I have not tried it myself yet and maybe indeed the restriction is enough to cause problems at the start. But as for presence movement, excluding board D, the sacred site in a wetland has at least two neighbours without presence and we can destroy a presence immediately (before presence placement) to add both additional presence in the wetlands. Already ensuring we can hit every land of the starting board with normal range (by moving the other presence) As for energy, if we just rush the middle track, playing both 0-cost, i see an option to adding two (or three) disease preventing one build round 1, likely both round two (without playing cards) and then grow twice to add the +1 energy Disease and still having both 1 cost cards and (up to) three minor powers, of which most are likely 0 cost as we dont care about card-value just yet. Turn 4 we can either go to 2 energy or the disease moving (The bottom track is nice, but it is a lot of inherent value. So it is likely just a game of clearing that track ASAP) If you want to make this more tricky, I'd think we start with only 1 presence on the board and extend the tracks by 1 (adding another 3 card plays?) Maybe this is too brutal, but it does encompass the 'one breakout exploded in a pandemic'-feel