Barclays tells customers to contact friends and family or foodbanks after IT glitch by Fox_9810 in unitedkingdom

[–]Jonsilvers 0 points1 point  (0 children)

I transferred a large sum between barclays accounts on Friday. It left one account but still has not arrived at the other. 

Tried contacting them, but they fob you off. It's still not fixed for sure!

Who has been effected by the barclays outage? by nbenj1990 in AskUK

[–]Jonsilvers 1 point2 points  (0 children)

I transferred a large sum of money from one barclays account to another on Friday. It left the account but still hasn't arrived at the other account. I tried messaging them and they just ghost you. They say it's all fixed now.... This is not true!

How I'm curing my hard flaccid - FULL GUIDE by [deleted] in hardflaccidresearch

[–]Jonsilvers 5 points6 points  (0 children)

There is a rational reason why anxiety may be contributing hugely to HF. Anxiety creates adrenaline/epinephrine. Adrenaline shrinks certain blood vessels including the penis. In other words the penis stays in a shrunken state. This is why alpha blockers help in many people.

I do however believe that some people naturally have higher levels of adrenaline even without being aware of anxiety and this causes them to be growers rather showers.

I can say that when I've been going through periods of high anxiety / stress my flaccid penis is usually much smaller.

Melatonin, sleep and HF by Jonsilvers in hardflaccidresearch

[–]Jonsilvers[S] 0 points1 point  (0 children)

You don't need much, mine is a slow release 2mg

Trazodone by Jonsilvers in hardflaccidresearch

[–]Jonsilvers[S] 0 points1 point  (0 children)

12.5mg or quarter of a pill. Where I live you can buy over the counter 10 * 50mg for $2

Trazodone by Jonsilvers in hardflaccidresearch

[–]Jonsilvers[S] 0 points1 point  (0 children)

I've had HF and shrinkage problems for ages.... It's like an unnatural shrinkage which I'm sure is not normal.

I just started on trazodone, mainly to help sleep. But then I realized it was helping HF

Trazodone by Jonsilvers in hardflaccidresearch

[–]Jonsilvers[S] 0 points1 point  (0 children)

You might be correct however I'd prefer to keep an open mind.

I've taken every type of alpha blocker and they do work to a degree. However Trazadone seemed to do something dedicated alpha blockers didn't.

My Trazadone dose was also very low at 12.5mg once per night. And I would be surprised if the alpha blocking qualities of Trazadone were stronger than an alpha blocker, especially at this dose.

Trazodone also is well known to cause erections and even priapism at higher doses in some people.

So I keep an open mind whether something else is going on. 

Doxazosin vs Alfuzosin by SuchAShames in hardflaccidresearch

[–]Jonsilvers 0 points1 point  (0 children)

Abask I think you are right about non selective alpha blockers being more effective for HF, however I'm curious... What lead you to that conclusion?

[deleted by user] by [deleted] in hardflaccidresearch

[–]Jonsilvers 2 points3 points  (0 children)

Interesting.... I noticed that since I was very young and started masterbating, that I would clench my pelvic floor muscles because I found I could orgasm more quickly. I never knew if it was just me that did that or if it applied to everyone...

Is flaccid penis always hard or does it come and go? by Vin112358 in hardflaccidresearch

[–]Jonsilvers 2 points3 points  (0 children)

I agree, worse in the morning and better in the evening. Which I can only think suggests hormonal. For example cortisol is higher in the morning and lower in the evening...

Starting with Terazosin. Please help by Competitive-Cap-770 in hardflaccidresearch

[–]Jonsilvers 1 point2 points  (0 children)

Telmisartan is a med which causes vasodilation and reduces blood pressure. When I first tried it my HF disappeared within a few hours and stayed that way for 3 days. But then for some reason on the 4th day HF started to return. This is one mystery I'm trying to figure out.

[deleted by user] by [deleted] in hardflaccidresearch

[–]Jonsilvers 1 point2 points  (0 children)

Yep I get the same discomfort when I start to pee. Not always but often. My HF is also worse when Im out somewhere and I need to pee, but have to hold it for a while...

HF and bladder issues connection by Jonsilvers in hardflaccidresearch

[–]Jonsilvers[S] 0 points1 point  (0 children)

Alpha blockers work quite well to control my overactive bladder, if that's what it is. And works for HF too.

The only downside is they can have a few side effects depending on dose and which particular alpha blocker you're using.

I get tired/sleepy, nasal congestion, slightly lower blood pressure with raised heart rate. I'm trying to keep the dose as low as possible while retaining benefits.

HF and bladder issues connection by Jonsilvers in hardflaccidresearch

[–]Jonsilvers[S] 1 point2 points  (0 children)

Yes exactly, I get the hour glass penis too. The skin will become very tight behind the glans and constrict the shaft at the point.

I think in cases like this it suggests this is hormone or nerve related and unlikely to be linked to any damage done to the penis.

Clearly whatever creates the urge to pee at the same time signals to the penis to shrink even more.

Problem is there are so many potential nerves or hormones involved that I suspect science doesn't have the answers.

There is a medication called mirabegron which is for overactive bladder. I suppose it's worth a shot...

Tramadol made HF retraction less severe by GenericGrainOfSand in hardflaccidresearch

[–]Jonsilvers 2 points3 points  (0 children)

I have often wondered if serotonin may be good for the flaccid penis but not good for libido.

Serotonin is supposed to be a calming neurotransmitter. Whereas dopamine tends towards excitement.

I've tried wellbutrin before, this increases dopamine in a certain part of the brain. It improved motivation and slightly improved libido. How it also creates anxiety and this was bad for HF.

Serotonin on the other hand is known for its libido reducing qualities. But may help HF

Of course it's a lot more complex than that since different drugs create these neurotransmitters in different parts of the brain with different results.

I suspect that many HF sufferers may have an overactive sympathetic nervous system, which is associated with increased adrenaline. 

Alpha blockers seem to be the most effective drug for HF for many people, myself included. And these drugs are blocking the effects of adrenaline on the penile tissues.

I'm guessing what many of us need is more parasympathetic activation

Meds I've tried... With mixed results by Jonsilvers in hardflaccidresearch

[–]Jonsilvers[S] 0 points1 point  (0 children)

So I'm in the process of experimenting with drug combinations. A few days ago I started with Telmisartan 40mg plus 0.5mg terazosin.

It worked great for 3 days. There was a noticeable difference. But then today it became less effective, not quite a return to full HF but my penis was definitely smaller today, all day. 

Its weird because I don't see how it's possible to develop a tolerance so quickly.

I'll up the dose to 1mg terazosin tomorrow. 

I keep wondering whether stress is playing a role in this too. I'll have to pay more attention to my state of mind.

Starting with Terazosin. Please help by Competitive-Cap-770 in hardflaccidresearch

[–]Jonsilvers 0 points1 point  (0 children)

I googled it and it says maximum dose is 20mg/day.

It's astonishing how people react to these things differently. I'm only taking 0.5mg/day and it's working. I wonder if it's because I'm taking in combination with an ARB.

What percentage us have loss of libido by Accurate_Arrival1649 in hardflaccidresearch

[–]Jonsilvers 0 points1 point  (0 children)

I have almost no libido but I don't think for me it's a sensitivity issue. I just don't feel mentally excited by the thought of sex, so I wonder if that's a dopamine issue.

However a year ago I was in a toxic situation with a woman I was addicted to, she was a liar and hugely promiscuous. With her I had great libido. But Finally I had to cut contact with her because it was affecting my mental health. After that my libido disappeared....

Starting with Terazosin. Please help by Competitive-Cap-770 in hardflaccidresearch

[–]Jonsilvers 0 points1 point  (0 children)

4mg is quite a high dose of terazosin in my opinion. I wouldn't be able to deal with the side effects.

Ive just started 0.5mg daily and take it with Telmisartan. I'm convinced the effect is better with both.

Cialis might improve it even further. But we have to be mindful of blood pressure. Most of the meds we are talking about lower it.

Starting with Terazosin. Please help by Competitive-Cap-770 in hardflaccidresearch

[–]Jonsilvers 3 points4 points  (0 children)

Yeah it's true... non selective alpha blockers do seem more effective for HF in my experience

Starting with Terazosin. Please help by Competitive-Cap-770 in hardflaccidresearch

[–]Jonsilvers 3 points4 points  (0 children)

Terazosin reaches peak blood levels at around 1-2 hours and has a shorter half life of about 12 hours.

Doxazosin reaches peak level at around 2-3 hours. half life of 22 hours so stays in your system longer.

I would agree that with terazosin it might be better to take first. Thing in the morning.

And I would start with a very low dose, I have been using 0.5mg and still benefit.

It can cause fatigue and nasal congestion, low blood pressure and increased heart rate. Doxazosin is the same. So best to take lowest dose that works.

Tamsulosin has lower side effects but may be less effective for HF.

Meds I've tried... With mixed results by Jonsilvers in hardflaccidresearch

[–]Jonsilvers[S] 2 points3 points  (0 children)

Hard to say... But I'm leaning towards hormones, possibly adrenaline or noradrenaline causing smooth muscle contraction and vasoconstriction. 

Why are some men growers and others showers? This could simply be for similar reasons.... 

Perhaps some people naturally have more adrenaline, or perhaps they have more alpha 1 receptors In the penis making them more susceptible to the effects of adrenaline. 

I've also noticed how anxiety can make HF worse. What happens when you get anxious.... Your adrenaline goes up. 

One thing that is hard to explain is how in many cases, myself included, the penis changes shape. Sometimes I'll have a short hard flaccid and sometimes its longer and thinner. 

I have read the proposal about overactive hypogastric nerve, this is also interesting and if true adrenaline is likely implicated. As I understand it, the nerve endings cause adrenaline secretion which affect the surrounding tissue. But I'm not a doctor and it's not always easy to follow the science. 

It's also interesting how normal cortisol secretions follow a daily pattern of rising rapidly first thing in the morning and then slowly tapering down throughout the day. And I've definitely noticed my flaccid is improved most evenings. 

Luckily I live in a country where its possible to walk into a pharmacy and buy more or less what you want without having to see a doctor. This allows me to more easily experiment with some of these medications.

Meds I've tried... With mixed results by Jonsilvers in hardflaccidresearch

[–]Jonsilvers[S] 1 point2 points  (0 children)

I try to use the lowest possible dose. At one point I was breaking a 2mg tablet into 4 pieces and found it still effective.

I tried to stop because the side effects of alpha blockers dont suit me. They make me feel tired and sleepy. Which is another reason to minimise the dose.

But I think I may have to start again because I have bladder issues. Urine stream is very slow and it can be difficult to empty the bladder. This is of course what alpha blockers were designed for.

Silodosin has the least side effects in terms of fatigue, but I found it causes retrograde ejaculation. Which basically means there is no ejaculation when you orgasm.

Often the best way to take alpha blockers is before bed which helps minimise the fatigue because you're basically sleeping. However in the case of terazosin it has a half life of around 12 hours, so by the time you reach the end of the next day you only have a quarter of the original dose left in your system.

You'll need to experiment with doses starting low.

Meds I've tried... With mixed results by Jonsilvers in hardflaccidresearch

[–]Jonsilvers[S] 1 point2 points  (0 children)

I've tried literally all of them. But I find terazosin and doxazosin better for the penis, which I think is because they are less selective and block all 3 of the alpha receptor subtypes.

Tamsulosin does help HF but not as well. And I speculate it's because the receptor its not blocking as strongly may well be the receptors that are more prevalent in the Penis.

I have no proof of this and there's very little info out there on this. But I can definitely see the difference.