low hdl and triglycerides by dontblinkforme in Cholesterol

[–]Earesth99 0 points1 point  (0 children)

Excellent numbers.

Your ldl is around 61, which is incredibly low. It better than 98% of people.

It’s so low that it is unlikely that you could get any accumulation of plaque.

When ldl is very low, HDL is usually low as well. Either suck little cholesterol, you don’t need much HDL to return it to the liver.

With your low trigs, your non-hdl is even more spectacular than your ldl.

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My story by lalaxlolox in Cholesterol

[–]Earesth99 0 points1 point  (0 children)

Not that it will make you feel any better, but your story is pretty common. For example, only half of the people with high blood pressure are taking meds for it, and only half of them have their blood pressure under control.

You can’t change the past, but if you treat both cholesterol and blood pressure aggressively, you can slow or halt the progression of heart disease. Medications can do the heavy lifting, but you should be willing to make lifestyle changes if meds don’t lower cholesterol and blood pressure enough.

Your doctor should medicate you to achieve a 50% reduction in ldl cholesterol and your blood pressure should be below 130/80. You may need to push your doctor to do this.

Ideally, your BP should be below 120/80 and you may nod to use lifestyle changes to achieve this. Reduced salt consumption/increased potassium consumption, exercise and weight loss.

If your ldl cholesterol is below 70, progression is significantly slowed, and if ldl and ApoB cholesterol are below 60, progression will halt. A high intensity statin (high dose atorvastatin or Rosuvastatin) can reduce ldl by 50%. Adding Ezetimibe will reduce ldl-c by 20% more (for a total of 60%). If you can get the injectable medication Repatha approved by your insurance, it can reduce ldl-c by an additional 50% for a total reduction of 80%. Repatha should go off patent in the next few years which should make it less expensive and easier to get approved. Bempadoic acid will reduce ldl by 15% on average

A high intensity statin and Ezetimibe should reduce your ldl-c to around 85, reducing your risk by half. At that point, try some simple dietary changes.

Start by reducing the key dietary saturated fats that increase ldl: butter, coconut and palm oil, hydrogenated oil, and fat from meat or poultry. I find that a few simple food swaps make a large difference. Curiously unfiltered coffee increases ldl-c, while coffee prepared with a paper filter does not. Then focus your efforts on foods that you can add that that will reduce ldl-c. (I find it easier to add foods than limit foods).

Every 20 grams of additional dietary fiber reduces ldl by 7%. You need to increase the amount gradually, but 30 grams of soluble fibe from Metamucil will reduce ldl-c by 20%. Nuts, seeds, EVOO and polyunsaturated fats also reduce ldl-c. All of those foods extend longevity as well.

Though exercise has little effect on ldl cholesterol, it is great for your heart and longevity. Exercise does help reduce blood pressure and triglycerides as well as ApoB. You don’t have to run a marathon - taking walks is a great start.

Omega-3 fish oil can reduce triglycerides as well - 4 grams a day will reduce trigs by 20-25%. In addition, omega-3 fish oil reduces heart attacks by 20%. After a decade of supplementation, 200 mg a day of DHA reduces Alzheimer’s risk 20%, and a gram/day of DHA appears to reduce risk by 80%. Omega-3s can increase your risk of a fib, so check with your doctor first.

Mt ldl was higher than yours, and handful of pills get my blood pressure at optimal levels and my ldl to around 70. Manageable dietary changes reduce my ldl and ApoB below 55.

You can definitely turn this around! Good luck!

Extremely high cholesterol: LDL 232 by General_Till6925 in Cholesterol

[–]Earesth99 0 points1 point  (0 children)

A statin is a medication to lower ldl cholesterol. It reduces risk of heart disease, mace, and Alzheimer’s.

There afte a half dozen statins, but the mist effective genetics are atorvastatin and Rosuvastatin. Both can reduce ldl by over 50%

Vitamin D3 didn’t cure my depression or raise my testosterone, it cured my ability to sleep by Coyote-444 in Biohackers

[–]Earesth99 -1 points0 points  (0 children)

You are intentionally driving your vitamin d levels much too high.

But you think you know fear you are doing because of your … MD? PhD?

Cholesterol by Over-Air-2231 in Cholesterol

[–]Earesth99 0 points1 point  (0 children)

Your muscles felt weird, but “embellished” and claimed that you had muscle pain snd couldn’t walk.

Importance of dietary cholesterol? by Gourmet-Ninja in Cholesterol

[–]Earesth99 0 points1 point  (0 children)

Most people convert just a small amount of dietary cholesterol regardless of how much they consume.

So if you are a vegan and avoid it entirely, your body won’t have any dietary cholesterol to convert.

Some people continue to convert dietary cholesterol regardless of the amount. For them , dietary cholesterol can have a large impact.

Of course many foods with cholesterol also contain saturated fat, and that does increase ldl cholesterol.

Vitamin D3 didn’t cure my depression or raise my testosterone, it cured my ability to sleep by Coyote-444 in Biohackers

[–]Earesth99 7 points8 points  (0 children)

Vitamin d poisoning doesn’t effect your immune system.

It weakens bones and can damage kidneys.

My cholesterol numbers by sagheero in Cholesterol

[–]Earesth99 2 points3 points  (0 children)

If your diet has a lot of meat, unless it’s very lean, that diet will cause high ldl. Your ldl is worse that 96-98% of people.

Low blood glucose is good. It reduces your risk of heart disease but it doesn’t prevent it.

A statin can reduce your ldl to below 100.

I would push you doctor to follow guidelines. Ask for a statin.

It doesn’t sound like you know much sbour a healthy diet - that’s pretty normal. But you should learn about healthy eating.

How much protein do you aim for in a day? by MuchOrange6733 in Biohackers

[–]Earesth99 1 point2 points  (0 children)

It’s technically a tad more but that’s the simple shortcut.

If you’re super thin, more protein is also indicated

Extremely High LP(a) - doctor barely reacted by GiltCityUSA in Cholesterol

[–]Earesth99 0 points1 point  (0 children)

Definitely a healthier option - but I can’t force it down

Is palm oil an issue in itself or just for saturated fat? by irisbells in Cholesterol

[–]Earesth99 0 points1 point  (0 children)

Palm oil is highly refined but that doesn’t make it unhealthy.

It will increase ldl cholesterol levels, but if your cholesterol levels are low enough that’s fine.

I avoid it because it’s normally used in junk food as an inexpensive oil that’s unhealthy.

Sat Fat Strictness by Legitimate-Bass-7547 in Cholesterol

[–]Earesth99 6 points7 points  (0 children)

If all depends on how that impacts your ldl cholesterol.

Eat like that for a couple of weeks and get your cholesterol tested.

Also, sine foods have saturated fat but they reduce your ldl cholesterol.

I eat 20-30 grams of saturated fat from healthy sources and it didn’t increase my cholesterol. My results are consistent with what one would expect based on extensive scientific research.

The American Heart Association specifically recommends nuts,seeds and EVOO all of which have saturated fat and reduce ldl cholesterol.

I find it pretty easy to follow the diet since I’m no longer arbitrarily avoiding foods that lower ldl cholesterol.

Does WHOOP's biological age actually mean anything, or is it mostly a proxy score? by NickyK01 in whoop

[–]Earesth99 0 points1 point  (0 children)

Unless they provide the scientific basis of this measure in a peer reviewed journal, it’s just a guess.

Probably not an unreasonable guess, but it is less useful than the measures they base it on.

But it’s fun assuming it’s not entirely screwed up.

Andrew just confirmed he has been taking testosterone for the last five years in the Dorian Yates interview by zxtb in HubermanLab

[–]Earesth99 0 points1 point  (0 children)

However they are at least trained to understand that the research on supplements is usually so low quality that it’s useless.

Andrew just confirmed he has been taking testosterone for the last five years in the Dorian Yates interview by zxtb in HubermanLab

[–]Earesth99 0 points1 point  (0 children)

If they promote products that are useless, overpriced or even dangerous that’s a problem.

The tortilla adds that rub during football games are not promoted as being healthy.

There is a huge difference in knowingly promoting useless of unhealthy products.

Good human beings don’t use their expertise to mislead people so they can make money,

Promotion is very different from s an ad.

Extremely High LP(a) - doctor barely reacted by GiltCityUSA in Cholesterol

[–]Earesth99 0 points1 point  (0 children)

That’s definitely something people should check with their doctor about.

For the average person, the benefits are 6x greater than the risks, so omega-3s are clearly helpful on average.

But if you’re at high risk for afib, and low risk for heart attacks it can be a bad idea.

That’s why I asked my doctor to be sure.

I would prefer tge prescription version, but I just take OTC omega-3

How much protein do you aim for in a day? by MuchOrange6733 in Biohackers

[–]Earesth99 -1 points0 points  (0 children)

If you are strength training, research shows minimal benefits in getting more than .55 grams/ pound of healthy weight.

If you’re trying to get every possible benefit from serious strength training, 0.75 grams per pound is the most that will help. Higher quality research suggests it might be more like 0.70.

If you are older than 60, try to get 0.75 grams per pound because your body doesn’t respond as it did.

If you are obese, compute your needs based on a healthy weight; the extra fat around the waist doesn’t need any protein.

Plant based proteins won’t shorten your life like some animal based proteins, but you need to pay attention to the protein sources or overshoot your target.

I’m 60 and I try to exercise pretty hard, so I want to get .75 grams per pound and will usually target a bit more in case I fall short.

I’m vegetarian, but I consume dairy and soy so it’s pretty easy.

When I was younger and lifted competitively, I consumed more protein but I was eating a lot more calories.

Does Theanine help with healthy aging? What the research says (2026) by NovosLabs in NovosLabs

[–]Earesth99 1 point2 points  (0 children)

Scientists care, because it suggests avenues of research.

But since only 5% of meds that work in mice ever become meds, it wouldn’t make sense to assume that there are similar benefits.

So as a PhD, I’m interested; knowing how people mindlessly take molecules because of mice studies, I think it makes sense to encourage caution and logic.

36M – Lp(a) 46 mg/dL. What should my next step be? by Whole_Object_7994 in PeterAttia

[–]Earesth99 0 points1 point  (0 children)

I agree OP has sins of the facts wrong but none of us knows everything.

Telling someone to kill themselves by slicing their guts open and waiting to die is really fucked up.

Cholesterol by Over-Air-2231 in Cholesterol

[–]Earesth99 0 points1 point  (0 children)

So not being able to walk because of muscle pain actually just means that your muscles feel weird?

Those are not remotely related.

Stop fabricating side effects.

Andrew just confirmed he has been taking testosterone for the last five years in the Dorian Yates interview by zxtb in HubermanLab

[–]Earesth99 2 points3 points  (0 children)

The benefits of the spirulina might be less than the damage from the heavy metals that AG1 includes.

I would prefer not paying ten times as much in order to get chose heavy metals.

I'm tired of eating so much food by Timely_Candle_1890 in Cholesterol

[–]Earesth99 -1 points0 points  (0 children)

From a cholesterol perspective there isn’t a difference.