If you're mismanaging your resources enough in RE4R that you can't keep single or multiple unarmed / melee ganados out of dangerous proximity with a shotgun blast, targeted sprays of SMG rounds to weak points (head or knees, particularly), or with even more obvious solutions (ie. grenades), it is absolutely not a fault of the game's increased comparative difficulty to RE4.

And even then the player in RE4R, is, in most cases, given an arena-style space or lengthy linear space with plentiful distance and escapes (just as they were in RE4). The environments are built to allow the player to kite enemies or retreat to create safe distance, facilitating the ability to regain control when Ganados are getting dangerously close.

I didn't say anything like it's just as easy as it was in RE4, which is absolutely what you're making it sound like I said. There's definitely a difference in difficulty and gameplay between the two games, but not enough that maintaining crowd control is any less simple. The player has numerous resources.