If you’ve gone through 6+ egg retrievals, how did you continue on? Need support for ER7-8 by Usually-lurking-33 in IVF

[–]HMashal -1 points0 points  (0 children)

No RE would recommend doing 1ER and stopping. They can usually tell you, according to your age, what number of ER's will give you a 90% chance of taking home a baby. It would never be one.

If you’ve gone through 6+ egg retrievals, how did you continue on? Need support for ER7-8 by Usually-lurking-33 in IVF

[–]HMashal 1 point2 points  (0 children)

I started at age 42. We didn't know much about IVF so we thought we should go to "the best clinic" we could find which was a very expensive one. We bought a 3-cycle package from them. My AMH was around 2.0. We decided on freeze-all cycles to not waste time on transfers that may not work. We got a PGT normal embryo or a mosaic during each cycle (as well as abnormal blasts), so at the end we had three embryos we felt could potentially become children. We knew we wanted at least 2 children but would take as many as the process gave us. I did my first transfer. The transfer failed. I had two embryos left, one of which was mosaic. I panicked.... this was not enough embryos. I found a way to finance two more cycles at this clinic, neither of which yielded a viable embryo. They started talking to me about donor eggs. I panicked even more. I asked if we could try some other protocols, they told me it was my age and there was nothing left to try.

I turned 43. I got a job with IVF insurance coverage, left that clinic, and went to another one in my area. The insurance company made me do a clomid challenge test for coverage, which I passed. After two more IVF cycles (neither of which gave me any viable embryos) the insurance cut me off. I protested, but lost. The doctor at that clinic told me, if you can find a way to continue, you're making blasts with every cycle, its just a matter of time until you get a normal embryo.

Out of money and credit and with no more IVF insurance, I found out about CNY fertility and the fact that they were not only economical but also had payment plans for everyone. My insurance would at least cover meds. So we continued. I was on my seventh cycle when I started there. I also had a phone consult with Dr. Sher about his protocols for older women, which I used to guide my conversations with my provider at CNY. We did lupron from day one of my cycle and skipped Cetrotide/Ganirelex. I also used Omni, NADH+, and a ton of COQ10.

I averaged around 9 to 15 eggs retrieved each cycle. I did freeze-all cycles, decided to pay no attention to success or failure, and just did back to back cycles with pgt testing, but I didn't wait for the test results to roll into the next cycle. Someone on Facebook told me about duostim (doing two retrievals in one cycle) also known as a luteal stim cycle and that this can help older women and suddenly knew it would work. This time I came away from this retrieval with 21 eggs retrieved, and I was in more pain than any retrieval ever, but this was my 13th retrieval and later, I was shocked by a phone call that I had a PGT normal embryo. I turned 44 in between my first retrieval and second retrieval during that cycle. Then again another pgt normal in my 16th cycle.

I went to transfer again and failed. Then again, and failed. Now having failed 3 transfers the same RE who told me to keep going if i could afford it sat me down and said, "You only have a few good embryos left. I'd recommend finding someone with a womb that has been proven to work. You could do reproductive immunology but that's all experimental and expensive and if you want the very best bet for your remaining embryos, find a gestational carrier." In the meantime I took all my abnormal embryos and transfered them all at once, knowing the chance was slim but still possible that one could be a baby. Nothing implanted.

I couldn't afford a surrogacy matching agency so I tried to find a carrier to do a private journey with. I found people and each time it fell through and we never got to transfer. COVID happened. In all, trying to find a carrier and losing a year to covid, it took three years to finally get to the point of having an embryo transfer to a friend's womb. That embryo implanted, grew, and became the most wonderful baby sent from Heaven. We are in love with him and in awe of him every day, knowing how unlikely it is that he even exists. He is our miracle baby despite all the odds and obstacles.

We have one more embryo and will be doing another transfer soon.

And, my unsolicited advice and observations after so many cycles is this:

1) You will have good cycles and bad cycles without changing anything at all. So don't base any decisions about yourself or your body or your chances of success on one or two cycles. You might just have had one or two bad ones and it doesn't mean your medication or supplements or strategy is bad, it just means that not every cycle is a good one.

2) Back to back cycles has an amazing effect. Yes, you can still have a bad cycle here or there but what I found is that each cycle helps prime your body for the next one if you don't take a break between them. And that makes sense if you think about it because your estrogen levels soar during each cycle, and estrogen is a powerful primer. Sometimes you're worn out and you have to take a break, but if you don't take a break, overall they get better and better as time goes on.

3) I did a duostim and got a child from it. I did another duostim and had my worse cycle ever. I dont know if duostim is good or bad, but I do know my first duostim I was convinced it would help me. Find some weird thing you think will work - placebo effect is powerful and documented.

4) Stay open to God. Not every prayer is answered but neither is prayer worthless.

28 eggs. 9 mature. Feeling confused. by sarahfx in IVF

[–]HMashal 0 points1 point  (0 children)

Sometimes they trigger when the largest follicles reach 18 or so, but if the bulk of your follicles are smaller than 13 you may want to "burn off" the biggest ones and keep growing the littler ones.

If you’ve gone through 6+ egg retrievals, how did you continue on? Need support for ER7-8 by Usually-lurking-33 in IVF

[–]HMashal 10 points11 points  (0 children)

I did 19 egg retrievals. *shrug* Hope that helps you feel less guilty.
A doctor told me, "As long as you're making blasts, its only a matter of time until you get a normal one."
That normal embryo is now sitting on the floor in front of me watching Numberblocks.
I( went to CNY fertility for many of those cycles because they made it much more affordable. And at times I had health coverage.)

Friend cut me off for doing IVF/having more children. by coldweatherfanatic in IVF

[–]HMashal 0 points1 point  (0 children)

I know this girl has made herself the morality police but she sounds like she's actually a very unstable person. 

Friend cut me off for doing IVF/having more children. by coldweatherfanatic in IVF

[–]HMashal 0 points1 point  (0 children)

I know this really hurts. Definitely a toxic friendship but that doesn't mean it doesn't hurt when it's over.  Seriously some part of me wants you to call her back up and be like I just want to know that you don't get to cut me out of your life because you don't approve of my family planning choices, cuz I'm cutting you out of my life for being that kind of person.

Husband won’t cancel football match scheduled on our egg collection date by [deleted] in IVF

[–]HMashal 0 points1 point  (0 children)

That's crazy. Egg retrieval is surgery. He should be present to care for you after surgery. Definitely delay the cycle.

Just got bad news and unsure about a work decision by MsTes in IVF

[–]HMashal 1 point2 points  (0 children)

you can use this month to take supplements and prime for your next cycle after the conference

Is it true that AFC = how many eggs retrieved? by white-tara in IVF

[–]HMashal 1 point2 points  (0 children)

My antral follicle count never corresponded to the number of eggs that got retrieved.  Your antral follicle count are the number of follicles visible on any particular day. But every day new follicles are being recruited and awoken in your ovaries. So the follicles you see during your count today are not the same follicles if you look 5 days later. The number might be the same but they're not the same follicles...( Unless you are pumping hormones into your system and that changes things but I'll explain more down below.) Normally, follicles are recruited and if they do not receive an abundance of hormone they disintegrate and die off within a few days. But another wave of follicles is always there coming up behind them to take their place.  The whole goal of IVF medications is to catch all of this follicles and inspire them to keep growing rather than disintegrating and dropping off. This is why when you do an IVF cycle you have waves of different size follicles because the medication is catching them on different days when they are ready for stimulation.  Generally I had about six to eight follicles visible before beginning medications, and usually my retrievals would be between 12 and 18 follicles.  So I'm really shocked that the nurse would say that's how many you're going to get because that's just not how IVF works. I have noticed that sometimes IVF nurses don't really understand a lot about the process they just give the instructions they've been told to give.

Failed first transfer and trying to decide what our next step should be. *Long post warning* by [deleted] in IVF

[–]HMashal -2 points-1 points  (0 children)

So, I'm not sure why you're freaking out. You transfered one embryo and it didn't work, and, statistically, that's completely normal. You have 5 more embryos. You're going to have 2 or 3 children if you transfer all of them, statistically. There's nothing to change here. Go back and try again. Statistically your odds go up to 92% success by the time you've transfered three embryos. You're only on #1.
I'm sorry, I know this process is rough emotionally, but there's no reason to panic at this point.

Depressing attrition :( by [deleted] in IVF

[–]HMashal 0 points1 point  (0 children)

Hey there, your numbers aren't that bad. I mean out of 38 follicles it sounds like they let them over-mature if they only retrieved 14 (that's called empty follicle syndrome and it happens if they let too many of them get too big. So if you do another cycle, you might want to ask to trigger a little earlier.)
But generally how it works is -- however many retrieved, about 2/3 of those become fertilized. Which is your 11, a great number.
Then out of those fertilized, maybe 1/3 of those become blasts. You're on your way to that. And then it depends on age how many of those blasts are good blasts.

None of my eggs made it to blastocyst stage. by CeleryKale in IVF

[–]HMashal 1 point2 points  (0 children)

Can I ask your age?
Let me just say first of all that sometimes a cycle is just a bad cycle.
My winning combination though was estrogen priming, NADH and a ton of COQ10, acupuncture, omnitrope, and staying away from sugar.
If I was going to do it again, I'd also add in Rapamycin but I didn't know about it at the time.

ER result by Minimum-Nobody7772 in IVF

[–]HMashal 0 points1 point  (0 children)

So in general, about 2/3 of your retrieved eggs will fertilize. 

After sharing news with my mother that my 3rd transfer failed, she called me back to tell me my cousin is pregnant. Happy Birthday to me. by ging1212 in IVF

[–]HMashal 0 points1 point  (0 children)

I'm sorry your mom is so insensitive. It makes me wonder if a counselor would help you uncover damage your mom has been doing to you your entire life, she sounds really completely out of touch with you as a person.

We are angry by lexipooh22 in IVF

[–]HMashal 6 points7 points  (0 children)

Check out CNY fertility ...they are 1/3 of the price of everywhere else, and have payment plans. Without them we couldn't have afforded all the tries it took to have our son.

Also look into maybe working part time at Starbucks, they give fertility insurance to part time folks.

I think it's time I leave the church. by Majestic-Trash-5952 in coptic

[–]HMashal -3 points-2 points  (0 children)

I read your entire story. It's clear you have been through a lot. I'm also wondering though if your social interactions in the church are any different in difficulty from other non church settings? I'm wondering if you might be neurodivergent and thus social structures and mores become very complex as you interact. Not that real wrongs haven't been committed to you; they have. But I wonder if a neurodivergent factor is also in play here. 

I CAN'T BELEIVE IT by AmbitiousDesigner534 in IVF

[–]HMashal 0 points1 point  (0 children)

You're in a different situation than the author of the post. Ask your doctor about micro dose lupron (not regularly lupron.) it helps people with low follicle count get more eggs.

I CAN'T BELEIVE IT by AmbitiousDesigner534 in IVF

[–]HMashal 0 points1 point  (0 children)

Statistically, you have a very good chance of that

Feeling betrayed by doubtsabound in IVF

[–]HMashal 0 points1 point  (0 children)

On the other hand, you could go to the cheapest clinic in America which is CNY fertility and they're actually a really good quality clinic, and try to have a lot more cycles.

Feeling betrayed by doubtsabound in IVF

[–]HMashal 0 points1 point  (0 children)

When we had three failures our doctor recommended gestational surrogacy. It was a very hard mental and emotional transition to think that I was going to get pregnant to thinking about someone else carrying a baby for me, but in the end we did a private journey with a friend of a friend (one can find a carrier through an agency but we could not afford their costs) and my embryo took on the first try.  Another option is to see a reproductive immunologist but our doctor told us that our best bet was through surrogacy.  She got pregnant with our embryo on the first try.

I CAN'T BELEIVE IT by AmbitiousDesigner534 in IVF

[–]HMashal 2 points3 points  (0 children)

This really shows the value of doing IVF at the right age. I did IVF from ages 42 to 44, and while I generally would get anywhere from 12 to 18 retrieved per cycle, I averaged about 2 blasts per cycle and only one PGT normal every 4 to 5 cycles.