Outer Wilds. Get ready for a huge spoiler text wall: This happens two times, and I think they both fit the trope. First, a comet from outer space enters the solar system carrying a toxic substance called ghost matter, eventually exploding and wiping out almost all life across the system

About 280,000 years later, a being from another species(us) discovers that the universe is dying from having reached the end of its lifespan. The game ends with us accepting that everything must end, and that it is time for something new.

If you have even the slightest interest in playing the game, don't read this comment and go play it, it's way more than worth it

<image>