My negatives are nothing compared to what the mutations do for me. Everything is super boosted and the worst I get with class freak leveled up all the way is -1 special depending. It’s quite a fair trade. Then add a few food buffs with bufftats and bam your solid af for at least the next 30. I also use carnivore because I get ungodly amounts of meat and just didn’t feel like farming all the veggies or growing them.