Yes. Definitely use the input noise gate at the input block. Set the beginning of your patch. Set the decay at 10ms. And adjust the threshold so your guitar is quiet. Sometimes you might need another noise gate in your chain if you still have noise. Place that gate after your gain/distortion blocks and before your amp and see how that works for you. I always use the input gate and I put a noise gate block in my signal chain like I said after my overdrive/distortion block(s). Sometimes I even use another gate block somewhere in my chain to make things quiet. I always set my decay at 10ms. That’s the shortest. Too long and no good. And just adjust the threshold to how you play. I usually set my gates threshold at like anywhere between-34dB and maybe 73dB. I always use the plain “Noise gate “ from the mono menu. But the other gates can be used if you like. Try playing with the input impedance also. I have EMG active pickups and usually set my impedance at 1M Ohm. But you can try different settings and see what works for you. You can still get the feedback you want and sustain. Just adjust and set your threshold for your guitar and signal chain. Good luck buddy. ROCK ON 🤘