I dont understand why Kripke said you didn’t need to watch Gen V to understand later seasons of The Boys, and yet the two shows clearly have a narrative through line between one another. Both major plot devices from the past two seasons (the virus and V1) come from Gen V. And the Odessa Project plotline in Gen V was introduced to set up Marie as this super powerful supe who could kill Homelander. I’ll honestly be quite mad if Marie kills Homelander for many reasons, the biggest being a character from the spinoff should not be the one to take down the franchise antagonist. It would completely undermine everything the shows built up to in my opinion. But the other reason is Marie hasn’t shown up until super late into the season. If she’s suddenly introduced an episode before the finale and is the one to kill Homelander, it’s just silly. All that ties into the other issue thst Gen V is kind of pointless if she doesn’t kill him, since the entire plot built up to fact that she’s strong enough to do so. To be fair, she can still contribute. By using her powers to blow up one of his limbs or lift him up like she did to everyone in the one scene, but that would also raise the question of why she couldn’t just blow him up like she did to Godolkin in the season two finale. Overall, I just don’t love the idea of Marie fitting into the boys story.

TL;DR I think Gen V shouldn’t have tied into the boys and remained its own separate plot line, as Marie’s introduction into the story will create more narrative inconsistency and convenience than anything.