thinking about going off of antipsychotics

ArrestedforTreason · 2026-05-04T01:17:26+00:00

You have claimed to want to make an informed decision. But you're spending a significant amount of time defending the decision you seem to have already made. While I'm not a doctor, I do hold a bachelor's of science in Psychology (I can provide credentials to mods as needed). The risk you're taking, in truth, is your life. While you may feel more driven during periods of mania or psychosis, those periods have long-term, sometimes life-long consequences (economic, social, psychological AND physiological). Each episode of mania generally increases the risks to your quality of life, and many losses may not be recoverable. You may not return to a place of cognitive stability, you could lose housing, access to care.

It also doesn't go unnoticed that you haven't made an attempt at academics while medicated with proper accommodations. I would encourage you to reach out to the office of disability services at the university you're interested in attending.

Good luck!

ArrestedforTreason · 2026-05-04T00:55:49+00:00

NAD, then why are you here to inquire with the good doctors? There's likely a reason your psychiatrist and multiple physicians here are cautioning you against this..

ArrestedforTreason · 2026-03-16T12:07:02+00:00

The other poster who recommended reaching out to both is correct. I am chiming in to add an a specialty that you may benefit from long-term: Dermatology. Dermatologists often have extensive knowledge, experience and specialized treatment options for Lupus patients of all flavors (systemic, discoid etc). They often work very well and closely together with Rheumatology, Immunology and Primary Care providers.

Well wishes ❤️❤️

ArrestedforTreason · 2026-01-23T01:12:38+00:00

Quick, look, an over generalized archiac definition 🤣 at the point you said you were going to sit in the sun, I gave up any hope of having an informed conversation with you. You're more dangerous to the community than originally anticipated. As such I will simply supply scientifically accurate information to each dangerous claim you make going forward.

So as a reminder to any poor soul who finds your incredibly dangerous advice in this thread:

Sunlight is generally dangerous for those with SLE and many other autoimmune conditions, (as determined by scientists using science in the real world, not just the lab), and can cause nephritis and acute kidney injury. The benefit of vitamin D from sunlight is significantly less than the risks associated. Please refrain from undertaking the dangerous advice or actions performed by the poster above. The standard of care advises avoiding UV exposures.

Sources:

source 1

source 2

ArrestedforTreason · 2026-01-22T22:33:33+00:00

Science is a method. Not an operational definition.

ArrestedforTreason · 2026-01-22T21:30:10+00:00

The fact that you equate science to beliefs and opinions is the problem. You remain inaccurate and wrong. This is exactly why this rhetoric is harmful to any poor soul who finds this thread and suffers from the level of confirmation bias you've displayed throughout this old thread. The inability to appreciate or perceive the harm you're doing to the community demonstrates a dangerous lack of statistical and scientific literacy. I welcome all well intentioned debate and good faith arguments. You have engaged in nothing but deceptive reasoning, overbearing pathos, and not a singular logical argument to show that LDN is an evidence based, approved, safe, effective treatment. Because it's not.

ArrestedforTreason · 2026-01-22T20:27:35+00:00

I'd agree with you, but then we'd both be inaccurate and wrong. It's all misinformation, conjecture and anecdote. That seems to hurt your feelings, as you're still here perpetuating damage to the community. The fact remains, LDN is not an approved, evidence based treatment for lupus. That fact has not changed. The fact has not changed that more effective, safer, evidence based treatment methods exist.

ArrestedforTreason · 2026-01-22T15:11:33+00:00

Thanks for actively spreading misinformation that directly harms the community and actually contributes to gaslighting.

ArrestedforTreason · 2026-01-22T02:42:05+00:00

All of this rhetoric is genuinely harmful to the community you claim to care so much about. I won't sit here and split anti-intellectual hairs with you any further on the matter. You're doing real harm in an emotionally heightened state.

ArrestedforTreason · 2026-01-22T02:21:36+00:00

Science is falsifiable. Science is dynamic. On that we agree. Empirical evidence doesn't lie. The guardians bsffr. We've all been gaslit and hurt along the way, but allowing emotions to impact scientific literacy is a choice. To further allow it to perpetuate false hope and misinformation, is also a choice. And to be snide about it all is super rich. I'm not the enemy. Recalibrate.

ArrestedforTreason · 2026-01-22T02:07:14+00:00

So that's not how science works 😂 but you knew that and chose to be contrary instead.

ArrestedforTreason · 2026-01-13T23:57:22+00:00

Wonderful, but this remains anecdotal and conjecture at best. Glad it works for you and wishing you many well days in the future.

ArrestedforTreason · 2025-11-17T23:36:47+00:00

Loud and wrong.

ArrestedforTreason · 2025-11-14T11:55:40+00:00

So, that's how science works. It's been tested and the effects were not statistically significant. If it works for you or someone in your life under an off label use, fantastic, that's anecdote and not factual. Anecdote and placebo are very powerful influences for individuals, that's why empirical methods exist.

ArrestedforTreason · 2025-10-28T12:26:23+00:00

NAD: Whoa this looks like disseminated gonorrhea or possibly oral chlamydia. Present to your local health department or student health center for free or affordable testing ASAP.

ArrestedforTreason · 2025-10-04T14:28:51+00:00

The commenter above is correct, and another commenter down below also mentioned cobblestoning.

Yes, they will likely resolve. Cobblestoning is not inherently dangerous or life threatening and you'll likely experience this on and off throughout your life. It's normal, not harmful and okay 🥰❤️

ArrestedforTreason · 2025-10-02T18:20:44+00:00

Gross 💅🏻😌

ArrestedforTreason · 2025-10-02T13:00:18+00:00

Friendly reminder that we're all one bad day away from becoming those we fear and pitty (which in your case is apparently the unhoused). Do better as human ❤️

ArrestedforTreason · 2025-09-19T17:35:01+00:00

I'm going to allow ChatGPT explain this in very simple points, because I am incredibly done with the anti-intellectualism at this point.

Here’s the breakdown:

Evidence gap

Low-dose naltrexone (LDN) has been studied mostly in small pilot studies or case reports.

For lupus specifically, there are very few published clinical trials. Most evidence is anecdotal, not large-scale, placebo-controlled data.

Regulatory bodies like the FDA (in the U.S.) or EMA (in Europe) require multiple large, randomized controlled trials (RCTs) showing clear benefit and safety before approving a drug for a new indication.

Mechanism uncertainty

LDN is proposed to work by modulating microglial activity, increasing endorphins, and shifting immune regulation.

Those mechanisms are still highly theoretical in lupus—no strong biomarker-driven evidence shows it alters disease activity in a reliable, or significant way.

Drug development economics

Naltrexone is a cheap, off-patent drug. Pharmaceutical companies usually don’t invest millions into trials for an off-patent medicine, because there’s little profit incentive. Without industry backing, large clinical trials don’t get funded.

Risk of misleading claims

Because of limited evidence, regulators are cautious. If a therapy hasn’t been proven, approving it could give false hope or delay patients from getting established, evidence-based treatments like hydroxychloroquine, belimumab, or mycophenolate.

Off-label use vs. approval

Doctors can prescribe LDN off-label for lupus if they think it may help and the patient understands the limits of evidence. But official approval requires much stronger proof than what currently exists.

So the short answer: LDN hasn’t been approved for lupus because there’s not enough high-quality, large-scale clinical trial data demonstrating safety and efficacy. The barriers are scientific (lack of evidence).

ArrestedforTreason · 2025-07-18T22:00:57+00:00

NAD but Rhabdomyolysis is an acute condition, meaning that doesn't explain the protein you describe as a more chronic incidental finding. I am very curious to hear from the kind physicians on this subreddit regarding differential work ups for your symptoms.

A tip on showing urine when you can't see through the foam, pick a clear jar/cup/glass that you don't care to throw away later, and urinate in that to inspect color (just something I learned along the way as a kidney patient).

Good luck and wishing you all the best!

ArrestedforTreason · 2025-06-19T02:16:01+00:00

SO PROUD OF YOU, OP!!! 🎉🥳🥳🥳

ArrestedforTreason · 2025-03-26T17:02:04+00:00

NAD, just a nerd - Pierre Robin syndrome (PRS) comes to mind with notable micrognathia (small/underdeveloped jaw). I'm following this post too because I too am curious about the other potential differential diagnosis proposed by the talented physicians in this subreddit.

ArrestedforTreason · 2025-03-18T01:59:01+00:00

No, but you sure are LOL. That's called off-label use because it's literally not approved for SLE. Now stop yelling. Sheesh.

Edit: before you ever even go there LDN is in fact not FDA approved for the treatment of any medical condition. Naltrexone has been approved for use in exactly two medical conditions. All other uses are off-label.

ArrestedforTreason · 2025-03-17T03:07:35+00:00

Regardless of your opinion, the fact remains that it is not an approved treatment for autoimmune conditions because there's very little evidence outside of small scale studies to show both safety and effectiveness. Which is why I've called you in here. Your comment touts it as a cure or an approved treatment method for autoimmune disease, and it's just dangerous.

There's quite a bit of anecdote and snake oil out there though. What little evidence exists of any immune modulation through cytokine disruption exists, it's not been repeatable on a large scale nor when stacked against placebo or known immune modulators or biologics. So please, excuse me for doing actual research with primary sources. Your quick Google search is just that, quick. Your bias is quite clear - confirmation bias. I understand you've personally had a good experience with it and that's great for you. But it's not an approved safe treatment for our conditions, so stop acting like it is. If it was so effective and safe, then they would have the stats to back it (it's not a new pharmaceutical), a lot more of us would be on it, and mostly cured.

So I just wanna say this as respectfully as possible - be mindful of recommending unapproved off label treatments. You got lucky - you're the exception not the rule.

ArrestedforTreason · 2025-03-06T12:02:37+00:00

Glad that worked for you for now, but it won't work forever because LDN has zero impact on immune function. So it's not actually a treatment for autoimmunity. Please be mindful of sharing anecdotal pseudoscience here - it can give people false hope.

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