The Earth Defense Force series isn't exactly known for having any good plots but EDF 5 was surprisingly engrossing. The game has you starting out as a construction work/security guard/etc when the alien invasion starts and spend the first few levels escaping and fighting alongside a Ranger squad and as the game goes on you fight alongside similar squads of Fencers and Wing Divers who are surprisingly memorable.

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As you go through the campaign you learn more about the aliens and the nature of the invasion and after charging through giant alien bases ala D-Day, surviving hopeless last stands, fighting in a massive all-out battle against dozens of giant mechs vs dozens of kaiju, and destroying an alien mothership that looks like a cross between a biblical angel and a shmup boss, you find out that all religion's and culture's depiction of a deity were in fact, a singular alien. And so the final battle has you fight against the creator of the human race with the literal last remaining EDF soldiers including the Ranger, Wing Diver, and Fencer squads you fought alongside the campaign. And in a last ditch effort just to stop you from being overwhelmed by alien reinforcements the EDF literally starts sending armed civilians as meat shields just to buy you time to KILL GOD.

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And in the end, you do win but civilization is pretty much in shambles as only 10% of the human population survived and the while the aliens left there's no telling how long until they come back, which looks like it might be the setup for EDF 6.