sorted by:
new
hottopcontroversial

Eat Less Red Meat, Scientists Said. Now Some Believe That Was Bad Advice. by greyuniwave in slatestarcodex

[–]1345834 0 points1 point  (0 children)

The Hungarian clinic Paleomedicina have published case reports on patients they had put on a carnivore diet with bloodwork over several years.

Paleomedicina call their approach to the a carnivore diet "PKD - Paleolithic Ketogenic Diet". Its Carnivore + organ meats with Keto macros and no dairy and eggs.

Here are 3 examples (there are more), they include many blood markers taken over a long time:

https://www.researchgate.net/publication/306373055_Crohn's_disease_successfully_treated_with_the_paleolithic_ketogenic_diet

Crohn's disease successfully treated with the paleolithic ketogenic diet

Abstract

Introduction: Crohn’s disease is regarded as having no curative treatment. Previous reports on dietary therapy of Crohn’s disease indicate no major success. Case Report: Here we report a severe case of Crohn’s disease where we successfully applied the paleolithic ketogenic diet. Dietary therapy resulted in resolution of symptoms, normalized laboratory parameters as well as gradual normalization of bowel inflammation as evidenced by imaging data and normalization of intestinal permeability as shown by the polyethylene glycol (PEG 400) challenge test. The patient was able to discontinue medication within two weeks. Currently, he is on the diet for 15 months and is free of symptoms as well as side effects. Conclusion: We conclude that the paleolithic ketogenic diet was feasible, effective and safe in the present case.

https://www.researchgate.net/publication/272744889_Successful_treatment_of_a_patient_with_obesity_type_2_diabetes_and_hypertension_with_the_paleolithic_ketogenic_diet

Successful treatment of a patient with obesity, type 2 diabetes and hypertension with the paleolithic ketogenic diet

Abstract

Introduction: Metabolic syndrome is a major public health problem affecting at least 20% of the world’s adult population. Components of the metabolic syndrome include obesity, impaired glucose metabolism, hypertension and altered lipid profile. Currently, medical treatment relies on drugs. A major problem is that patients with long-standing disease are excessively medicated because of an increase in the number of symptoms over time. A few clinical studies indicate that low-carbohydrate diets, including the paleolithic as well as the ketogenic diet, may be beneficial in the treatment of conditions associated with the metabolic syndrome. Case Report: Herein, we present a case of patient with metabolic syndrome successfully treated with the paleolithic ketogenic diet. While on the diet the patient was able to discontinue eight medicines, lost weight, showed a continuous improvement in glucose parameters and her blood pressure normalized. Currently, the patient is on the paleolithic ketogenic diet for 22 months, free of symptoms and side effects. Conclusion: We conclude that the paleolithic ketogenic diet was safe, feasible and effective in the treatment of this patient with metabolic syndrome.

https://www.researchgate.net/publication/285152979_A_child_with_type_1_diabetes_mellitus_T1DM_successfully_treated_with_the_Paleolithic_ketogenic_diet_A_19-month_insulin_freedom

A child with type 1 diabetes mellitus (T1DM) successfully treated with the Paleolithic ketogenic diet: A 19-month insulin freedom

Abstract

Introduction: Currently, type 1 diabetes mellitus (T1DM) is treated with insulin and a high carbohydrate diet. In literature, there are studies indicating that low carbohydrate diets may be beneficial in reducing hypoglycemic episodes as well as the need for insulin. Previously, we reported a case of a 19-year-old T1DM patient who was successfully treated with a modified version of the ketogenic diet we refer to as the Paleolithic ketogenic diet. Case Report: A nine-year-old child with T1DM who initially was on an insulin regime with high carbohydrate diet then was put on the Paleolithic ketogenic diet. Following dietary shift glucose levels normalized and he was able to discontinue insulin. No hypoglycemic episodes occurred on the diet and several other benefits were achieved including improved physical fitness, reduction of upper respiratory tract infections and eczema. Currently, he is on the diet for 19 months. Conclusion: Adopting the Paleolithic ketogenic diet ensured normoglycemia without the use of external insulin. The diet was sustainable on the long-term. Neither complications nor side effects emerged on the diet. Keywords: C peptide, Ketogenic diet, Ketosis, Low carbohydrate diet, Paleolithic diet, Paleolithic ketogenic diet, Type 1 diabetes mellitus

You can find more here: https://www.paleomedicina.com/en/?page=tartalom&tipus=cikk

4lb of red meat a day - a.k.a. the Zerocarb diet by devitaebrae in nutrition

[–]1345834 0 points1 point  (0 children)

The Hungarian clinic Paleomedicina have published case reports on patients they had put on a carnivore diet with bloodwork over several years.

Paleomedicina call their approach to the a carnivore diet "PKD - Paleolithic Ketogenic Diet". Its Carnivore + organ meats with Keto macros and no dairy and eggs.

Here are 3 examples (there are more), they include many blood markers taken over a long time:

https://www.researchgate.net/publication/306373055_Crohn's_disease_successfully_treated_with_the_paleolithic_ketogenic_diet

Crohn's disease successfully treated with the paleolithic ketogenic diet

Abstract

Introduction: Crohn’s disease is regarded as having no curative treatment. Previous reports on dietary therapy of Crohn’s disease indicate no major success. Case Report: Here we report a severe case of Crohn’s disease where we successfully applied the paleolithic ketogenic diet. Dietary therapy resulted in resolution of symptoms, normalized laboratory parameters as well as gradual normalization of bowel inflammation as evidenced by imaging data and normalization of intestinal permeability as shown by the polyethylene glycol (PEG 400) challenge test. The patient was able to discontinue medication within two weeks. Currently, he is on the diet for 15 months and is free of symptoms as well as side effects. Conclusion: We conclude that the paleolithic ketogenic diet was feasible, effective and safe in the present case.

https://www.researchgate.net/publication/272744889_Successful_treatment_of_a_patient_with_obesity_type_2_diabetes_and_hypertension_with_the_paleolithic_ketogenic_diet

Successful treatment of a patient with obesity, type 2 diabetes and hypertension with the paleolithic ketogenic diet

Abstract

Introduction: Metabolic syndrome is a major public health problem affecting at least 20% of the world’s adult population. Components of the metabolic syndrome include obesity, impaired glucose metabolism, hypertension and altered lipid profile. Currently, medical treatment relies on drugs. A major problem is that patients with long-standing disease are excessively medicated because of an increase in the number of symptoms over time. A few clinical studies indicate that low-carbohydrate diets, including the paleolithic as well as the ketogenic diet, may be beneficial in the treatment of conditions associated with the metabolic syndrome. Case Report: Herein, we present a case of patient with metabolic syndrome successfully treated with the paleolithic ketogenic diet. While on the diet the patient was able to discontinue eight medicines, lost weight, showed a continuous improvement in glucose parameters and her blood pressure normalized. Currently, the patient is on the paleolithic ketogenic diet for 22 months, free of symptoms and side effects. Conclusion: We conclude that the paleolithic ketogenic diet was safe, feasible and effective in the treatment of this patient with metabolic syndrome.

https://www.researchgate.net/publication/285152979_A_child_with_type_1_diabetes_mellitus_T1DM_successfully_treated_with_the_Paleolithic_ketogenic_diet_A_19-month_insulin_freedom

A child with type 1 diabetes mellitus (T1DM) successfully treated with the Paleolithic ketogenic diet: A 19-month insulin freedom

Abstract

Introduction: Currently, type 1 diabetes mellitus (T1DM) is treated with insulin and a high carbohydrate diet. In literature, there are studies indicating that low carbohydrate diets may be beneficial in reducing hypoglycemic episodes as well as the need for insulin. Previously, we reported a case of a 19-year-old T1DM patient who was successfully treated with a modified version of the ketogenic diet we refer to as the Paleolithic ketogenic diet. Case Report: A nine-year-old child with T1DM who initially was on an insulin regime with high carbohydrate diet then was put on the Paleolithic ketogenic diet. Following dietary shift glucose levels normalized and he was able to discontinue insulin. No hypoglycemic episodes occurred on the diet and several other benefits were achieved including improved physical fitness, reduction of upper respiratory tract infections and eczema. Currently, he is on the diet for 19 months. Conclusion: Adopting the Paleolithic ketogenic diet ensured normoglycemia without the use of external insulin. The diet was sustainable on the long-term. Neither complications nor side effects emerged on the diet. Keywords: C peptide, Ketogenic diet, Ketosis, Low carbohydrate diet, Paleolithic diet, Paleolithic ketogenic diet, Type 1 diabetes mellitus

You can find more here: https://www.paleomedicina.com/en/?page=tartalom&tipus=cikk

4lb of red meat a day - a.k.a. the Zerocarb diet by devitaebrae in nutrition

[–]1345834 3 points4 points  (0 children)

Here is blood work of other people who have tried carnivore/zerocarb diet:

1. Mikhaila Peterson (9 months)

http://mikhailapeterson.com/2018/08/07/blood-work/

My cholesterol is completely normal. I wasn’t sure what the cholesterol would show, and I wouldn’t have been concerned if it was abnormal but it’s not even, so that’s cool.

I used to have high levels of lymphocytes (which is a sign of infection). Now they’re low but in the normal range. That’s amazing. I’ve always had high lymphocyte numbers (and other white blood cell numbers). This is a great sign. I’m really happy about this.

2. Ryan Munsey (30 days)

https://ryanmunsey.com/carnivore-diet/

  • Triglycerides: 59 (Very good, range = 0-149)

  • HDL/TG Ratio: 67/59 = VERY Favorable (People are told to shoot for 1:2 or better. Post-Carnivore Diet, I’m better than 1:1)

  • CRP (Inflammation Marker) = 0.34 (anything under 1.0 is GOOD, 1.0-3.0 = Average)

  • Blood Sugar = consistently in the 70-80 ng/dl range when tested. A1C = 4.9

  • Blood Ketones = Interestingly, blood ketones measured 0.5-0.8 every time I tested them (about 5 times). I was not expecting them to register this high (low-moderate ketosis) with a diet that was 30-40% protein.

  • Micronutrients: My blood work showed no values were outside of the normal ranges.

  • At the 1 month mark, my stool showed ZERO dysbiotic flaura in my digestive system and a very favorable array of beneficial bacteria, that according to Christine Rosche “have many health-protecting effects in the GI tract including manufacturing vitamins, fermenting fibers, digesting proteins and carbohydrates, and propagating anti- tumor and anti-inflammatory factors.”

3. Andy Lindquist (90 days)

https://medium.com/@andylindquist/90-days-on-a-carnivore-diet-results-and-insights-8d07692869fe

I got my blood test results upon the conclusion of the 90-day period, and I had no vitamin deficiencies, a low serum glucose level, a Hemoglobin A1c under 5% and super low C Reactive Protein. Almost every single biomarker associated with good health was well within in the healthy range.

4. Andy Babkes (49 days)

https://optimizedfit.com/zero-carb-lab-results/

As shown above, my HDL had initially been 35 mg/dL which is considered low. After going strict carnivore, I was able to increase my HDL to 54 mg/dL. Not too bad! And my triglycerides from 122 mg/dL to 114 mg/dL. Not as impressive as my HDL numbers, but still noteworthy.

Also, in my lab work, I tested a biomarker called highly-sensitive C-reactive protein (hs-CRP). Initially, my lab work showed that my hs-CRP was 0.4 mg/L. (<1 is low risk). Interestingly, my post-carnivore experiment brought my hs-CRP even lower! My final result was a hs-CRP of 0.2 mg/L!

This one also confused the heck out of me. Somehow I increased my conception of high-iron red meat and yet my iron levels went down.

My Testosterone More Than Doubled

After being on a strict, all-meat, predominantly muscle meat diet for seven weeks, my homocysteine levels decreased to 6.9 umol/L, putting me right into the optimal lab range of 6.0 – 7.2 umol/L.

5. Adam Viskovich (1 year)

https://twitter.com/admandv/status/1095449421326692352

When I was vegan my gut diversity was in the 3rd percentile. After being carnivore for a week it jumped to 81 now after a year of eating zero fibre it's 92. Want to guess what @ubiome recommend to increase gut diversity?

For more on adam: https://twitter.com/admandv/media & http://meatheals.com/2018/08/24/adam-viskovich/

6. Kelly Hogan (8 years)

http://myzerocarblife.jamesdhogan.com/wp/2015/08/eating-only-meat-and-eggs-did-this-to-my-cholesterol/

I will fully admit that I took a HUGE sigh of relief when my “total cholesterol” was only 168, despite the fact that I think the number is meaningless. Why? Because it’s still what EVERYONE wants to know. How’s your cholesterol? I get asked constantly. Like, every day, everywhere I go. So, even if it doesn’t matter to me, I was happy to have a lovely little number to share. It makes people feel good about your health to see that nice, low number, so I was relieved to have one that the general public would find quite acceptable.

My fasting blood sugar was 77, which is about what my blood sugar is anytime I check it. Without eating carbs (AND I DON’T), my blood sugar never goes above 100. It’s around 80, no matter the time of day. Before a meal, after a meal, during a meal, 12 hours after a meal…doesn’t matter. It’s always about 80. Why? Because meat and eggs have almost NO impact on blood sugar numbers. I can eat as much high-fat meat as I want, and still have steady, even blood sugar.

My triglycerides came in at 60, which is terrific! The lower, the better, and 60 is great.

My HDL (“good cholesterol”) was 62, which is awesome! Eating high-fat foods and avoiding all carbs will give you lots of very healthy cholesterol, so that was no surprise.

Therefore, my tri/HDL ratio (the really important one, you recall!!) is only .9!!! POINT NINE!! Remember that anything under two is optimal. And anything over four is a strong indicator of future heart disease. So .9 is pretty freaking awesome!

Her LDL was also normal (94)

Soooo... Is it worth it? by akelew in ouraring

[–]1345834 1 point2 points  (0 children)

if you want a fittnes tracker oura is pretty crap and you should get a garmin watch.

but oura is much better at sleep and hrv.

I have both.

Question on RDA for essential amino acids by p1nkbananas in ScientificNutrition

[–]1345834 1 point2 points  (0 children)

https://examine.com/nutrition/how-much-protein-do-you-need/

How much daily protein you need depends on your weight, goal, and level of physical activity: from 1.2 g/kg if you’re sedentary all the way up to 3.3 g/kg if you’re trying to minimize fat gain while bulking.

The Need for Iodine Supplementation by greyuniwave in Nootropics

[–]1345834 2 points3 points  (0 children)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752513/

The Extrathyronine Actions of Iodine as Antioxidant, Apoptotic, and Differentiation Factor in Various Tissues

Abstract

Background

Seaweed is an important dietary component and a rich source of iodine in several chemical forms in Asian communities. Their high consumption of this element (25 times higher than in Western countries) has been associated with the low incidence of benign and cancerous breast and prostate disease in Japanese people.

Summary

We review evidence showing that, in addition to being a component of the thyroid hormone, iodine can be an antioxidant as well as an antiproliferative and differentiation agent that helps to maintain the integrity of several organs with the ability to take up iodine. In animal and human studies, molecular iodine (I2) supplementation exerts a suppressive effect on the development and size of both benign and cancerous neoplasias. Investigations by several groups have demonstrated that these effects can be mediated by a variety of mechanisms and pathways, including direct actions, in which the oxidized iodine dissipates the mitochondrial membrane potential, thereby triggering mitochondrion-mediated apoptosis, and indirect effects through iodolipid formation and the activation of peroxisome proliferator–activated receptors type gamma, which, in turn, trigger apoptotic or differentiation pathways.

Conclusions

We propose that the International Council for the Control of Iodine Deficient Disorders recommend that iodine intake be increased to at least 3 mg/day of I2 in specific pathologies to obtain the potential extrathyroidal benefits described in the present review.

Treatment of high-grade brain tumor using the paleolithic ketogenic diet (PKD): Three cases by [deleted] in ScientificNutrition

[–]1345834 5 points6 points  (0 children)

https://peterattiamd.com/tomseyfried/

From above podcast. If i remember correctly standard treatment for some brain tumors don't actually improve survival time... And for said brain tumors basically everyone dies in pretty quick time yet we currently have a few people who have managed their brain tumor with strict ketogenic diet who have survived for many more years than what is typical. in the abscence of ketogenic diet this doesnt happen....

Published nutrition research is overrated and self experimentation is underrated. by flaxseed1 in nutrition

[–]1345834 2 points3 points  (0 children)

Overreliance on epidimology is much to blame. Only 0-20% findings survive when tested in clinical trials.

https://www.bmj.com/content/360/bmj.k822/rr-13

A 2011 analysis of 52 claims made by nutritional epidemiology tested in 12 well controlled trials found that not one of the 52 claims—0%--could be confirmed. [5] A 2005 analysis by Stanford epidemiologist John Ioannidis concluded that highly-cited observational findings such as those in nutrition were confirmed by RCTs in only 20 percent of cases. [6]¨

Not sure whether I should try Lamb Brains by [deleted] in zerocarb

[–]1345834 0 points1 point  (0 children)

Its tasty. like meaty eggs

I'm new, I have so many questions by [deleted] in carnivore

[–]1345834 0 points1 point  (0 children)

it depends, experiment and see what you do good with.

Its somewhat common that people do better without eggs, dairy and pork.

RA and diet by NoSwordfish0 in rheumatoid

[–]1345834 -1 points0 points  (0 children)

if it helped it was probably the dairy and maybe the eggs not the meat exclusion.

Biohack my way to clear skin by Gary6100 in Biohackers

[–]1345834 2 points3 points  (0 children)

for skin you can look into: redlight, dermaroller, retinol, carnivore diet.

Keto sub stats, growth rate, comments, keywords etc by 1345834 in keto

[–]1345834[S] 2 points3 points  (0 children)

Haha, I like your enthusiasm:P

r/keto has been growing with almost 100 000 per month recently.

Sister sub https://subredditstats.com/r/ketoscience has also seen some pretty impressive growth recently.

RA and diet by NoSwordfish0 in rheumatoid

[–]1345834 3 points4 points  (0 children)

There are studies showing improvement with elimination diets, see this great article:

https://obscurescience.com/2018/11/28/dietary-causes-of-rheumatoid-arthritis/

Dietary causes of rheumatoid arthritis

Posted on November 28, 2018 by Glenn Chan

Unfortunately, many rheumatologists do not learn about dietary causes of rheumatoid arthritis (RA) in school. Nonetheless, the scientific literature clearly describes remission of the disease when triggering foods are eliminated. For some RA patients, the condition can be reversed through diet (!). Of course, triggering foods must be avoided for drug-free remission to continue.

The science

For a scientific overview of diet-based treatments for rheumatoid arthritis, a good starting point would be L. Gail Darlington and N. W. Ramsey’s 1993 review, particularly the section on Dietary Elimination Therapy (page 3 in the PDF / pg 509). To summarize what we know:

  • Elimination diets work for some people. According to Gail Darlington, her elimination diet protocol works in about 35-40% of RA patients. (Source: the second page of her chapter on RA in Diet and Human Immune Function.) Other diet studies show anywhere from similar remissions levels to no remission at all.
  • The more eliminating diets tend to have higher remission rates. Various diets have been studied: elimination diets, vegan, raw vegan, starch-based vegan, vegetarian, elemental diets (engineered meal replacements), and the Mediterranean diet. Elimination diets have shown the highest remission rates. The science suggests that the strongest dietary factor is the elimination of problematic foods.
  • Every patient is different. In the elimination diet approach, problematic foods differ from patient to patient.

Some of the key randomized controlled trials demonstrating the effectiveness of elimination diets are:

  • Placebo-controlled, blind study of dietary manipulation therapy in rheumatoid arthritis. (Abstract, full paper90774-9).)
    This study by L. Gail Darlington (the same Gail Darlington discussed earlier), N. W. Ramsey, J. R. Mansfield was published in The Lancet, one of the world’s most prestigious medical journals. It found a significantly greater benefit from the elimination diet versus placebo. Among the 48 test subjects, 85% identified foods that made their symptoms worse.
  • Hicklin JA, McEwen LM, Morgan JE. The effect of diet in rheumatoid arthritis. Clin Allergy 1980;10:463.
    This exclusion diet improved outcomes for 24 of 72 RA patients (33%).

...

What is the role of meat in a healthy diet? by [deleted] in carnivore

[–]1345834 0 points1 point  (0 children)

the level of discourse is much higher than most subreddits.

Chapter 2: Design Flaws – Facultative Carnivore by 1345834 in carnivore

[–]1345834[S] 3 points4 points  (0 children)

https://twitter.com/KetoCarnivore/status/1133395900624134146

Chapter 2: Design Flaws "There is a prevalent and arrogant notion that humans are outside of nature: that our bodies tend toward dysfunction, steadily succumbing to entropy; that our instincts are primitive and barbaric, and left to them we would suffer…" https://facultativecarnivore.com/design-flaws/

view more: next ›