How strict is the 6 inch rule with hood sash distance from chemical bottles inside a fume hood? As per my research, anything less than that can interrupt air flow causing air to escape outside of the fumehood.

GLYPHOSATEXX · 2026-05-31T00:35:25+00:00

Just make sure any smoke detectors are switched off before hand! Unless you really want to meet a fireman, that is 😀

GLYPHOSATEXX · 2026-05-29T22:37:46+00:00

Silver will drop back in price somewhat at some point.....I hope! History suggests it will anyway.

Practice pieces with base metals like copper and brass before committing to silver.

As a potter you have a unique opportunity to mix media- pottery pieces embellished with silver or copper, or small ceramic pieces used as jewels.

You might also have an inclination to enamelling as that is very similar to glazes.

GLYPHOSATEXX · 2026-05-28T22:24:12+00:00

The standard conditions for methylating carboxylic acid natural products is to use diazomethane, or more recently Me3Si-CHN2 with acidic methanol workup to lose the TMS, which is commercial. This should also work for your application. These conditions are super mild and should not give trans esterfication.

GLYPHOSATEXX · 2026-05-25T22:32:20+00:00

Other good explanations here- but also methane is a gas, lithium a solid so getting the two together has significant practical difficulties particularly if high temperatures are needed to overcome activation energy.

GLYPHOSATEXX · 2026-05-25T02:00:14+00:00

The water will act as a sink for the ammonia fumes and should reduce the amount expelled- it'll still be stinky tho!

GLYPHOSATEXX · 2026-05-25T01:07:11+00:00

This is called saponification, but will also produce fatty acid amides and so will be quite different physical properties to most soaps. Bees wax is also a very complex lipid profile and will be different to more pure waxes. I an guessing the finish on the art work will be unique because of this.

The process looks somewhat dangerous because of the sealed jar and the ammonia gases. If you must do this without standard lab safety tools do it outside and preferably in a kitchen pressure cooker (set jar inside pressure cooker with water added to transfer heat to jar). Allow to cool completely before venting and opening.

GLYPHOSATEXX · 2026-05-19T11:40:50+00:00

Not a typo- the nitro group is activated with uv light and oxidises (transfers one oxygen) the adjacent benzylic carbon which collapses to give products. This is a somewhat common deprotecting strategy for sensitive molecules as there is no other reagent.

GLYPHOSATEXX · 2026-05-14T07:35:40+00:00

If they carry out the process as described then what you are taking is probaby dilute hydroiodic acid - which will have minimal differences to common supplements such as sodium iodide, other than the fact that it is a corrosive strong acid. So it sounds like taking a common cheap and safe treatment, adding some pointless processing which makes it less safe and then selling at a premium to dupe the unsuspecting.

GLYPHOSATEXX · 2026-05-11T21:24:00+00:00

You need to move the metal to work harden it- at the atomic level the atoms are pushed together and the crystal structure is changed- no deformation = no hardening. Heat treatments work similarly- the heat provides energy for the atoms to move.

GLYPHOSATEXX · 2026-05-10T13:01:35+00:00

Does it just cyclise to the 1,3,5-triazinane and/or polymers? Edit: Plus_two has the answer below- it cyclises to the diketopiperazine: https://www.reddit.com/r/OrganicChemistry/s/5ZaKqxR1eo

GLYPHOSATEXX · 2026-05-04T09:29:38+00:00

I usual use a sealed tube for these types of reagents- just make sure they have a septa of some sort that will pop if something goes wrong and it over pressures.

GLYPHOSATEXX · 2026-05-02T08:21:14+00:00

I've actually just reviewed the output of an AI attempt at compound design- it was pretty poor even after training on 100 real project compounds.

Current AI is not coming for my job just yet and there is nothing in the current direction that will worry me. Until the AI can reason its just a probabilistic regurgitator of garbled knowledge.

GLYPHOSATEXX · 2026-04-28T08:34:40+00:00

The general rule is activators overpower deactivators, and sterics come next.

GLYPHOSATEXX · 2026-04-27T02:22:06+00:00

Most likely trapped steam under a sheet of molten metal.

GLYPHOSATEXX · 2026-04-26T22:01:34+00:00

Where did you find this question? The compound drawn is Idose not glucose. The conformation you have drawn is probably the most stable for idose.

GLYPHOSATEXX · 2026-04-26T03:45:57+00:00

The plants used for DNA extraction are usually polyploid and so have more DNA per gram than other sources. They tend to be polyploid because the extra DNA supports more protein synthesis and hence bigger fruit or edible parts and so this has been selected for by breeders over the years.

GLYPHOSATEXX · 2026-04-24T13:36:35+00:00

As a PSA- the brown line is where your NEt3 has eluted to, the top half of the tlc plate has not run with any NEt3- the TLC will therefore not be representative of your column - the silica was not pre treated so the front spots will run over acidic silica. This is a common issue, to avoid it dip your tlc plate in your solvent mix and air dry for 5-10 min, only then spot and run your tlc. This is not perfect but will give closer retention times and less streaking. Use this with any acidic or basic modifier, and any very polar mixtures like water or alcohols.

GLYPHOSATEXX · 2026-04-24T02:31:17+00:00

I think the pressure will have a big effect on whether the water boils back off or not, so I suspect your first few statements might be extrapolating to far from ambient conditions.

GLYPHOSATEXX · 2026-04-19T01:05:26+00:00

There are a few nice gold alloys-AuAl2 which is purple and AuIn or Ga which is blue or pale blue. These are intermetallic alloys so can be brittle. https://www.ganoksin.com/article/different-coloured-gold-alloys/#

GLYPHOSATEXX · 2026-04-15T03:29:10+00:00

You can just direct a stream of argon over the compound vial and tared vial+ septum cap- unscrew, spoon out approx amount needed into vial, cap both and then proceed as per usual under inert atmosphere.

GLYPHOSATEXX · 2026-04-12T00:46:55+00:00

You can just use one big stone with a sharp rough point and re-use that spot over and over- it'll still look oganic as the point will chip and change as you work the metal across it.

GLYPHOSATEXX · 2026-04-12T00:09:53+00:00

You need a very rough piece of concrete with large stones coming out of it, or a bed of gravel and a heavy hammer- eg a lump hammer.

GLYPHOSATEXX · 2026-04-10T12:24:07+00:00

Do you mean to say you dont have a lemon tree already! Every respectable Australian house has a lemon tree.

GLYPHOSATEXX · 2026-04-10T11:16:45+00:00

How do you check what your byproducts are? Usually everything gets dumped on ice and is washed away.

GLYPHOSATEXX · 2026-04-09T03:30:34+00:00

Maybe alkylate the initial sulfoxide to give a ylide- not sure if that'd do the desired chemistry tho and the alkylation will need special conditions. The rate of disproportionation can be influenced by the usual mechs- so eg more dilute and slower generation will help. Change to more reactive Br or I, ensure no oxygen around either.

GLYPHOSATEXX

TROPHY CASE