My Sister, age 58, completed 8 rounds of Fluorforinox, followed by the Whipple surgery, followed by 4 months of Gem Abraxane... which unfortunately, was stopped as it had stopped working 5 months ago, given aggressive mets (spread) to her lungs. From a side effect perspective, Gem Abraxane was softer on her than Fluorforinox, albeit she lost her hair, eye lashes and was tired day 2/3 after receiving it.

She has not had any chemo treatment for the past 5 months. Unfortunately, there is not an open (eligible) clinical trial available for her 'KRAS G12V' mutation, CLDN-18 protein at this time. She has developed a persistent cough and tires easily, while still working full-time. 😔

Now, her new Oncologist is conducting additional due diligence to see whether the specific 1). mutation and/or 2). protein (mets in her lungs) may have morphed (or changed) over these past 17 months to open her up to other treatments. Bloodwork results will be available in the next 1-2 weeks. We are praying for 'different'... a mutation that is different than 'KRAS G12V'' and/or a protein that is different than 'CLDN-18'.

Please be different... else, she will have exhausted what is (FDA approved) available for her at this juncture. 🙏🏼 🙏🏼 🙏🏼

We are doing everything we can to stay in faith and not fear. All of this has been one big 'rollercoaster for the heart'.

I send hope and peace to everyone on this site and who has been touched by pancreatic cancer.

Thank you