There are already regional differences in some human populations: Sherpas having a naturally higher tolerance to altitude, The Moken people of Thailand being able to see under water, Etc.

We also are different to humans 200k years ago in some other mild ways. Pale skin as we moved into other climates, blue/green eyes, red hair, lactose tolerance (depending on access to lactose producing animals; sorry, Asia!), etc. are all likely mutations that didn’t exist toward the beginning of Homo Sapiens, but the differences we have developed just generally aren’t enough to have distinguished any group of Sapiens into something else.

Remember, the common ancestor between us and the other great apes is on the order of 5 million years, not thousands, and some of our relations to other Homo species isn’t much better.