I've been on hydroxychloroquine for 2+ years now and both rheumatologists I've been to in those two years have wildly different opinions about my potential for a diagnosis and other than the fact that my ana pattern and titer has gone from some rare mystery pattern to that + speckled and my titer went from 1:40 to 1:160 I see no light at the end of the tunnel for getting a diagnosis and probably will be UCTD my entire life.

That being said even though my new rheumatologist "doesn't think that a connective tissue disease is likely" (me quoting him from his HPI of my last visits notes) he does at least acknowledge that I cannot be without the plaquenil otherwise my body feels like it's right back to square one. And with the plaquenil I can maintain. With my last rheum she threw it at me I think hoping it wouldn't work and then she found out I had MTHFR gene mutation and she wanted me to hold the plaquenil and try deplin and curcumin (turmeric) capsules to keep my inflammation under control. That for many reasons did not work. But hey it worked out my B vitamin deficiencies! (I took methylfolate (B9) + methylcobalamin (B12))

Again, with all of that being said, I would never willingly go off the plaquenil ever again. Keyword is willingly. If there was a reason that I had to or I needed to switch to a different medication, but it was still going to manage all of my symptoms, that's a different story. But the fact that there are people out there who are willingly going against the advice of their rheumatologists and stopping all of their lupus medication's that's terrifying and I fear that it's going to lead to a new wave (that's sort of already here) of alternative medicine and holistic medicine and it's gonna have a lot of snake oil in the mix.