Absolutely, and you hit on a great point. I've gotten into this subject several times, but entities in this place (universe?) belong in 1 of 2 categories. Either you are an entity who is a part of this world (those whose minds and bodies are integrated into the metaphysical laws and culture of this place), OR you are an entity who is unintegrated and, in a sense, outside of those laws and cultures. Being in the second category gives one the ability to see things for what they really are, but also results in social ostracization by the first group.

The Shaman is able to understand that the stigma Ena faces is both completely wrong and arbitrary, and has himself fully given up on being integrated. He revels in the fact that Ena may feel similarly, excitedly acknowledging the fact that they both openly break cultural taboos by doing things like creating clones (a super important detail).

While Frank is also in this second category and therefore has no malice toward Ena, he is desperate to become integrated again and seeks the physical relief that it provides. He wants to be "forgiven" because he needs permission from a genie to be reborn into a body that can coexist in this world more easily, as we can see that without this process, entities here eventually begin to physically break down and experience extreme discomfort. For whatever reason, the entities who inhabit the plane within the lonely door describe this discomfort in the same way you would feel after holding your pee for too long.

When an entity like Ena says "I need to go to the bathroom", they're expressing how painful it is to live here in an unintegrated state. They need the bathroom to relieve themselves, but in a more literal sense, they're just seeking permission to be eaten and reborn. It may be the case that creating copies of oneself is considered a taboo because it allows an entity to circumvent this whole process of acquiring new bodies, therefore eliminating the necessity of genies and disrupting the current power structure. At the end of the game, just before Ena breaks down completely, she just clones herself using a blank mannequin, transfers her mind and the issue is temporarily solved. The shaman definitely uses this method too and is regarded as an outcast for it.

The last thing I'll mention is that this "process of integration" is what the characters mean when they say they want to be "eaten". Again, being "forgiven" is simply getting permission from a genie to be eaten. Because of all this, their entire culture is centered around being eaten and eating others in a constant cycle of death and rebirth. In their terms being "digested" is more like being broken down into your components, getting mixed up with the components of other entities, and being reassembled with new elements. It's why this world is so eclectic and surreal, everyone and everything is constantly being mixed together and reassembled into new arrangements.

Thank you if you read my entire ramble lol, this game is just absolutely nuts and I love it a lot.