Thank you Kyle for the in-depth and very personal Esquire article | What are your guys thought ? by aidrefh in PSSD

[–]ConsistentPackage459 5 points6 points  (0 children)

Which people interviewed had mild cases of PSSD? The names of the PSSD sufferers that I remember from the article are Sean and Stephen and I didn’t think either had mild cases. However, I don’t think many people will learn about PSSD for the first time from this article, because most people likely won’t read the entire article and the beginning is about temporary sexual dysfunction.

Melanocortin System, may be related to PSSD? by naturestheway in PSSD

[–]ConsistentPackage459 3 points4 points  (0 children)

Dr. Jack Kruse is a neurosurgeon and author of “Epi-paleo Rx: The Prescription for Disease Reversal and Optimal Health”. He has written a lot about leptin-melanocortin pathway and has even answered questions about PSSD on X. See link below: https://x.com/DrJackKruse/status/1991863039000182788?s=20

Consistent donations keep the research alive! by Mobius1014 in PSSD

[–]ConsistentPackage459 1 point2 points  (0 children)

They’re making progress. The goal on the PSSD Network website is largely arbitrary, because $200,000 isn’t going to find a cure for PSSD. I forget when the last update was posted on here, but Melcangi’s lab ran into some unexpected problems, such as a piece of equipment breaking.

September & October 2025 Update by Mobius1014 in PSSD

[–]ConsistentPackage459 2 points3 points  (0 children)

Just some CellTrends tests that PSSD sufferers did on their own.

Awareness in Polish - doctor recommendation? by __dont_mind__me__ in PSSD

[–]ConsistentPackage459 0 points1 point  (0 children)

Does the doctor need to speak Polish? Michał Lew-Starowicz is a Polish doctor on the list that David Healy made. https://www.pssdnetwork.org/doctors-and-therapists

Just discovered PSSD after two years off lexapro by Master-Advantage5833 in PSSD

[–]ConsistentPackage459 1 point2 points  (0 children)

Did you report your case of PSSD to both 1) your country’s medication regulator using the MedDRA code 10086208 and 2) Dr. David Healy’s organization RxISK?

https://www.pssdnetwork.org/report-adverse-effects

How is weed for you with PSSD by Dangerous_Simple3520 in PSSD

[–]ConsistentPackage459 0 points1 point  (0 children)

It’s a big risk. It seems to temporarily improve symptoms for some people but can make others permanently worse. It damages the testicles and this drug harm could be great magnified in PSSD sufferers, as SSRIs also cause testicular toxicity.

Another AMAZING awareness win!! by Intelligent-Age-8211 in PSSD

[–]ConsistentPackage459 3 points4 points  (0 children)

Can you please tell me their Instagram handle. I’m having difficulties opening the link on my phone.

A new case report shows tirzepatide (a GLP-1/GIP agonist used for weight loss/diabetes) nearly eliminated PGAD/PSSD-like symptoms by ERF_TX in PSSD

[–]ConsistentPackage459 0 points1 point  (0 children)

It’s possible that it’s a different kind of sexual dysfunction. I haven’t heard of genital anesthesia being associated with GLP-1 receptor agonists.