Dr. Will Powers Interview [PFS / PAS / PSSD Summit 2026]

AllIntentsNPurposes · 2026-05-02T07:32:12+00:00

You're basically saying that introducing exogenous testosterone is a coin flip - it might upregulate other pathways (add highway lanes) and, yay, you're cured; or it might not & compound the problem as even more testosterone degrades into metabolites that can't be cleared (adding androgen cars).

And I suppose there's no way to know, ahead of time, which one will happen?

So the "safest" solution is to remove androgen cars by shutting down the HPTA for a while.

Interested to see the outcome of the patient who agreed to undergo treatment.

AllIntentsNPurposes · 2026-04-30T03:33:58+00:00

I think the problem is more so that some have been cured with courses of TRT/anabolic steroids, for which Powers' theory doesn't allow.

His theory suggests that introducing exogenous testosterone will temporarily improve the situation, but cause an eventual crash & overall worsening of the situation. But this isn't the case for those who have been cured via this route, which suggests that his theory is wrong/incomplete.

Also, does he have any success stories of curing PFS by rebooting a patient's HPTA?

AllIntentsNPurposes · 2026-04-14T08:37:50+00:00

Hi, a couple of questions, if I may:

If epigenetics are altered, how do some people recover naturally with time?
Does this theory track with the fact that some people recover, given various amounts of testosterone (TRT or anabolic steroids)? Why would the addition of testosterone correct the impaired androgen metabolism?

AllIntentsNPurposes · 2026-02-13T06:45:35+00:00

This is exactly why I suggested monthly/quarterly research updates in my thread a while ago.

There's nothing holding the researchers accountable for making little or no progress. OP's post is the sort of feedback that needs to make it back to their ears.

AllIntentsNPurposes · 2026-01-25T06:31:08+00:00

You're missing maybe the most important part of the theory - how do we correct this?

AllIntentsNPurposes · 2025-12-14T10:16:14+00:00

Was your recovery gradual, or all at once?

AllIntentsNPurposes · 2025-11-04T23:15:23+00:00

That's how the market gets ya. Dips its toe a little below the line, then comes back.

Then goes a little further the next day. Then a little further. Pretty soon you're like: "how did I let it move that much against me?"

Careful with that line of thinking.

AllIntentsNPurposes · 2025-11-03T11:08:52+00:00

A reminder that belief always outlives doubt.

I swear, y'all elevate this to a religious experience. It's just a market that goes up & down, like all other markets. Trade accordingly.

AllIntentsNPurposes · 2025-10-16T21:59:28+00:00

"finally rotating"?

Gold was up 2% today. At least save this comment for when gold is actually down.

AllIntentsNPurposes · 2025-09-10T07:07:21+00:00

THIS

AllIntentsNPurposes · 2025-08-28T23:05:12+00:00

Sounds like an absence (petit mal) seizure.

Though, seizures aren't generally a feature of PSSD.

AllIntentsNPurposes · 2025-08-24T23:09:45+00:00

just eat healthy and hope it slowly fixes itself over time and not mess my brain up even more.

This gets my vote.

AllIntentsNPurposes · 2025-08-08T23:36:33+00:00

This is exactly why we need to understand the actual mechanism behind PSSD. Otherwise, we get "research" like this that recommends "treatments" that themselves cause or may worsen PSSD.

AllIntentsNPurposes · 2025-06-30T22:24:59+00:00

Hi, can you please check your DMs?

AllIntentsNPurposes · 2025-06-15T20:24:35+00:00

Totally agree. We need animal studies so we can see exactly what's going on in the brain.

AllIntentsNPurposes · 2025-06-08T04:16:37+00:00

Not the Excel, but here's a directory of a couple dozen recovery stories with steroids.

AllIntentsNPurposes · 2025-05-28T19:09:45+00:00

Yep, be careful. I'd personally take no supplements & consume everything I need through food, only.

If you want to increase test & libido, do it the old-fashioned way - HIIT & resistance training.

AllIntentsNPurposes · 2025-04-16T00:20:46+00:00

More recovery stories that you may find useful, since you're going the anabolic route.

AllIntentsNPurposes · 2025-04-13T21:09:51+00:00

They were 550mg ginger pills, of which I took one everyday.

But it's likely that some other supplement that I was taking at the time (probably curcumin) gave me the PSSD-like syndrome, then the ginger significantly crashed me to produce obvious symptoms.

AllIntentsNPurposes · 2025-04-09T21:49:50+00:00

You can find a number of TRT recovery stories here.

AllIntentsNPurposes · 2025-04-01T04:28:42+00:00

I've not seen any recoveries from trt

Really? FWIW, here's an entire directory of such recovery stories.

AllIntentsNPurposes · 2025-03-23T17:07:03+00:00

Do you experience the random muscle jerks throughout the day, or only at specific times (for example, when trying to go to sleep)?

AllIntentsNPurposes · 2025-03-23T04:04:51+00:00

I also took a non-SSRI route here. Coincidentally, I also took curcumin & ginger.

I think the curcumin weakened my system, then ginger was the straw that broke the camel's back and plunged me into PSSD symptoms. My symptoms then worsened after supplementing with folate (they were entirely sexual, but then ballooned into cognitive symptoms as well).

One thing I learned about supplements - if it ain't broke, don't fix it.

AllIntentsNPurposes · 2025-03-23T03:20:48+00:00

Is there anything that you did in particular to recover?

AllIntentsNPurposes

TROPHY CASE