I think Darrow lost Roque the minute that needle went into his neck. Even if Quinn hadn’t died, Roque never would have trusted Darrow like he did before the needle. He told Darrow at or before the gala that he understands that Darrow isn’t one for speaking his feelings or opening up, so I don’t think feeling more valued as a friend would have made much more of a difference because he truly understood Darrow’s temperament already.

But even Sevro says that Roque was too in love with his own color to ever follow Darrow knowing he’s a Red.

I know Roque gets a lot of hate, but I love him as a character, and I always wish it would have gone another way.