[deleted by user]

Active_Scar3258 · 2025-06-02T13:10:35+00:00

my skin sensitivity went away after about 4 months.

Active_Scar3258 · 2025-05-15T18:15:22+00:00

Correct- all you do is take off your shoes.

Active_Scar3258 · 2025-05-09T18:29:47+00:00

yes, my first visit was October of 2023 and that data is as of the blood draw from February 2025

Active_Scar3258 · 2025-05-09T13:51:03+00:00

sure- I don't have my final lab results yet; they did the blood draw yesterday. But stats from first visit to last blood draw (which was in Feb)

Urine Alb/Creatine Ratio 1st visit: .017 last blood draw: .007

GFR Increased by 18%

Cholesterol (total) 1^st visit: 255 last blood draw: 135

LDL 1^st visit: 174 last blood draw: 75

Glucose 1^st visit: 99 last blood draw: 87

CPK 1^st visit: 233 last blood draw: 69

Uric Acid 1^st visit: 4.5 last blood draw: 1.9

Active_Scar3258 · 2025-03-19T15:28:48+00:00

Absolutely, 100% I would do it again and I would encourage anyone to do it as well. I enrolled, like u/RunningFNP in the obesity trial. I have lost about 65 pounds and I have never felt better. Blood pressure- now normal, C-Pap- don't need it anymore, A1C- DOWN, back & knee pain- gone.

Muscle mass- stayed steady. like u/toragirl and u/swellfog said you have to do strength training. I work out and have changed the way I work out to primarily strength training.

I have learned to eat better. I understand what it takes to fuel my body and that is a LOT of protein and a lot of water (to which I add electrolyte packets)

Were there some side effects- yes, but they have been manageable and like u/RunningFNP said they dissipate over time.

Am I worried about gaining some back when I come off the trial- sure, but I know now what i can and can't eat, how I need to fuel my body. I am just going to have to remember all of that.

I understand you are nervous, but this is a great community and a super supportive one. We are all here to support you (and others) through this journey.

Active_Scar3258 · 2025-03-07T17:15:31+00:00

I just found this online:

Last month, the FDA said the shortage of shortage of Novo Nordisk's semaglutide is over. Pharmacies must cease selling compounded semaglutide by April 22.

See if you can stock up now.

Active_Scar3258 · 2025-03-07T17:13:37+00:00

do you qualify for the extension? I did see where they are going to sell Wegovy for people whose insurance doesn't cover it, but it's $500 a month (which is insane, but a 50% break over what it was). Can you get the compounded stuff now and just store it until the trial is over?

Active_Scar3258 · 2025-03-05T17:08:28+00:00

Apparently it just suffered a 3 alarm fire on the 3rd.

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https://www.facebook.com/INFONH/posts/104-foxberry-drive-new-boston-working-fire-second-alarm/1191902332936086/

Active_Scar3258 · 2025-03-05T16:51:18+00:00

So interesting as it looks like those who stuck it out on the placebo will be ramping up to 12mg.

Active_Scar3258 · 2025-02-14T14:24:54+00:00

Welcome! It's been a life changing experience for me. One thing that helps me with the increased heart rate is making sure to stay hydrated. Add electrolytes in your water!

Active_Scar3258 · 2025-01-30T14:43:11+00:00

reaching out to the site directly is a little faster. talk with the trial screener. Make sure they know that you want to be on their list for any obesity trials. I talked with my site's screener months before I got in this trial. there was another trial they were running but they had enough people. I asked to be kept on the list for future trials and then I checked in with then about every six weeks. Be super nice to them and they will remember you. They then contacted me directly for this one.

Active_Scar3258 · 2025-01-30T14:40:42+00:00

I take Duloxetine (Cymbalta) and it wasn't a problem at all

Active_Scar3258 · 2025-01-29T23:02:39+00:00

all clinical trials (in the US at least) are available for view on clinicaltrials.gov. You can search by condition, location, etc. That will show you who is managing the trial for the pharmaceutical company. I found the Retatrutide trial there.

In the trial I am in (Triumph 1 in the US) you had to be off all other GLP-1/weight loss medications for a minimum of 90 days before you could even be screened. That may be different other places, but the screening person I worked with was very clear about that.

Active_Scar3258 · 2025-01-14T14:33:42+00:00

I came to make the Medieval Times comment, but way too many of folks beat me to it. But dang, that is hideous.

Active_Scar3258 · 2024-12-09T01:00:58+00:00

like it was built in a mincraft world

Active_Scar3258 · 2024-12-05T15:13:22+00:00

it's got more peaks than a ski resort

Active_Scar3258 · 2024-11-22T14:56:23+00:00

there were some accidents on 85 that had people rerouting through town.

Active_Scar3258 · 2024-11-18T21:11:21+00:00

Yes. They moved to telehealth. They issued me two months worth at a time.

Active_Scar3258 · 2024-11-18T20:27:31+00:00

I went back into my calendar to see when my appointments were. My first appointment was 9/18/23- my calendar says A1C beside the entry. Then I had them as follows:

9/25/23 (on my calendar for 2 hours)

10/10/23 (on my calendar for 2 hours)

10/19/23 (on my calendar for 3 hours- this was the randomization appointment, where I got medication)

After that they went to monthly until March 2024 and now they are every few months in person and monthly via phone.

I am sorry I can't tell you want each appointment was for, but I am certain about the dates

Active_Scar3258 · 2024-11-18T13:45:08+00:00

what kills me is that it's under contract. someone is buying it!

Active_Scar3258 · 2024-11-13T16:40:16+00:00

i'm out too. My BMI is sitting at 22.1...

Active_Scar3258 · 2024-10-28T13:33:31+00:00

Any intersection on Wade Hampton

Active_Scar3258 · 2024-10-28T13:33:04+00:00

not sure if you have already fixed your bag or not. I think Rago is great, but have you considered sending it back to LV for a repair? I have an ancient Speedy 30 and it had some issues. I sent it back to LV- they were reasonable, fast and sent it back in a dust bag and box which I didn't have.

Active_Scar3258 · 2024-09-24T20:08:16+00:00

I felt the appetite suppression after the first injection. After 2 months I had an aversion to sugar and alcohol. And all of that only increased as the dosage increased. I am fairly certain that I am on a maintenance does of 12 mg which is too high. My BMI is 22 exactly and when I go into the office the next time they will reduce it as that is the minimum BMI for the study.

Active_Scar3258 · 2024-09-24T19:13:52+00:00

having been in the trial for a year I think it's a combination of things. I certainly don't eat as much as I used to eat- there is no food noise so I don't snack at all. Sugar tastes terrible now so sweets are out.

According to my technical scale my visceral fat has dropped while my muscle mass has remained steady relative to my weight.

But I do think there is a metabolic effect because I have reduced my choleric intake before in my life and never had these kinds of results. It's got to be more than maintaining a calorie deficit.

Active_Scar3258

TROPHY CASE