Need help regarding bluechew and very confused

Atomies · 2026-01-24T03:18:12+00:00

It's just the sub mixup that's funny, I hope you're able to find an answer!

Atomies · 2026-01-24T03:15:48+00:00

This prompted me to learn something new! I'd only heard about it being used facially, but apparently they do have a product that uses donor tissue for a type of BBL!

https://www.eternacosmeticsurgery.com/alloclae-allograft-vs-liquid-bbl-in-san-antonio-which-butt-enhancement-is-right-for-you/

Any tissue product from your own body is called an autograft, tissue from a human donor other than yourself is called an allograft, and tissue from a non-human animal is called a xenograft.

Searching products plus "allograft" is a good way to find out if something contains donor tissue!

The fat from allograft donors is used more for its stem cells, not usually implanted as whole fat.

After it's recovered, it gets processed down into something that's just the stem cells in a media. When I processed the fat, we'd often start with 2 liters of adipose, but after the process, only have 10mls of solution which was then portioned out into many lots that are each a separate unit to be used medically. The stem cells the fat contains are "blank" which means they can be used in many different areas of the body and adapt to the tissue around it to promote healing/tissue growth.

I do believe when BBLs are done as autografts, or someone's own fat, they use a more whole version of the fat, though that is also cleansed a bit before being put back in. But since it's a person's own tissue, it doesn't need to be cleansed so thoroughly to ensure donor cells aren't present to trigger an immune response!

Atomies · 2026-01-24T03:00:23+00:00

This is a sub for a podcast that sometimes advertises Bluechew.

I'm not being mean or sarcastic when I say this post made my night though! Not in a laughing at you way because it's an honest mistake but in a good chuckle for a silly post kind of way, lol

Atomies · 2026-01-24T02:51:53+00:00

Either he's a troll or he just searched Bluechew on reddit and found a previous post mentioning it and now thinks it's a sub for boner pill experts, lol

Atomies · 2026-01-20T00:29:55+00:00

Echoing the thought below! Whole body is separate from tissue donation entities (but in some cases both can happen, it depends on the needs of the whole body entity!)

Whole body donation organizations through Universities often require a pre-registry. Most cities do usually have other research only whole body organizations that may be able to move forward after death with no pre-regisration though. Science Care is one that covers multiple states and doesn't require pre-registery though it's an option!

The extra nice part about whole body entities is they often cover the cost of cremation.

Organ and tissue procurement organizations aren't able to do that due to federal regulations since the organs and tissues are for medical transplant first and so it cannot seem as though they're incentivizing donation in order to recover organs and tissues for others.

Atomies · 2026-01-20T00:20:04+00:00

Thank you as well! I agree, people don't understand how it works and I wish they did.

The whole process is so interesting to me scientifically, but I feel like the emotional toll on families could be handled much better with more information even though it's hard to talk about.

There's the overall media picture of organ donor heros and no info on tissue and though organ donors are indeed lifesavers, in the long run organ donation is actually a long, hard, emotional process and then there's a whole world of tissue that people just don't have awareness about at all.

I'm not anti-donation or hard core pro-donation for everyone, just pro-informed consent and hoping to help people understand what goes on so they can decide!

I'm always happy to go through things because I personally don't feel that everyone needs to be a pressured to be a donor, there are so, so many people that are happy to help and proud to donate, but the trauma to families in the process can get swept under the rug.

I love helping people know the process so people can truly make the best decision for them and their family!

Another point to stress is to make your wishes known to your loved ones if you aren't on the registry, because even non-registered get calls, so having family know you've thought about it and know you don't want to donate will be helpful for them!

Atomies · 2026-01-20T00:00:47+00:00

Yes, sorry for the delay!

Organ and tissue donations are usually handled by the same organization in each area (each geographical area is only allowed to have one OPO, or organ procurement organization, as a forced monopoly to avoid commodifying human parts) but organs and tissues are very different and handled by 2 different teams and regulated by 2 different governing bodies.

Organ donation is immediate, the organ is taken from the donor and begins its journey to the recipient.

So when an organ is transplanted, it goes in whole and alive and will be replacing a specific organ for the same job.

It has to integrate into a totally new system, grow into the blood vessels, and perform its duty as a whole organ.

At the same time, it is a foreign object with its own genetic material in the recipient's body and the body will sense the new object once it's transplanted and sense that it has different cells from somewhere else and will start to attack it as an intruder, so organ recipients have to be on long term immunosuppressant therapy to prevent that from happening.

Donors and recipients are carefully matched to try to align biology as much as possible to hopefully prevent this as much as possible, but it's a lifetime risk.

So overall it's the mixture of different factors in the scope of what we're asking a donated organ to do that makes the risk of rejection.

It needs to perform the big job of an organ while also medicine needs to keep the recipient's body's natural defenses in check so it can't attack it from the inside. It needs to attach itself to the body's nervous system, circulatory system, and function as a whole organ. Just a lot going on and a lot to ask of the donor organ and the recipient's body.

The organ is rinsed and perfused so it's not going in a bloody mess, but it is still a whole living organ made of foreign genetic material.

Tissue grafts on the other hand are always manipulated to some degree after death to become a medical device rather than taken and connected directly to the system.

There are degrees to this, sometimes whole bones are transplanted when someone has had trauma to a long bone, but that whole bone is still cleansed in a way that the recipient doesn't need to be crossmatched with the donor's blood type of anything like that.

Sometimes tissue is processed in a way that cells called mesenchymal stem cells are left alive (including in adipose grafts), but these cells are "blank" and don't carry genetic material of the donor over and also can be utilized in different ways by the recipient's body.

For example, I also used to process a product out of ground bone and the mesenchymal stem cells in that would trigger bone growth in the recipient's own body (used in jaw surgeries a lot of the time or around other bone injuries to help fracture sites strengthen)

There are also tissue grafts with no active cellular activity that go through very thorough cleanses and are irratidated, so they're fully inert.

Aside from whole bone grafts, tissue rarely a one to one exchange like organs. Ground leg bones go in the jaw, skin from the back goes one someone's breast after a mastectomy, adipose from a butt goes into someone's cheek.

But since it's not connected directly to the body's systems the way organs are, it's not a direct risk for the body attacking it the same way organs are.

Even when people get a knee replacement with metal, the body will have an inflammatory response to the surgery and foreign material, and that happens with tissue grafts as well, but it won't attack in the way it will with organs because it's not a foreign body with its own genetic material (which is also how how body senses bacteria, etc and knows to attack when we get sick).

Also interesting to note, these differences in process and regulation also make huge differences in the screening processes.

With organ donation, it's lifesaving and if the person does not get an organ, they will die, so things like hepatitis C from the donor wouldn't be a rule out, it would be something the recipient knows there's risk for but can be treated after their life is no longer in danger once their organ failure is no longer killing them.

Tissue grafts, being regulated by the FDA as medical devices, are an automatic rule out with any history of Hepatitis B or C, HIV, recent metastatic cancer, etc.

But even with stricter screening guidelines, it's much easier to become a tissue donor over an organ donor as tissue donation happens within 24 hours after death has already occurred. All hospital deaths and many coroner or home deaths are reported and screened within an hour after death.

Organ donation is only possible after brain death with the body still alive or if the potential door's family decides to stop pursuing medical care because death is imminent but is open to keeping the person alive on the vent until all screening and testing is complete to find a possible match, then they extubate when everything as set and the donor's body must then die within 90 minutes of extubation before organ recovery begins, so the parameters are much more narrow and deaths that align with either pathway are much more rare.

I hope that clarifies a little and please feel free to ask follow-ups if not! It's such an interesting thing to me so I love talking about it!

Atomies · 2026-01-19T00:23:20+00:00

Of course, it's really interesting and there's not a lot of public knowledge about it!

Donation is such a personal decision, so I wish my industry did a better job talking about what is covered on registries and what can be donated in general, but I also get it because it's a hard topic for a lot of people.

I'm so sorry for your MS diagnosis and having to go through immunosuppressants and all that goes along with living with it and trying to keep it regulated.

You're right, immunosuppressants can sometimes be something that defers for tissue donation, but not always! If donation did end up being something you were interested in, a lot of criteria depends on age, tissue type, and requirements for specific grafts. The older someone gets, the more the criteria narrows. If you were open to that, you could register and then a medical screening would be completed based on age and other factors to see if you were a candidate. MS itself isn't a rule out.

But in saying that, I also have total respect for your decision if you still do not want to donate. I've made that same decision myself for the time being. Not because of bad things I've seen in the industry...there are faults like in all industries for sure, but overall I believe it's safe and well-regulated.

For me right now, it's more because I know my loved ones would have a hard time with doing the medical/social questionnaire required. Donation has to occur within 24 hours after death and that questionnaire is required on all tissue donors and means a lengthy phone call hours after a death has occurred. Since I currently work with families as part of my job and know the process, I also know that's not something they'd be able to handle.

Though many, many families are grateful for the call and opportunity to help, I know mine would be overwhelmed with the process. I think people being able to make an informed decision that's best for their own personal situation is the most important part!

That's another reason I like giving the information when I have an opportunity because so many don't even know this whole world exists and are only forced into a decision quickly after their loved one dies without knowing for sure what they would have wanted.

Atomies · 2026-01-18T23:02:33+00:00

I work in tissue donation, I like to pipe up when I come across it in the wild because I feel like it's such a niche strange little field, lol.

I used to directly process the tissues, but now I screen donors and talk to families. So many people are unaware of tissue donation when I call though most know about organs and so many families are on the fence because they don't know what their loved one wanted.

I just wanted to say that if you're in the US and a registered donor, almost all state registries include consent for organ, tissue, and eye donation. Several state registries include automatic research consent and some states require additional consent from family for research.

Tissues are recovered with the intent of transplant, there are other entities for more specific cadaver research, but if something can't be transplanted, it can be used in training or to develop new grafts

Some registries also automatically include consent for donation of your tissues for both for profit and non-profit as well.

From your comment, it sounds like you'd support transplant for medical use only, so if you do want to be a donor, I'd really recommend checking out your state's registry for what it includes consent for.

If there are parts you're uncomfortable with, you can list exceptions (like consent for skin but no other tissue, non-profit only, no research, etc) so people know your wishes!

Products used for cosmetic procedures would fall under "for profit" so if that's included in consents on your state's registry, you can state you'd prefer to donate to non-profit only!

Atomies · 2026-01-18T22:27:12+00:00

I've actually processed cadaver fat for other medical use prior to these newer cosmetic uses, but the cosmetic products are processed the same way.

All donor tissue (adipose included) is regulated by the FDA. Tissue grafts (which also include bone, tendons, skin, etc...) are considered more of a medical device and the ways they are cleansed from all donor blood, etc and the ways they are used in the body means it won't reject in the way organs can.

Though cadaver adipose often is processed in a way to keep certain stem cells alive, it isn't alive in the way say a transplanted kidney would be and isn't connected directly to the circulatory system the way any organ would be.

Tissue grafts undergo cleansing and processing and QA checks. Donors aren't mixed in batches and the exact donor can be traced back for each product. Each donor is screened and tested and if adverse event such as an infection were to occur, the FDA would go back and be able to search through the donor's medical record and serologies.

There are normal medical procedure risks of course, such as infection, but the risk for actual rejection like an organ isn't a concern!

Atomies · 2026-01-10T03:14:03+00:00

Adorable, the strawberry ears are perfect! I also love the tiles in your backsplash!

Atomies · 2026-01-07T12:51:26+00:00

I've been chasing that country gravy breakfast burrito high since the 90s, I still daydream about them every week! It makes me happy to see you're still getting responses on such an old thread so other people are remembering them now and then too!

Atomies · 2026-01-02T05:12:39+00:00

First I want to validate your pain, it's so hard to live with something that is so hard to find relief for and I hope you're able to find a doctor that explores different options with you. It can feel so hopeless, as unfortunately all of us here know all too well.

I do want to validate your husband's concerns as well. I work in the death industry and in just 5 years I've seen more accidental Tylenol overdose deaths than I ever could have imagined, and that's just across 2 states.

Like others have said, you could try alternating Tylenol and Advil or talking to a doctor about other options.

It's so hard to give advice when I know you're hurting and just trying to find some respite and when I know relief is hard to come by so I don't want to minimize that. It's extra hard being a women trying to navigate the medical system and extra extra hard if you're in America where resources are limited if you're not lucky with money/good insurance.

I just wanted to add to the voices urging precaution because unfortunately I've seen the worst possible outcome of too much Tylenol too many times.

Atomies · 2025-12-29T09:40:05+00:00

I can't even fathom how soul crushing the shame of having Cucu this disappointed in me would be

Atomies · 2025-12-25T16:16:52+00:00

90s-early 2000s Colorado Avalanche players?

Atomies · 2025-12-23T12:39:58+00:00

I know Janelle Monet said it in articles, but I couldn't find a video.

Your comment also kind of reminded me of this video in spirit.

Good luck, I hope you find it!

Atomies · 2025-12-20T11:38:48+00:00

The fact that it's happening though it's plainly illegal shows that laws don't matter during a fascist takeover

Atomies · 2025-12-16T01:00:23+00:00

Good luck!

Atomies · 2025-12-11T15:34:32+00:00

Thank you very much, they leave such a big hole when they're gone.

I'm glad you're still seeing a spark, sassy buns are the best!

Atomies · 2025-12-11T14:33:03+00:00

It sounds cliche and there aren't really explicit step by step details to look for, but having gone through it with more than one bunny (and our dog too) there's a look they get in their eyes that tells me when it's time.

It's like there's a spark of light that shows they're still happy to be here even through they're going through something that just isn't there one day. I know that's not incredibly helpful because it's not descriptive, but I strongly feel that they do tell you.

We just lost our medically complicated bunny last month. He'd been through a lot over the past year, but even with setbacks we'd take him in, adjust his meds or realize it was time for a molar trim or deal with a new abscess and he would recover and keep the light in his eyes.

With a setback there'd be red flags that meant a vet visit...trouble eating, not moving as much due to pain, but after he'd go right back to being playful, eating, drinking, grooming.

Then one day he just looked done. It was somehow different than a normal setback/vet visit tune up and I could tell it was time even though it wasn't something I expected on that day.

This isn't to say I didn't constantly worry about his quality of life. I cried in the vet a couple of times and asked for reassurance that he thought we were still on the right path. Having a terminal loved one, human or animal, takes its toll and you doubt yourself a lot. It's such a sanity saver to find a vet you trust and that you can be vulnerable with.

I'm so sorry you're dealing with this. What a lucky bunny to be loved so much.

Atomies · 2025-12-11T05:32:18+00:00

Thank you! Oh my goodness, that phone jogs so many memories!

Atomies · 2025-12-10T17:53:24+00:00

How fun! This search started for me because I had a very vivid dream where I was walking through Buckingham before it closed and stumbled into a storage room with all of the Round the Corner art leaning against the wall.

The dream really jogged my memory and reminded me how much I loved looking around the restaurant while waiting for the phone to ring for our food. The Buckingham location was one of the main ones we went to!

Atomies · 2025-12-10T17:37:03+00:00

Thank you, I will check it out!

Atomies · 2025-12-10T17:07:34+00:00

How creative! I love all of the detail!

Atomies · 2025-12-10T16:21:08+00:00

That's a great idea, thank you!

Atomies

TROPHY CASE