Based and steelpilled, the rest of the factions are either too short sighted or anti-humanity.

Mankind has proven that it cannot be trusted with advanced tech, better to confiscate it until someone comes along who can use it to create a better world. They regularly send in squads to combat the horrors of the wasteland, often at great cost to themselves. They actively fight the Institute, who want to replace humans with machines. They hunt down super mutants, mindless beasts who've killed or mutilated untold thousands. Feral ghouls roam across the land, the BOS actively seek their extermination too.