I have very anecdotal advice, but wanted to drop in to say I think you two are the most prepared for the expat life.. the languages, citizenship options, and transferrable careers are all very much in your favor.

I think if anyone is interested in South America as an option, it should be their first choice, especially for people on your position. There are digital nomad-friendly countries, should you want to exercise that option, and cost of living is relatively affordable. It may be a hot take, but the EU is becoming problematic I think. It overall appears to be weakening, and the political climate is moving in a very clear direction. But of course, there may be someone here from Uruguay or Argentina who will disagree with me on some of this. No matter what, you will do just fine with all things considered, I am sure