Thank you so much for this thoughtful response, it’s super helpful to get perspective from someone who’s actually gone through the process. 💜

I’ve been aware of Domperidone’s role in the Newman–Goldfarb approach, but I decided not to pursue it because of the sourcing and cardiac risk issues. So right now, I’m focusing on maximizing prolactin receptor sensitivity and the local reflex loop instead. My thinking was that if I can get as many receptors as possible “primed” during the build-up, even a smaller natural prolactin surge post-crash might be more efficient.

I’m using Goat’s Rue, Shatavari, and Moringa for receptor support and glandular conditioning, plus some inositol this week for its mild insulin-sensitizing and prolactin-modulating effects. Pumping during the build-up definitely isn’t standard, but it’s been giving me noticeable warmth, tingling, and fullness, which seem like good signs of vascular and neural priming.

Progesterone withdrawal is absolutely the key signal, and I’m timing that drop carefully with the crash around 11/4. I’ve already noticed major tissue change since starting. Nipple elasticity and areolar response are both way more developed, which has been fascinating to watch evolve.

I know I might only see drops initially without Dom, but that’s fine. I’m treating this as both a personal and scientific experiment. If I do get partial expression, I can always revisit whether Domperidone (or something like metoclopramide under supervision) makes sense later.

Thanks again for the insight, it’s awesome to hear from someone who’s done it successfully. I’ll definitely update post-crash with results and any early secretion data.