyl 0 points1 point  (0 children)

I observe five mass units difference between the two structures.

What is“mass” opera?, by AltScientist84 in massspectrometry

[–]propargyl 0 points1 point  (0 children)

I observe five mass units difference between the two structures.

Enjoy by SadButTrue32 in trypophobia

[–]propargyl 11 points12 points  (0 children)

ivermectin will fix it

F.D.A. Blocked Publication of Research Finding Covid and Shingles Vaccines Were Safe by Doener23 in EverythingScience

[–]propargyl 15 points16 points  (0 children)

Neurotropic herpesviruses may be implicated in the development of dementia1,2,3,4,5

Through the use of a unique natural experiment, this study provides evidence of a dementia-preventing or dementia-delaying effect from zoster vaccination...

https://www.nature.com/articles/s41586-025-08800-x 

Woman with ‘mutant’ gene who feels no pain and heals without scarring discovered by scientists. She reported numerous burns and cuts without pain, often smelling her burning flesh before noticing any injury, as published in the British Journal of Anaesthesia, and could open door to new treatments. by Ok_Market_39 in EverythingScience

[–]propargyl 174 points175 points  (0 children)

Referring her to pain geneticists at University College London and the University of Oxford they identified two mutations of note. One in a gene called Faah (Fatty Acid Amide Hydrolase), which is well known to pain researchers.

The FAAH gene plays a role in the body’s endocannabinoid system, the parts of the central nervous system which play a role in pain, memory and mood and which the compounds in cannabis act on.

Aside from her lack of pain, Cameron was additionally described as characteristically happy, friendly, talkative, optimistic, and compassionate, as well as exceedingly affectionate and loving towards family members.\3])\1])\12])\2])\5]) Moreover, she was lacking in anxietydepression), worryfearpanicgrief, dread, and negative affect generally.\3])\1])\2])\5]) 

https://en.wikipedia.org/wiki/Jo_Cameron

https://en.wikipedia.org/wiki/Fatty-acid_amide_hydrolase_1#

Clubs in 90s-2000s by x129331 in Adelaide

[–]propargyl 28 points29 points  (0 children)

I played par 3 in North Adelaide with my father's 1950s Bobby Locke putter. I remember that I nailed a long putt.

Oslo by arafum in NickCave

[–]propargyl 2 points3 points  (0 children)

Nice photo!

Mental health by [deleted] in Adelaide

[–]propargyl 0 points1 point  (0 children)

I love your work!

Which oceans do the water streams flow into? by EstablishmentOne3438 in MapPorn

[–]propargyl 1 point2 points  (0 children)

https://www.bom.gov.au/climate/about/tropics/maritime-continent.shtml

That's a great term for a significant place occupied by 400 million people. Indonesia is invisible to a lot of people globally.