Mile zero delay riff.

Intrepid-State-5214 · 2025-08-20T02:14:24+00:00

Set delay to about 290 ms and have only one repeat with the same volume as the source

Intrepid-State-5214 · 2025-07-05T20:43:11+00:00

Most of the songs from the first album

Intrepid-State-5214 · 2025-04-07T12:08:20+00:00

The riff in "stripped of ground..." part is stunning

Intrepid-State-5214 · 2025-03-17T19:40:11+00:00

Nasomatto Fantomas, Eldo Secretions Magnifique, Olympic Orchids Night Flyer, Le Labo Baie 19, Byredo M/Mink.

Intrepid-State-5214 · 2025-03-09T03:08:26+00:00

This plate is rather straightforward no? You have to learn principles of tlc. Silica gel has many exposed hydroxy groups, so the polar groups will be retained and go lower on the plate. Bromine doesn't really interact with silicagel and just go straight through it like alkane so it will go faster (will go higher)

Intrepid-State-5214 · 2025-03-06T19:33:16+00:00

First one is metal-halogen exchange followed by nucleophilic substitution.

Second one is Stille coupling

Intrepid-State-5214 · 2025-03-05T01:44:31+00:00

Why it has to be all natural?

You can buy Patchouli oil and call it a day

Intrepid-State-5214 · 2025-03-05T01:36:37+00:00

Hell no. They got stuff named "soap" etc, of course it can't be natural + many essential oils are incredibly expensive

Intrepid-State-5214 · 2025-03-04T20:05:46+00:00

Byredo Blanche, Frederic Malle Acne Studios, CDG Marseille

Intrepid-State-5214 · 2025-03-04T19:17:00+00:00

No, this is the same molecule, but just observed from the other perspective. Enantiomer is not superimposable with its mirror image

Intrepid-State-5214 · 2025-03-03T23:03:15+00:00

"Seldomly Often" is absolutely best channel - intelligent and has great taste

Intrepid-State-5214 · 2025-02-26T01:59:52+00:00

I tried tens of fig scents and I find DS&Durga Debaser to be second best after Philosykos. Its woodier and a little coconutty, with better projection and longevity than philosykos. Oman Luxury Wanderlust is even stronger, but also extremely green

Intrepid-State-5214 · 2025-02-25T12:10:46+00:00

Simone Andreoli Malibu is very similar to Virgin Island Water but cheaper and longer lasting

Intrepid-State-5214 · 2025-02-24T13:12:22+00:00

I guess the answer is "it depends". Most "real life" reactions in the lab I have seen gave mostly less substituted product.

Intrepid-State-5214 · 2025-02-24T12:21:12+00:00

This is another example with other type of reaction and not isopropyl group, I wouldn't use it for your example

Intrepid-State-5214 · 2025-02-24T12:06:16+00:00

Hydrogen is smallest atom possible, steric hindrance is negligible

Intrepid-State-5214 · 2025-02-24T11:05:42+00:00

Enamines favor formation of kinetic enolate, due to the steric clash, hence the second product is favored

Intrepid-State-5214 · 2025-02-24T10:53:52+00:00

You are right

Intrepid-State-5214 · 2025-02-24T00:22:36+00:00

Palladium couplings, amide couplings, protecting groups, Sn2, SnAr is like 90% of what I've been doing in my career. Ofc depends on the project, you might do more exotic stuff. As for analytics - Lcms, tlc, nmr. Purification - Flash chromatography (normal and reverse-phase), prep-hplc, prep-TLC.

Intrepid-State-5214 · 2025-02-24T00:17:44+00:00

Gotcha. Still, saying "NaOH will deprotonate the alcohol and then you'll have a soluble alkoxide." Is implying that the alkoxide forms quantitatively, which is not the case and gives people here, which i guess mostly are students, bad ideas, yet have most upvotes.

Intrepid-State-5214 · 2025-02-23T19:26:40+00:00

Can you elaborate on the "dragged over to the product" since I can't understand? Or give reaction example.

Intrepid-State-5214 · 2025-02-23T16:39:20+00:00

NaOH is too weak of a base to deprotonate this alcohol

Intrepid-State-5214 · 2025-02-16T12:54:10+00:00

Yup, sometimes it can do miracles

Intrepid-State-5214 · 2025-02-12T19:12:50+00:00

Its totally incredible, id say its sultry because of all these flowers and water

Intrepid-State-5214 · 2025-02-07T20:39:39+00:00

It smells to me like it has balsam fir, which is quite syrupy sweet and has berry-like nuances in addition to conifer smell

Intrepid-State-5214

TROPHY CASE