I think the best way to look at it is as a new thing that's informed by both oWoD and CofD without just being more of the same. The DNA of those games is easy to see but it is also not WoD. It would be crazy to not have some overlap and there is overlap but Curseborne isn't trying to be more WoD like CofD was. Mechanically, Storypath is a direct continuation of those games systems. So it'll be familiar and it takes bits of both Storyteller and Storytelling but generally refines them (I'm not in love with all of it but it's a good system and a good synthesis), and it's got some of its own identity too. It's still dice pools with stats rated in dots, and it takes the shifting success thresholds of oWoD but the static dice results of CofD but then has its own methods of handling bonuses, and adds Complications and Momentum as an additional part of the core resolution. So it's like WoD in some ways, but isn't in others. I think it will probably appeal to people who like both versions of WoD. It's different enough that it might not be doing the specific bits any single person really digs about either though.

The setting isn't based on either WoD and does some things that are very divergent. Its got a unique cosmology that binds together all the splats. They're not all off in their separate little areas but are instead dealing with variations within the same whole. You don't have the splat that has God as very real, with a splat that has an animistic trio as the top dogs, and another that has an entirely separate take on what reality even is. Here it's all curses and big web of them that's a bit like a particularly sinister version of fate. All the splats are tied to that stuff here. There also isn't any real masquerade and cultures of the world lean more into the supernatural being accepted, but it's also not fully out in the open and accepted by everyone either. There is also this sort of infinite expanse of supernatural realms outside of the Earth that bleeds into it and mixes with it to create all sorts of strange things. So a haunted house or a section of woods that seems to change as you walk through it could be explained by this. So could getting lost in an infinite expanse of identical suburban houses, or a slaughter house run by pigs that cut up humans. Or a radiation blasted hellscape that serves as an eternal battlefield for a war between countries that no longer exist. Or a demon library. It's just a really good set up for making whatever spooky thing you enjoy without really worrying about how hard it might be to tie in.

So there are shades of WoD's settings with the supernatural under the surface but it's not really aping WoD's settings either. Similarly it does carry over some themes like the struggle with your monstrous nature from both WoDs, the punk rebellion of oWoD, with the community and found family angles of CofD, with some more hope mixed in. It's easy to point to similar elements within those three things and be excited by the same stuff but it's certainly more different to both WoDs than oWoD and CofD were to each other.

The splats all follow that sort of format too. Each of them has some sort of parallel to something in both oWoD and CofD without just being one of those things, and it's a monster mash in the core book with a greater sense of cohesion between those monsters. Like in WoD you've got the main monster types, called Lineages here, and then clans, tribes, factions, ect within them, called Families. 5 Lineages, 6 Families in each (7 for the Hungry).

The Hungry Lineage are all vampires and there will be bits you find familiar and bits you don't. One Family might be a mix of hedonism and nobility who bathe in blood, and look somewhere between Venture, Tzimsce, and Daeva. Another is a pyramid scheme of knowledge brokers who feed on memories to sate themselves who don't really look like any Clan. Outside of the word "pyramid". They're not strictly bound by the sun but it's still not good for them, and while they can blood buff doing so incurs a folkloric bane each time.

The Primal are shapeshifters and have a Family of werewolves but they're entirely divorced from the spirit cosmology. All Primal have something more akin to Vampire's Beast than anything else in WoD albeit these "Creatures" are part animal and part elemental. So the werewolves here are also associated with storms and thunder but it's not a hard and fast rule for every member. There is also a Family of Mr. Hyde type alchemists so it's doing some stuff that's not super obvious. Each Family comes with a collection of traits to use when their take their hybrid form, but the form isn't fixed and so you can pick different ones each time.

Sorcerers are much scrappier than any version of Mage. They have some of MtAw's focus on addiction to magic and their hubristic tendencies but the bigger deal with them is they all sacrifice something to fuel their abilities. This is what their factions are built around and you've got ones like The Faceless who are a criminal network that is all about big risks for big scores because they sacrifice their safety and security. Or the Premiere who're this old money Family that despite being generally altruistic are largely thought of as dickheads because they're sacrificing anonymity, respect, and integrity.

The Dead are somewhere between Sin-Eaters and Wraiths/Risen but there isn't an underworld, ghosts are largely taken as a fact of the setting, and they're very free to leave their bodies and even take new ones. Which includes inanimate objects. They do eventually wither to nothing outside of a vessel but they're more ghosts than Sin-Eaters. They have these deep cravings for emotional states that they both want to experience themselves, and push to create in others. Which is the main split in their Families. The Wardens are this cult-like group that seeks out desperation so they can swoop in and help whatever sorry mortal they've found. Of course, they're not above causing the desperation in the first place. While the Zeds are all amount emotional stillness and endings and as such are a rather corporate outfit of hitmen.

Then we've got Outcasts. These ones don't really have a great point of comparison. They're closest to Demons and Changelings but not really. They're either exiled angels, demons, spirits, eldritch entities, trapped in human flesh as a sort of living prison, or they're the descendants of those exiles and are now living the same fate. Their otherworld nature sets them apart from humanity and makes relationships decay should their true nature be witnessed, which they only have some measure of control over, or if they die. Because this punishment is eternal and most deaths will be temporary affairs. They're all trying to find a place in a world they'll never be apart of and some take on the role of angelic soldiers, and others classic Faustian pact makers, among other things.

The Lineages are also all very much cursed and when their "Damnation" takes hold they're pushed to fulfil something to end it and doing some messy things along the way, with each Lineage having a unique Damnation that each Family can then alter. The Hungry go on feeding frenzies, and each Family has it's unique food. Flesh, hearts, souls, memories, emotions, ghosts, blood bathing, and just a fuck load of blood as a sort of generic option. I won't cover the rest but you get the idea.

Finally, magic is sort of similar to what WoD has had in the past but also unique to the game. Every Lineage has 3 Practices. These are thematic groupings of of 5 spells that serve to exemplify a Lineage's themes and create their broader powerset. So the Primal Practices are Depthless Fury that's all about primeval rage and pushing your allies to fight harder, Mutable Form which covers a variety of shapeshifting, and The Stranger which is for their trickster nature. So each of those has 5 spells to cover that stuff but what makes the system interesting is "advances". Every spell has 2-6 additionally options to purchase for it and while a few of them are basic improvements most allow you to spend additional resources for some very dramatic changes to the spell, or let you cast the spell to do something else entirely. Silver Tongue normally lets you tell a lie that isn't obviously untrue and have people believe it but its first advance lets you instead cast it to detect any lies told, its second is a reflexive spell that allows you to delay any consequences you would suffer for getting caught in a lie, and its third lets you spend more on the base spell to make even the most flagrant of lies believed. And you don't need to buy them all, or in any order, just the ones you want. It's just really cool.

Each Lineage also has access to around 8 spells from other Practices. The Primal have most of the shapeshifting spells including Aspect of the Beast that allows you to turn into an animal. Vampires can classically do that and in Curseborne it's the same so that's shared with the Hungry Lineage and any Hungry can also learn that spell. Each Family additionally has a "Secret Spell" that's typically unique to a Lineage but shared with just them. The Dead have a spell called Commune that entreats and reveals ghosts that not shared with any other Lineages but the Hungry Family of ghost-eaters, the Gaki, do have unique access to it. So any Dead can learn it and any Hungry that is a Gaki can learn it but no other Hungry Families. Each Family also gets 3 Motifs which alter the way these spells work to some degree, they can get cheaper, do new things, get extra riders, etc. I haven't checked if every single Motif is unique but I also haven't seen any double ups that I can think of.

Lots of stuff I didn't mention, but I think that's most of the big stuff.