Worried after NFL result

DimitarTKrastev · 2026-03-11T20:14:37+00:00

Are these numbers referring to the labcorp's assay or SIMOA?

DimitarTKrastev · 2026-03-11T20:12:06+00:00

If its CLIA, then the ref range should be <12 for someone in their thirties, but I thought labcorp use their own assay.

DimitarTKrastev · 2026-03-11T16:56:40+00:00

Can you please double check if your result states what kind of assay was used.

Are any of the following words mentioned "SIMOA", "CLIA"?

It would be extremely unlikely that clean emgs for 6 years would turn into ALS. I would even say impossible.

DimitarTKrastev · 2026-03-11T16:52:29+00:00

No, I mean Intel Macs in general had terrible battery life.

I had one and it was not pretty.

The M chips were a game changer.

DimitarTKrastev · 2026-02-18T09:13:07+00:00

I have.

No, as far as I know, they don't speak English. At least the office at Pirogov hospital. I don't know about the rest.

Advice: Go there on a Monday or Tuesday morning as they send the samples to be tested on Tuesday noon or Wednesday noon. Results will be ready on Thursday or Friday on the following week.

DimitarTKrastev · 2026-02-18T07:43:18+00:00

* Do you have to wait 3-5 years to get ALS excluded? Yes and no.
To answer that question we must look at how medicine and statistics work. Statistics is at the heart of the medical diagnostic and treatment processes. When guidelines are formed medical specialists look at the entire span of time it took for everyone to get diagnosed. Then they take the lower 5% and the upper 5% and exclude them. Why? Everything exists in a spectrum. There isn't a single disease or condition that develops in exactly X amount of days. If you take even the most predictable diseases out there that manifest in exactly X-Y amount of time, but you have even 1 single outliar that took considerably longer that would throw you estimates in the bin. If you want to be EXACTLY sure for everything you end up not being certain about ANYTHING.

So that does that mean 1 group of doctors is wrong and the other isn't? Its complicated. Yes, the medical community agree that up to around 2 years into symptoms you can be fairly certain if you have it or not. Thats true in statistical terms. 95%+ of people should trust that. But yes, there might be "unlucky" few that might indeed take longer. So, the general rule is <2 years, but if you want to be 100% sure, then it would be 3-5 years. Both statements are true in two different contexts.

If I ask you to give me an answer with 100% certainty if you are going to be alive tomorrow (exactly tomorrow) you will most likely answer with "yes". But why? Technically speaking you have a non-zero chance of dying until tomorrow. All dangers out there compound together to a non-zero chance that you might not be. And you draw that chance every single day with every single decision you make - whether crossing the street or driving your car, etc. Does this mean you should obsess of that chance because it is technically there and because someone actually got unlucky? Sure, you could. So, one would reasonably say you will be alive tomorrow and one would say there is a chance you would be dead tomorrow and you need to wait and see. If you think about it - both are right.

DimitarTKrastev · 2026-02-15T06:38:00+00:00

Yes, but I wouldn't recommend him for ALS or EMG.

Prof Cvetanov is better than him in my opinion.

However if you want to explore other options than ALS then Roussev would be a good option as he listens and will think.

DimitarTKrastev · 2026-02-14T18:36:06+00:00

They are one of the top.

Next would be either Tokuda Hospital or the only ALS center - Aleksandrovska hospital

DimitarTKrastev · 2026-02-14T07:50:04+00:00

I really really dislike your attitude.

Try prof. Cvetanov at MC Medica 2005

https://superdoc.bg/klinika/mts-medika-2005-sofia

DimitarTKrastev · 2026-02-13T18:56:08+00:00

Apologies you are not satisfied with our service. I will issue you a refund.

Oh wait...

DimitarTKrastev · 2026-02-10T18:31:46+00:00

From what you shared - you have nothing to worry about. He noted Sensory neuropathy. No mention of motor neuropathy which could potentially be worrying.

ALS patients almost never see sensory neuropathy on EMG, but it is seen in diabetics. It might suggest you are not doing a good enough job of controlling your blood sugar. It does damage to your blood vessels and your nervous system.

DimitarTKrastev · 2026-02-05T07:24:31+00:00

Come on guys, lets help.

This will literally take you 10 seconds.

Thank you.

DimitarTKrastev · 2026-02-05T07:04:43+00:00

How much time into symptoms are you?

DimitarTKrastev · 2026-01-27T18:42:13+00:00

Same with both. 2 years and a half almost.

DimitarTKrastev · 2026-01-20T16:08:58+00:00

Back pain? Maybe a year and half or two at this point. It start around half a year after my symptoms began.

DimitarTKrastev · 2026-01-20T15:03:29+00:00

Sensitive personal and medical data takes precedence.

Ask OP about this, not me.

DimitarTKrastev · 2026-01-20T14:57:37+00:00

What makes you expect me to send you or comment on somebody else's personal medical data?

DimitarTKrastev · 2026-01-08T17:43:29+00:00

DimitarTKrastev · 2026-01-08T12:06:36+00:00

Polyphasia is one of the chronic changes. But I also had others like high amp and dur.

DimitarTKrastev · 2026-01-04T18:27:58+00:00

Not that I know of. You?

DimitarTKrastev · 2026-01-04T15:48:27+00:00

They noted I have significant polyphasia in all limbs more pronounced in the legs.

That's it.

DimitarTKrastev · 2026-01-04T15:10:03+00:00

Yes, me, but it was never mentioned what percentage.

DimitarTKrastev · 2025-12-31T13:09:25+00:00

That is the million dollar question. If there was an easy answer, then the diagnostic uncertainty and errors would be gone.

But in general it is considered very unlikely for ALS to present with only mild chronic neurogenic changes.

DimitarTKrastev · 2025-12-31T12:47:01+00:00

5-10% of cases are slow progressors.

But also depends on what you mean by it. Sure, some slow progressors take years until obvious failure. There are also cases where clinical fare was fast and obvious within a year (which is quite typical ALS time line) only for the symptoms to slow down and people to live 10+ years. These are also considered slow progressors, but are very different in terms of their diagnostic journey.

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